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  • Activation mechanism of PINK1
    2021
    Summary Details
    OPEN
    Title: Activation mechanism of PINK1
    Author(s): Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 602
    Issue #: 7896
    Start Page: 328
    End Page: 335
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-04340-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8828467
    Citation Count: 190
  • Brain-restricted mTOR inhibition with binary pharmacology
    2022
    Summary Details
    OPEN
    Title: Brain-restricted mTOR inhibition with binary pharmacology
    Author(s): Ziyang Zhang, Qi-Wen Fan, Xujun Luo, Kevin Lou, William A. Weiss, Kevan M. Shokat
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 609
    Issue #: 7928
    Start Page: 822
    End Page: 828
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41586-022-05213-y
    Best OA location URL: https://www.nature.com/articles/s41586-022-05213-y.pdf
    Citation Count: 81
  • UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals
    2008
    Summary Details
    RESTRICTED
    Title: UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals
    Author(s): Zane B. Andrews, Liu Hon, Nicholas Walllingford, Derek M. Erion, Erzsébet Borók, Jeffery M. Friedman, Matthias H. Tschöp, Marya Shanabrough, Gary W. Cline, Gerald I. Shulman, Anna Coppola, Xiao‐Bing Gao, Tamás L. Horváth, Sabrina Diano
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 454
    Issue #: 7206
    Start Page: 846
    End Page: 851
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nature07181
    Citation Count: 698
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 397
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 189
  • Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    2013
    Summary Details
    OPEN
    Title: Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    Author(s): Shireen A. Sarraf, Malavika Raman, Virginia Guarani‐Pereira, Mathew E. Sowa, Edward L. Huttlin, Steven P. Gygi, J. Wade Harper
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 496
    Issue #: 7445
    Start Page: 372
    End Page: 376
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature12043
    Best OA location URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11878916
    Citation Count: 1020
  • Disruption of mitochondrial complex I induces progressive parkinsonism
    2021
    Summary Details
    OPEN
    Title: Disruption of mitochondrial complex I induces progressive parkinsonism
    Author(s): Patricia González‐Rodríguez, Enrico Zampese, Kristen A. Stout, Jaime N. Guzmán, Ema Ilijić, Ben Yang, Tatiana Tkatch, Mihaela Stavarache, David L. Wokosin, Lin Gao, Michael G. Kaplitt, José López‐Barneo, Paul T. Schumacker, D. James Surmeier
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 599
    Issue #: 7886
    Start Page: 650
    End Page: 656
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-04059-0
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9189968
    Citation Count: 532
  • Within-host evolution of a gut pathobiont facilitates liver translocation
    2022
    Summary Details
    OPEN
    Title: Within-host evolution of a gut pathobiont facilitates liver translocation
    Author(s): Yi Yang, Mytien Nguyen, Varnica Khetrapal, Nicole Sonnert, Anjelica Martin, Haiwei Chen, Martin Kriegel, Noah W. Palm
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 607
    Issue #: 7919
    Start Page: 563
    End Page: 570
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-022-04949-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9308686
    Citation Count: 158
  • Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    2009
    Summary Details
    OPEN
    Title: Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    Author(s): Kambiz N. Alavian, Paola Sgadó, Lavinia Albéri, Srinivasa Subramaniam, Horst H. Simon
    Journal Name: Neural Development
    Publisher: Springer Science and Business Media LLC
    Vol: 4
    Issue #: 1
    Start Page: 11
    End Page: 11
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1749-8104-4-11
    Best OA location URL: https://neuraldevelopment.biomedcentral.com/counter/pdf/10.1186/1749-8104-4-11
    Citation Count: 41
  • Microglial responses to dopamine in a cell culture model of Parkinson's disease
    2008
    Summary Details
    RESTRICTED
    Title: Microglial responses to dopamine in a cell culture model of Parkinson's disease
    Author(s): Diego Mastroeni, Andrew Grover, Brian Leonard, Jeffrey N. Joyce, Paul D. Coleman, Brooke Kozik, Denise L. Bellinger, Joseph Rogers
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 30
    Issue #: 11
    Start Page: 1805
    End Page: 1817
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2008.01.001
    Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2008.01.001
    Citation Count: 140
  • Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease
    2013
    Summary Details
    OPEN
    Title: Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease
    Author(s): Margarita Giraldo, Francisco Lopera, Ashley L. Siniard, Jason J. Corneveaux, Isabelle Schrauwen, Julian Carvajal, Claudia Muñoz, Manuel Ramirez‐Restrepo, Chris Gaiteri, Amanda Myers, Richard J. Caselli, Kenneth S. Kosik, Eric M. Reiman, Matthew J. Huentelman
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 34
    Issue #: 8
    Start Page: 2077.e11
    End Page: 2077.e18
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.02.016
    Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2013.02.016
    Citation Count: 145
  • Mutational analysis of parkin and PINK1 in multiple system atrophy
    2010
    Summary Details
    OPEN
    Title: Mutational analysis of parkin and PINK1 in multiple system atrophy
    Author(s): Janet Brooks, Henry Houlden, Anna Melchers, Ansha J. Islam, Jinhui Ding, Abi Li, Reema Paudel, Tamás Révész, Janice L. Holton, Nick Wood, Andrew J. Lees, Andrew Singleton, Sonja W. Scholz
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 32
    Issue #: 3
    Start Page: 548.e5
    End Page: 548.e7
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2009.11.020
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3934211
    Citation Count: 21
  • Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
    2015
    Summary Details
    OPEN
    Title: Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
    Author(s): Diego Mastroeni, Elaine Delvaux, Jennifer Nolz, Yuyan Tan, Andrew Grover, Salvatore Oddo, Paul D. Coleman
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 12
    Start Page: 3121
    End Page: 3129
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.08.017
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4838454
    Citation Count: 61
  • Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions
    2014
    Summary Details
    OPEN
    Title: Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansions
    Author(s): Sonja W. Scholz, Elisa Majounie, Tamás Révész, Janice L. Holton, Michael S. Okun, Henry Houlden, Andrew Singleton
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 2
    Start Page: 1223.e1
    End Page: 1223.e2
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2014.08.033
    Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2014.08.033
    Citation Count: 30
  • Isolation and characterization of antibody fragments selective for toxic oligomeric tau
    2014
    Summary Details
    OPEN
    Title: Isolation and characterization of antibody fragments selective for toxic oligomeric tau
    Author(s): Huilai Tian, Eliot J. Davidowitz, Patricia López, Ping He, Philip Schulz, James G. Moe, Michael R. Sierks
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 36
    Issue #: 3
    Start Page: 1342
    End Page: 1355
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2014.12.002
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4346425
    Citation Count: 27
  • MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials
    2015
    Summary Details
    OPEN
    Title: MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials
    Author(s): Xue Hua, Christopher R. K. Ching, Adam Mezher, Boris A. Gutman, Derrek P. Hibar, Priya Bhatt, Alex Leow, Clifford R. Jack, Matt A. Bernstein, Michael W. Weiner, Paul M. Thompson
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 37
    Issue #:
    Start Page: 26
    End Page: 37
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.09.018
    Best OA location URL: https://www.sciencedirect.com/science/article/am/pii/S0197458015004753
    Citation Count: 50
  • Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1
    2017
    Summary Details
    OPEN
    Title: Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1
    Author(s): Miao Sun, Huaye Zhang
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 60
    Issue #:
    Start Page: 129
    End Page: 140
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2017.08.024
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5653456
    Citation Count: 28
  • Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology
    2017
    Summary Details
    RESTRICTED
    Title: Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology
    Author(s): Douglas G. Walker, Lih‐Fen Lue, Tiffany M. Tang, Charles H. Adler, John N. Caviness, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Thomas G. Beach
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 54
    Issue #:
    Start Page: 175
    End Page: 186
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2017.03.007
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5862548
    Citation Count: 34
  • Sequencing of the GBA coactivator, Saposin C, in Parkinson disease
    2018
    Summary Details
    RESTRICTED
    Title: Sequencing of the GBA coactivator, Saposin C, in Parkinson disease
    Author(s): Bouchra Ouled Amar Bencheikh, Etienne Léveillé, Jennifer A. Ruskey, Dan Spiegelman, Christopher Liong, Edward A. Fon, Guy A. Rouleau, Yves Dauvilliers, Nicolas Dupré, Roy N. Alcalay, Ziv Gan‐Or
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 72
    Issue #:
    Start Page: 187.e1
    End Page: 187.e3
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2018.06.034
    Citation Count: 29
  • Genetic analysis of neurodegenerative diseases in a pathology cohort
    2018
    Summary Details
    RESTRICTED
    Title: Genetic analysis of neurodegenerative diseases in a pathology cohort
    Author(s): Cornelis Blauwendraat, Olga Pletniková, Joshua T. Geiger, Natalie A. Murphy, Yevgeniya Abramzon, Gay Rudow, Adamantios Mamais, Marya S. Sabir, Barbara J. Crain, Sarah Ahmed, Liana S. Rosenthal, Catherine C. Bakker, Faraz Faghri, Ruth Chia, Jinhui Ding, Ted M. Dawson, Alexander Pantelyat, Marilyn S. Albert, Mike A. Nalls, Susan M. Resnick, Luigi Ferrucci, Mark Cookson, Argye E. Hillis, Juan C. Troncoso, Sonja W. Scholz
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 76
    Issue #:
    Start Page: 214.e1
    End Page: 214.e9
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2018.11.007
    Citation Count: 51
  • Identification of Drugs Associated with Lower Risk of Parkinson’s Disease Using a Systematic Screening Approach in a Nationwide Nested Case–Control Study
    2022
    Summary Details
    OPEN
    Title: Identification of Drugs Associated with Lower Risk of Parkinson’s Disease Using a Systematic Screening Approach in a Nationwide Nested Case–Control Study
    Author(s): Marjaana Koponen, Anne Paakinaho, Julian Lin, Sirpa Hartikainen, Anna‐Maija Tolppanen
    Journal Name: Clinical Epidemiology
    Publisher: Informa UK Limited
    Vol: Volume 14
    Issue #:
    Start Page: 1217
    End Page: 1227
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.2147/clep.s381289
    Best OA location URL: https://www.dovepress.com/getfile.php?fileID=84998
    Citation Count: 13
  • Prevalence of hippocampal sclerosis in a clinicopathologically characterized cohort
    2013
    Summary Details
    OPEN
    Title: Prevalence of hippocampal sclerosis in a clinicopathologically characterized cohort
    Author(s): Michael Malek‐Ahmadi, Vickram Kahlon, Charles H. Adler, Aleksandra Obradov, Kabir Thind, Holly A. Shill, Lucia I. Sue, John N. Caviness, Sandra A. Jacobson, Marwan N. Sabbagh
    Journal Name: Clinical and Experimental Medical Sciences
    Publisher: Hikari, Ltd.
    Vol:
    Issue #:
    Start Page: 317
    End Page: 327
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.12988/cems.2013.13026
    Best OA location URL: https://doi.org/10.12988/cems.2013.13026
    Citation Count: 9
  • Sarcopenia and impairment in cognitive and physical performance
    2015
    Summary Details
    OPEN
    Title: Sarcopenia and impairment in cognitive and physical performance
    Author(s): Magdalena I. Tolea, James E. Galvin
    Journal Name: Clinical Interventions in Aging
    Publisher: Informa UK Limited
    Vol:
    Issue #:
    Start Page: 663
    End Page: 663
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.2147/cia.s76275
    Best OA location URL: https://www.dovepress.com/getfile.php?fileID=24358
    Citation Count: 111
  • Correlates of deep brain stimulation consensus conference decision to treat primary dystonia
    2021
    Summary Details
    OPEN
    Title: Correlates of deep brain stimulation consensus conference decision to treat primary dystonia
    Author(s): Lindsay Niccolai, Stephen L. Aita, Harrison C. Walker, Victor A. Del Bene, Adam Gerstenecker, Dario Marotta, Meredith Gammon, Roy C. Martin, Olivio J. Clay, Michael Crowe, Kristen Triebel
    Journal Name: Clinical Neurology and Neurosurgery
    Publisher: Elsevier BV
    Vol: 207
    Issue #:
    Start Page: 106747
    End Page: 106747
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.clineuro.2021.106747
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8386520
    Citation Count: 9
  • Early subthalamic nucleus deep brain stimulation in Parkinson’s disease reduces long-term medication costs
    2021
    Summary Details
    OPEN
    Title: Early subthalamic nucleus deep brain stimulation in Parkinson’s disease reduces long-term medication costs
    Author(s): Mallory L. Hacker, Grace Cannard, Maxim Turchan, Jacqueline Meystedt, Thomas L. Davis, Fenna T. Phibbs, Peter Hedera, Peter E. Konrad, David Charles
    Journal Name: Clinical Neurology and Neurosurgery
    Publisher: Elsevier BV
    Vol: 210
    Issue #:
    Start Page: 106976
    End Page: 106976
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.clineuro.2021.106976
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8608728
    Citation Count: 10
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