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  • Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
    2012
    Summary Details
    OPEN
    Title: Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
    Author(s): Houbo Jiang, Yong Ren, Eunice Y. Yuen, Ping Zhong, Mahboobe Ghaedi, Zhixing Hu, Gissou Azabdaftari, Kazuhiro Nakaso, Zhen Yan, Jian Feng
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 3
    Issue #: 1
    Start Page: 668
    End Page: 668
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ncomms1669
    Best OA location URL: https://www.nature.com/articles/ncomms1669.pdf
    Citation Count: 252
  • Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons
    2014
    Summary Details
    OPEN
    Title: Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons
    Author(s): Nicholas C. Flytzanis, Claire N. Bedbrook, Hui Chiu, Martin K. M. Engqvist, Cheng Xiao, Ken Y. Chan, Paul W. Sternberg, Frances H. Arnold, Viviana Gradinaru
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 5
    Issue #: 1
    Start Page: 4894
    End Page: 4894
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ncomms5894
    Best OA location URL: https://www.nature.com/articles/ncomms5894.pdf
    Citation Count: 144
  • α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
    2009
    Summary Details
    OPEN
    Title: α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
    Author(s): Aaron D. Gitler, Alessandra Chesi, Melissa L. Geddie, Katherine E. Strathearn, Shusei Hamamichi, Kathryn J. Hill, Kim A. Caldwell, Guy A. Caldwell, Antony A. Cooper, Jean‐Christophe Rochet, Susan Lindquist
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Vol: 41
    Issue #: 3
    Start Page: 308
    End Page: 315
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ng.300
    Best OA location URL: http://doi.org/10.1038/ng.300
    Citation Count: 537
  • Therapeutic cloning in individual parkinsonian mice
    2008
    Summary Details
    OPEN
    Title: Therapeutic cloning in individual parkinsonian mice
    Author(s): Viviane Tabar, Mark Tomishima, Georgia Panagiotakos, Sayaka Wakayama, Jayanthi Menon, Bill Chan, Eiji Mizutani, George Al-Shamy, Hiroshi Ohta, Teruhiko Wakayama, Lorenz Studer
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 4
    Start Page: 379
    End Page: 381
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nm1732
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2786166
    Citation Count: 116
  • Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
    2010
    Summary Details
    OPEN
    Title: Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
    Author(s): Byoung Dae Lee, Joo‐Ho Shin, Jackalina VanKampen, Leonard Petrucelli, Andrew B. West, Han Seok Ko, Yun-Il Lee, Kathleen A. Maguire‐Zeiss, William J. Bowers, Howard J. Federoff, Valina L. Dawson, Ted M. Dawson
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 9
    Start Page: 998
    End Page: 1000
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nm.2199
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2935926
    Citation Count: 382
  • MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration
    2014
    Summary Details
    OPEN
    Title: MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration
    Author(s): Carolina Cebrián, Fabio A. Zucca, Pierluigi Mauri, Julius A. Steinbeck, Lorenz Studer, Clemens R. Scherzer, Ellen Kanter, Sadna Budhu, Jonathan Mandelbaum, Jean Paul Vonsattel, Luigi Zecca, John D. Loike, David Sulzer
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 5
    Issue #: 1
    Start Page: 3633
    End Page: 3633
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ncomms4633
    Best OA location URL: https://www.nature.com/articles/ncomms4633.pdf
    Citation Count: 334
  • HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease
    2010
    Summary Details
    OPEN
    Title: HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease
    Author(s): C. Savio Chan, Kelly E. Glajch, Tracy S. Gertler, Jaime N. Guzmán, Jeff Mercer, Alan S. Lewis, Alan B Goldberg, Tatiana Tkatch, Ryuichi Shigemoto, Sheila M. Fleming, Dane M. Chetkovich, Pavel Osten, Hitoshi Kita, D. James Surmeier
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 1
    Start Page: 85
    End Page: 92
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2692
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3058391
    Citation Count: 183
  • Subthalamic nucleus stimulation reverses mediofrontal influence over decision threshold
    2011
    Summary Details
    RESTRICTED
    Title: Subthalamic nucleus stimulation reverses mediofrontal influence over decision threshold
    Author(s): James F. Cavanagh, Thomas V. Wiecki, Michael X Cohen, Christina M. Figueroa, Johan Samanta, Scott J. Sherman, Michael J. Frank
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 11
    Start Page: 1462
    End Page: 1467
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2925
    Citation Count: 683
  • Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
    2010
    Summary Details
    OPEN
    Title: Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
    Author(s): Taye H. Hamza, Cyrus P. Zabetian, Albert Tenesa, Alain Laederach, Jennifer S. Montimurro, Dora Yearout, Denise M. Kay, Kimberly F. Doheny, Justin Paschall, Elizabeth Pugh, Victoria I. Kusel, Randall V. Collura, John W. Roberts, Alida Griffith, Ali Samii, William K. Scott, John G. Nutt, Stewart A. Factor, Haydeh Payami
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Vol: 42
    Issue #: 9
    Start Page: 781
    End Page: 785
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ng.642
    Best OA location URL: http://hdl.handle.net/20.500.11820/b0e35720-bc0d-43af-818b-6597947a050f
    Citation Count: 810
  • Essential function of HIPK2 in TGFβ-dependent survival of midbrain dopamine neurons
    2006
    Summary Details
    RESTRICTED
    Title: Essential function of HIPK2 in TGFβ-dependent survival of midbrain dopamine neurons
    Author(s): Jiasheng Zhang, Vanee Pho, Stephen J. Bonasera, Jed Holtzman, Amy T Tang, Joanna Hellmuth, Siuwah Tang, Patricia H. Janak, Laurence H. Tecott, Eric J. Huang
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page: 77
    End Page: 86
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nn1816
    Citation Count: 135
  • Interplay of LRRK2 with chaperone-mediated autophagy
    2013
    Summary Details
    RESTRICTED
    Title: Interplay of LRRK2 with chaperone-mediated autophagy
    Author(s): Samantha J. Orenstein, Sheng‐Han Kuo, Inmaculada Tasset, Esperanza Arias, Hiroshi Koga, Irene Fernández‐Carasa, Etty Cortés, Lawrence S. Honig, William T. Dauer, Antonella Consiglio, Ángel Raya, David Sulzer, Ana María Cuervo
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 4
    Start Page: 394
    End Page: 406
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3350
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3609872
    Citation Count: 578
  • CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
    2013
    Summary Details
    OPEN
    Title: CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
    Author(s): Brian C. Shonesy, Xiaohan Wang, Kristie L. Rose, Teniel S Ramikie, Victoria S. Cavener, Tyler J. Rentz, Anthony J. Baucum, Nidhi Jalan‐Sakrikar, Ken Mackie, Danny G. Winder, Sachin Patel, Roger Colbran
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 4
    Start Page: 456
    End Page: 463
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3353
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3636998
    Citation Count: 82
  • Mind matters: placebo enhances reward learning in Parkinson's disease
    2014
    Summary Details
    OPEN
    Title: Mind matters: placebo enhances reward learning in Parkinson's disease
    Author(s): Liane Schmidt, Erin Kendall Braun, Tor D. Wager, Daphna Shohamy
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 17
    Issue #: 12
    Start Page: 1793
    End Page: 1797
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3842
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4503317
    Citation Count: 82
  • Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum
    2016
    Summary Details
    RESTRICTED
    Title: Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum
    Author(s): Daniela Baptista, Yvonne Schmitz, József Mészáros, Paolomi Merchant, Gang Hu, Shu Li, Adam Henke, José E. Lizardi-Ortiz, Richard J. Karpowicz, Travis J. Morgenstern, Mark S. Sonders, Ellen Kanter, Pamela C. Rodriguez, Eugene V. Mosharov, Dalibor Sameš, David Sulzer
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 19
    Issue #: 4
    Start Page: 578
    End Page: 586
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nn.4252
    Citation Count: 183
  • A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    2018
    Summary Details
    OPEN
    Title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    Author(s): Hongjun Fu, Andrea Possenti, Rosie Freer, Yoshikazu Nakano, Nancy C. Hernandez Villegas, Maoping Tang, Paula Victoria Maglio Cauhy, Benjamin Lassus, Shuo Chen, Stephanie L. Fowler, Helen Y. Figueroa, Edward D. Huey, Gail V.W. Johnson, Michele Vendruscolo, Karen Duff
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 22
    Issue #: 1
    Start Page: 47
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7
    Citation Count: 273
  • Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
    2009
    Summary Details
    OPEN
    Title: Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
    Author(s): Yanping Li, Wencheng Liu, Tinmarla F. Oo, Lei Wang, Yi Ling Tang, Vernice Jackson‐Lewis, Chun Hui Zhou, Kindiya D. Geghman, Mikhail Bogdanov, Serge Przedborski, M. Flint Beal, Robert E. Burke, Chenjian Li
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 7
    Start Page: 826
    End Page: 828
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2349
    Best OA location URL: http://doi.org/10.1038/nn.2349
    Citation Count: 538
  • A causal link between prediction errors, dopamine neurons and learning
    2013
    Summary Details
    OPEN
    Title: A causal link between prediction errors, dopamine neurons and learning
    Author(s): Elizabeth E. Steinberg, Ronald Keiflin, Josiah R. Boivin, Ilana B. Witten, Karl Deisseroth, Patricia H. Janak
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 16
    Issue #: 7
    Start Page: 966
    End Page: 973
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.3413
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3705924
    Citation Count: 936
  • Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
    2015
    Summary Details
    RESTRICTED
    Title: Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
    Author(s): Jennifer B. Treweek, Ken Y. Chan, Nicholas C. Flytzanis, Bin Yang, Benjamin E. Deverman, Alon Greenbaum, Antti Lignell, Cheng Xiao, Long Cai, Mark S. Ladinsky, Pamela J. Björkman, Charless C. Fowlkes, Viviana Gradinaru
    Journal Name: Nature Protocols
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 11
    Start Page: 1860
    End Page: 1896
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nprot.2015.122
    Citation Count: 274
  • Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI
    2017
    Summary Details
    OPEN
    Title: Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI
    Author(s): Anupama Lakshmanan, George J. Lu, Arash Farhadi, Suchita P. Nety, Martin Kunth, Audrey Lee‐Gosselin, David Maresca, Raymond W. Bourdeau, Melissa Yin, Judy Yan, Christopher Witte, Dina Malounda, F. Stuart Foster, Leif Schröder, Mikhail G. Shapiro
    Journal Name: Nature Protocols
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 10
    Start Page: 2050
    End Page: 2080
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nprot.2017.081
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6185898
    Citation Count: 180
  • MRI biomarkers — a precision medicine tool in neurology?
    2016
    Summary Details
    RESTRICTED
    Title: MRI biomarkers — a precision medicine tool in neurology?
    Author(s): А В Березин, Н С Келлин, М Б Марков, С В Паротькин
    Journal Name: Nature Reviews Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 6
    Start Page: 323
    End Page: 4
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nrneurol.2016.51
    Citation Count: 0
  • Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    2017
    Summary Details
    OPEN
    Title: Mechanism and regulation of the Lys6-selective deubiquitinase USP30
    Author(s): Malte Gersch, Christina Gladkova, Alexander F. Schubert, Martin A. Michel, Sarah Maslen, David Komander
    Journal Name: Nature Structural & Molecular Biology
    Publisher: Springer Science and Business Media LLC
    Vol: 24
    Issue #: 11
    Start Page: 920
    End Page: 930
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nsmb.3475
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5757785
    Citation Count: 223
  • UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals
    2008
    Summary Details
    RESTRICTED
    Title: UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals
    Author(s): Zane B. Andrews, Liu Hon, Nicholas Walllingford, Derek M. Erion, Erzsébet Borók, Jeffery M. Friedman, Matthias H. Tschöp, Marya Shanabrough, Gary W. Cline, Gerald I. Shulman, Anna Coppola, Xiao‐Bing Gao, Tamás L. Horváth, Sabrina Diano
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 454
    Issue #: 7206
    Start Page: 846
    End Page: 851
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nature07181
    Citation Count: 698
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 397
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 189
  • Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    2013
    Summary Details
    OPEN
    Title: Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    Author(s): Shireen A. Sarraf, Malavika Raman, Virginia Guarani‐Pereira, Mathew E. Sowa, Edward L. Huttlin, Steven P. Gygi, J. Wade Harper
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 496
    Issue #: 7445
    Start Page: 372
    End Page: 376
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature12043
    Best OA location URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11878916
    Citation Count: 1020
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