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  • Investigating the ageing-Parkinson’s disease nexus: standardisation of in vitro models and techniques by the PD-AGE network
    2025
    Summary Details
    OPEN
    Title: Investigating the ageing-Parkinson’s disease nexus: standardisation of in vitro models and techniques by the PD-AGE network
    Author(s): Alexander G. Bury, Alicja Olejnik, Chiara Tocco, Nathalie Saurat, Elezabeth Stephen, Dirk Hockemeyer, Jens C. Schwamborn, Lorenz Studer, Pier G. Mastroberardino, Silvia Bolognin, Tilo Kunath, Viktor I. Korolchuk, Janelle Drouin‐Ouellet, Heather Mortiboys
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-025-01137-2
    Best OA location URL: https://doi.org/10.1038/s41531-025-01137-2
    Citation Count: 0
  • Compensatory Mechanisms Nine Years Before Parkinson's Disease Conversion in a LRRK2 R1441H Family
    2021
    Summary Details
    RESTRICTED
    Title: Compensatory Mechanisms Nine Years Before Parkinson's Disease Conversion in a LRRK2 R1441H Family
    Author(s): Sara Sambin, Sonia Lavisse, Caroline Decaix, Nadya Pyatigorskaya, Graziella Mangone, Romain Valabrègue, Isabelle Arnulf, Florence Cormier, Suzanne Lesage, Stéphane Lehéricy, Philippe Rémy, Alexis Brice, Jean‐Christophe Corvol
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 37
    Issue #: 2
    Start Page: 428
    End Page: 430
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.28833
    Citation Count: 4
  • Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity
    2021
    Summary Details
    OPEN
    Title: Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity
    Author(s): Tae‐Eun Kim, Andrew J. Newman, Thibaut Imberdis, Lisa Brontesi, Arati Tripathi, Nagendran Ramalingam, Saranna Fanning, Dennis J. Selkoe, Ulf Dettmer
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol: 30
    Issue #: 23
    Start Page: 2332
    End Page: 2346
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/hmg/ddab188
    Best OA location URL: https://academic.oup.com/hmg/article-pdf/30/23/2332/41163809/ddab188.pdf
    Citation Count: 11
  • Allosteric Inhibition of Parkinson’s-Linked LRRK2 by Constrained Peptides
    2021
    Summary Details
    OPEN
    Title: Allosteric Inhibition of Parkinson’s-Linked LRRK2 by Constrained Peptides
    Author(s): Leah G. Helton, Ahmed Soliman, Felix von Zweydorf, Michalis Kentros, Jascha T. Manschwetus, Scotty Hall, Bernd K. Gilsbach, Franz Y. Ho, Panagiotis S. Athanasopoulos, Ranjan K. Singh, Timothy J. LeClair, Wim Versées, Francesco Raimondi, Friedrich W. Herberg, Christian Johannes Gloeckner, Hardy J. Rideout, Arjan Kortholt, Eileen J. Kennedy
    Journal Name: ACS Chemical Biology
    Publisher: American Chemical Society (ACS)
    Vol: 16
    Issue #: 11
    Start Page: 2326
    End Page: 2338
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1021/acschembio.1c00487
    Best OA location URL: http://hdl.handle.net/11384/113486
    Citation Count: 36
  • Stimulation-induced reversed plus-minus syndrome: Insights into eyelid physiology
    2018
    Summary Details
    RESTRICTED
    Title: Stimulation-induced reversed plus-minus syndrome: Insights into eyelid physiology
    Author(s): Derrick Soh, Musleh Algarni, Agnes Wong, Andrés M. Lozano, Alfonso Fasano
    Journal Name: Brain Stimulation
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 4
    Start Page: 951
    End Page: 952
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.brs.2018.04.010
    Citation Count: 3
  • Analysis of DNAJC13 mutations in French-Canadian/French cohort of Parkinson's disease
    2016
    Summary Details
    RESTRICTED
    Title: Analysis of DNAJC13 mutations in French-Canadian/French cohort of Parkinson's disease
    Author(s): Jay P. Ross, Nicolas Dupré, Yves Dauvilliers, Stephanie Strong, Amirthagowri Ambalavanan, Dan Spiegelman, Alexandre Dionne‐Laporte, Emanuelle Pourcher, Mélanie Langlois, Michel Boivin, Claire S. Leblond, Patrick A. Dion, Guy A. Rouleau, Ziv Gan‐Or
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 45
    Issue #:
    Start Page: 212.e13
    End Page: 212.e17
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2016.04.023
    Best OA location URL: http://hdl.handle.net/20.500.11794/13593
    Citation Count: 48
  • P1‐021: Diurnal and intersubject variability of cerebrospinal fluid biomarkers, Aβ‐40/42, alpha‐synuclein and DJ‐1 in healthy volunteers
    2012
    Summary Details
    RESTRICTED
    Title: P1‐021: Diurnal and intersubject variability of cerebrospinal fluid biomarkers, Aβ‐40/42, alpha‐synuclein and DJ‐1 in healthy volunteers
    Author(s): Larry Ereshefsky, Mark Frasier, Mark Yen, Stanford S. Jhee, Kenneth Marek, Peggy Taylor, Molly Hamilton Sherman, Chelsea Caspell, Christopher S. Coffey, Michael G. Schlossmacher, Todd Sherer
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol: 8
    Issue #: 4S_Part_3
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.jalz.2012.05.296
    Citation Count: 0
  • Human cerebral collateral arteriole function in subjects with normal cognition, mild cognitive impairment, and dementia
    2018
    Summary Details
    OPEN
    Title: Human cerebral collateral arteriole function in subjects with normal cognition, mild cognitive impairment, and dementia
    Author(s): Raymond Q. Migrino, Seth Truran, Nina Karamanova, Geidy E. Serrano, Calvin Madrigal, Hannah A. Davies, Jillian Madine, Peter D. Reaven, Thomas G. Beach
    Journal Name: American Journal of Physiology-Heart and Circulatory Physiology
    Publisher: American Physiological Society
    Vol: 315
    Issue #: 2
    Start Page: H284
    End Page: H290
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1152/ajpheart.00206.2018
    Best OA location URL: https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00206.2018
    Citation Count: 13
  • Wearable sensor-driven responsive deep brain stimulation for essential tremor
    2021
    Summary Details
    RESTRICTED
    Title: Wearable sensor-driven responsive deep brain stimulation for essential tremor
    Author(s): Stephanie Cernera, Jose D. Alcantara, Enrico Opri, Jackson Cagle, Robert S. Eisinger, Zachary Boogaart, Leena Pramanik, Madison Kelberman, Bhavana Patel, Kelly D. Foote, Michael S. Okun, Aysegul Gunduz
    Journal Name: Brain Stimulation
    Publisher: Elsevier BV
    Vol: 14
    Issue #: 6
    Start Page: 1434
    End Page: 1443
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.brs.2021.09.002
    Best OA location URL: https://doi.org/10.1016/j.brs.2021.09.002
    Citation Count: 38
  • Parkinson's Disease Gene Screening in Familial Cases from Central and South America
    2024
    Summary Details
    OPEN
    Title: Parkinson's Disease Gene Screening in Familial Cases from Central and South America
    Author(s): Oswaldo Lorenzo Betancor, Seysha Mehta, Janvi Ramchandra, Sekinat Mumuney, Artur F. Schumacher-Schuh, Mario Cornejo‐Olivas, Elison H. Sarapura‐Castro, Luís Torres, Miguel A. Inca-Martínez, Pilar Mazzetti, Carlos Cosentino, Federico Micheli, Vitor Tumas, Elena Dieguez, Victor Raggio, Vanderci Borges, Henrique B. Ferraz, Pedro Chana-Cuevas, Marlene Jimenez-Del-Rio, Carlos Vélez Pardo, Sonia Moreno, Francisco Lopera, Jorge L. Orozco‐Velez, Beatriz Muñoz Ospina, Carlos R M Rieder, Alex Medina Escobar, Dora Yearout, Cyrus P. Zabetian, Ignacio F. Mata, Latin American Research Consortium on the Genetics of PD (LARGE‐PD), Oswaldo Lorenzo Betancor, Janvi Ramchandra, Artur F. Schumacher-Schuh, Mario Cornejo‐Olivas, Elison H. Sarapura‐Castro, Luís Torres, Pilar Mazzetti, Carlos Cosentino, Federico Micheli, Vitor Tumas, Elena Dieguez, Victor Raggio, Vanderci Borges, Henrique B. Ferraz, Pedro Chana-Cuevas, Marlene Jimenez-Del-Rio, Carlos Vélez Pardo, Sonia Moreno, Francisco Lopera, Jorge L. Orozco‐Velez, Beatriz Muñoz Ospina, Carlos R M Rieder, Alex Medina Escobar, Cyrus P. Zabetian, Ignacio F. Mata, Latin American Research Consortium on the Genetics of PD (LARGE‐PD)
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 39
    Issue #: 10
    Start Page: 1843
    End Page: 1855
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mds.29931
    Best OA location URL: https://doi.org/10.1002/mds.29931
    Citation Count: 4
  • Distinct functional roles of Vps41-mediated neuroprotection in Alzheimer’s and Parkinson’s disease models of neurodegeneration
    2018
    Summary Details
    OPEN
    Title: Distinct functional roles of Vps41-mediated neuroprotection in Alzheimer’s and Parkinson’s disease models of neurodegeneration
    Author(s): Edward F. Griffin, Xiaohui Yan, Kim A. Caldwell, Guy A. Caldwell
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddy308
    Citation Count: 30
  • Reduced complement of dopaminergic neurons in the substantia nigra pars compacta of mice with a constitutive “low footprint” genetic knockout of alpha-synuclein
    2020
    Summary Details
    OPEN
    Title: Reduced complement of dopaminergic neurons in the substantia nigra pars compacta of mice with a constitutive “low footprint” genetic knockout of alpha-synuclein
    Author(s): Valeria Goloborshcheva, Kirill Chaprov, Е. В. Тетерина, Ruslan Ovchinnikov, Vladimir L. Buchman
    Journal Name: Molecular Brain
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13041-020-00613-5
    Best OA location URL: https://molecularbrain.biomedcentral.com/track/pdf/10.1186/s13041-020-00613-5
    Citation Count: 11
  • Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain
    2018
    Summary Details
    OPEN
    Title: Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain
    Author(s): Wenze Niu, Tong Zang, Lei-Lei Wang, Yuhua Zou, Chunli Zhang
    Journal Name: Stem Cell Reports
    Publisher: Elsevier BV
    Vol: 11
    Issue #: 5
    Start Page: 1156
    End Page: 1170
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.stemcr.2018.09.004
    Best OA location URL: http://www.cell.com/article/S2213671118303898/pdf
    Citation Count: 43
  • Small Molecule Improvement of Trafficking Defects in Models of Neurodegeneration
    2021
    Summary Details
    OPEN
    Title: Small Molecule Improvement of Trafficking Defects in Models of Neurodegeneration
    Author(s): A. Katherine Hatstat, Michael D. Pupi, Michaela C. Reinhart, Dewey G. McCafferty
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 12
    Issue #: 21
    Start Page: 3972
    End Page: 3984
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.1c00524
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9754116
    Citation Count: 1
  • PINK 1 autophosphorylation is required for ubiquitin recognition
    2018
    Summary Details
    OPEN
    Title: PINK 1 autophosphorylation is required for ubiquitin recognition
    Author(s): Shafqat Rasool, Naoto Soya, Luc Truong, Nathalie Croteau, Gergely L. Lukács, Jean‐François Trempe
    Journal Name: EMBO reports
    Publisher: Springer Science and Business Media LLC
    Vol: 19
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.15252/embr.201744981
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.201744981
    Citation Count: 107
  • No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson’s disease
    2017
    Summary Details
    OPEN
    Title: No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson’s disease
    Author(s): Johannes Jernqvist Gaare, Gonzalo S. Nido, Paweł Sztromwasser, Per M. Knappskog, Olav Dahl, Morten Lund‐Johansen, Guido Alves, Ole‐Bjørn Tysnes, Stefan Johansson, Kristoffer Haugarvoll, Charalampos Tzoulis
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 141
    Issue #: 3
    Start Page: e16
    End Page: e16
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1093/brain/awx378
    Best OA location URL: https://academic.oup.com/brain/article-pdf/141/3/e16/25046297/awx378.pdf
    Citation Count: 8
  • Personality and reported quality of life in Parkinson's disease
    2016
    Summary Details
    OPEN
    Title: Personality and reported quality of life in Parkinson's disease
    Author(s): Gregory M. Pontone, Zoltán Mari, Kate Perepezko, Howard D. Weiss, Susan Spear Bassett
    Journal Name: International Journal of Geriatric Psychiatry
    Publisher: Wiley
    Vol: 32
    Issue #: 3
    Start Page: 324
    End Page: 330
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/gps.4475
    Best OA location URL: http://doi.org/10.1002/gps.4475
    Citation Count: 24
  • A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson's Research
    2013
    Summary Details
    OPEN
    Title: A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson's Research
    Author(s): Marco A. S. Baptista, Kuldip D. Dave, Niketa P. Sheth, Shehan N. De Silva, Kirsten Matoy Carlson, Yasmin Aziz, Brian Fiske, Todd Sherer, Mark Frasier
    Journal Name: Disease Models & Mechanisms
    Publisher: The Company of Biologists
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1242/dmm.011940
    Best OA location URL: https://doi.org/10.1242/dmm.011940
    Citation Count: 37
  • Feasibility and Safety of Multisite Tissue and Biofluid Sampling for Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4) (P1.013)
    2017
    Summary Details
    RESTRICTED
    Title: Feasibility and Safety of Multisite Tissue and Biofluid Sampling for Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4) (P1.013)
    Author(s): Carly Linder, Christopher S. Coffey, Thomas G. Beach, Tatiana Foroud, Charles H. Adler, Holly Riss, Dixie Ecklund, Chelsea Caspell‐Garcia, Kuldip D. Dave, Sampada Deshpande, Shirley Lasch, Vanessa Arnedo, Lindsey Riley, Danna Jennings, Brit Mollenhauer, Lana M. Chahine
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 88
    Issue #: 16_supplement
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.88.16_supplement.p1.013
    Citation Count: 0
  • Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum
    2018
    Summary Details
    OPEN
    Title: Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum
    Author(s): Ellie-Anna Minogianis, Waqqas M. Shams, Omar S. Mabrouk, Jenny‐Marie T. Wong, Wayne G. Brake, Robert T. Kennedy, Patrick du Souich, Anne‐Noël Samaha
    Journal Name: European Journal of Neuroscience
    Publisher: Wiley
    Vol: 50
    Issue #: 3
    Start Page: 2054
    End Page: 2064
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ejn.13941
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ejn.13941
    Citation Count: 20
  • Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2
    2012
    Summary Details
    RESTRICTED
    Title: Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2
    Author(s): Renée Vancraenenbroeck, Evy Lobbestael, S.D. Weeks, Sergei V. Strelkov, Veerle Baekelandt, Jean‐Marc Taymans, Marc De Maeyer
    Journal Name: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
    Publisher: Elsevier BV
    Vol: 1824
    Issue #: 3
    Start Page: 450
    End Page: 460
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.bbapap.2011.12.009
    Citation Count: 26
  • Biomarkers in Parkinson‘s Disease: A Funder‘s Perspective
    2010
    Summary Details
    RESTRICTED
    Title: Biomarkers in Parkinson‘s Disease: A Funder‘s Perspective
    Author(s): Mark Frasier, Sohini Chowdhury, Jamie L. Eberling, Todd Sherer
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 5
    Start Page: 723
    End Page: 729
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.89
    Citation Count: 17
  • Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson′s Disease
    2022
    Summary Details
    OPEN
    Title: Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson′s Disease
    Author(s): Ilda Coku, Eugénie Mutez, Sabiha Eddarkaoui, Sébastien Carrier, Antoine Marchand, Claire Deldycke, Liesel Goveas, Guillaume Baille, Mélissa Tir, Romain Magnez, Xavier Thuru, Gaëlle Vermeersch, Wim Vandenberghe, Luc Buée, Luc Defebvre, Bernard Sablonnière, Marie‐Christine Chartier‐Harlin, Jean‐Marc Taymans, Vincent Huin
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 37
    Issue #: 8
    Start Page: 1761
    End Page: 1767
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mds.29124
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29124
    Citation Count: 7
  • 14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening
    2015
    Summary Details
    OPEN
    Title: 14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening
    Author(s): Nicholas J. Lavalley, Sunny R. Slone, Huiping Ding, Andrew B. West, Talene A. Yacoubian
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol: 25
    Issue #: 1
    Start Page: 109
    End Page: 122
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddv453
    Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/1/109/7145789/ddv453.pdf
    Citation Count: 78
  • Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration
    2022
    Summary Details
    OPEN
    Title: Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration
    Author(s): Raquel Gómez‐Sintes, Qisheng Xin, Juan Ignacio Jiménez‐Loygorri, Mericka McCabe, Antonio Díaz, Thomas P. Garner, Xiomaris M. Cotto-Rios, Yang‐Chang Wu, Shuxian Dong, Cara A. Reynolds, Bindi Patel, Pedro de la Villa, Fernando Macián, Patricia Boya, Evripidis Gavathiotis, Ana María Cuervo
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-022-31869-1
    Best OA location URL: https://www.nature.com/articles/s41467-022-31869-1.pdf
    Citation Count: 39
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