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  • Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylases
    2016
    Summary Details
    OPEN
    Title: Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylases
    Author(s): R. Foti, Philippe Diaz, Dominique Douguet
    Journal Name: Journal of Enzyme Inhibition and Medicinal Chemistry
    Publisher: Informa UK Limited
    Vol: 31
    Issue #: sup2
    Start Page: 148
    End Page: 161
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1080/14756366.2016.1193734
    Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/14756366.2016.1193734?needAccess=true
    Citation Count: 12
  • A novel neuroprotective therapy for Parkinson’s disease using a viral noncoding RNA that protects mitochondrial Complex I activity
    2011
    Summary Details
    OPEN
    Title: A novel neuroprotective therapy for Parkinson’s disease using a viral noncoding RNA that protects mitochondrial Complex I activity
    Author(s): Wei‐Li Kuan, Emma Poole, Michael Fletcher, Sharon Karniely, Pam Tyers, Mark R. Wills, Roger A. Barker, John Sinclair
    Journal Name: Journal of Experimental Medicine
    Publisher: Rockefeller University Press
    Vol: 209
    Issue #: 1
    Start Page: 1
    End Page: 10
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1084/jem.20111126
    Best OA location URL: http://jem.rupress.org/content/jem/209/1/1.full.pdf
    Citation Count: 37
  • LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection
    2017
    Summary Details
    OPEN
    Title: LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection
    Author(s): Weiwei Liu, Xianan Liu, Yu Li, Junjie Zhao, Zhenshan Liu, Zhuqin Hu, Ying Wang, Yufeng Yao, Aaron W. Miller, Bing Su, Mark Cookson, Xiaoxia Li, Zizhen Kang
    Journal Name: Journal of Experimental Medicine
    Publisher: Rockefeller University Press
    Vol: 214
    Issue #: 10
    Start Page: 3051
    End Page: 3066
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-sa
    DOI - Digital Object Identifier: 10.1084/jem.20170014
    Best OA location URL: https://rupress.org/jem/article-pdf/214/10/3051/1166015/jem_20170014.pdf
    Citation Count: 166
  • Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
    2010
    Summary Details
    OPEN
    Title: Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
    Author(s): Rahul Srinivasan, Rigo Pantoja, Fraser J. Moss, Elisha D.W. Mackey, Çağdaş Devrim Son, Julie M. Miwa, Henry A. Lester
    Journal Name: Journal of General Physiology
    Publisher: Rockefeller University Press
    Vol: 137
    Issue #: 1
    Start Page: 59
    End Page: 79
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1085/jgp.201010532
    Best OA location URL: https://rupress.org/jgp/article-pdf/137/1/59/1187438/jgp_201010532.pdf
    Citation Count: 165
  • Interest in Genetic Testing in Ashkenazi Jewish Parkinson's Disease Patients and Their Unaffected Relatives
    2014
    Summary Details
    OPEN
    Title: Interest in Genetic Testing in Ashkenazi Jewish Parkinson's Disease Patients and Their Unaffected Relatives
    Author(s): Manisha Gupte, Roy N. Alcalay, Helen Mejia‐Santana, Deborah Raymond, Rachel Saunders‐Pullman, Ernest Roos, Martha Orbe‐Reily, Ming‐X Tang, Anat Mirelman, Laurie J. Ozelius, Avi Orr‐Urtreger, Lorraine N. Clark, Nir Giladi, Susan Bressman, Karen Marder
    Journal Name: Journal of Genetic Counseling
    Publisher: Wiley
    Vol: 24
    Issue #: 2
    Start Page: 238
    End Page: 246
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s10897-014-9756-x
    Best OA location URL: http://doi.org/10.1007/s10897-014-9756-x
    Citation Count: 30
  • Patients’ Opinions on Genetic Counseling on the Increased Risk of Parkinson Disease among Gaucher Disease Carriers
    2017
    Summary Details
    RESTRICTED
    Title: Patients’ Opinions on Genetic Counseling on the Increased Risk of Parkinson Disease among Gaucher Disease Carriers
    Author(s): Maureen Mulhern, Louise Bier, Roy N. Alcalay, Manisha Balwani
    Journal Name: Journal of Genetic Counseling
    Publisher: Wiley
    Vol: 27
    Issue #: 3
    Start Page: 675
    End Page: 680
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s10897-017-0161-0
    Citation Count: 23
  • Sertraline for the Treatment of Depression in Alzheimer Disease: Genetic Influences
    2011
    Summary Details
    OPEN
    Title: Sertraline for the Treatment of Depression in Alzheimer Disease: Genetic Influences
    Author(s): Matthew E. Peters, Vijay Vaidya, Lea T. Drye, Paul B. Rosenberg, Barbara K. Martin, Anton P. Porsteinsson, Constantine Frangakis, Jacobo Mintzer, Daniel Weintraub, Lon S. Schneider, Peter V. Rabins, Cynthia A. Munro, Curtis L. Meinert, Constantine G. Lyketsos, Alex Dimitri
    Journal Name: Journal of Geriatric Psychiatry and Neurology
    Publisher: SAGE Publications
    Vol: 24
    Issue #: 4
    Start Page: 222
    End Page: 228
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1177/0891988711422527
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3535452
    Citation Count: 14
  • Citalopram for the Treatment of Agitation in Alzheimer Dementia
    2015
    Summary Details
    OPEN
    Title: Citalopram for the Treatment of Agitation in Alzheimer Dementia
    Author(s): Matthew E. Peters, Vijay Vaidya, Lea T. Drye, Davangere P. Devanand, Jacobo Mintzer, Bruce G. Pollock, Anton P. Porsteinsson, Paul B. Rosenberg, Lon S. Schneider, David Shade, Daniel Weintraub, Jerome A. Yesavage, Constantine G. Lyketsos, Dimitri Avramopoulos
    Journal Name: Journal of Geriatric Psychiatry and Neurology
    Publisher: SAGE Publications
    Vol: 29
    Issue #: 2
    Start Page: 59
    End Page: 64
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1177/0891988715601735
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5166612
    Citation Count: 10
  • Advanced Age, Cardiovascular Risk Burden, and Timed Up and Go Test Performance in Parkinson Disease
    2014
    Summary Details
    OPEN
    Title: Advanced Age, Cardiovascular Risk Burden, and Timed Up and Go Test Performance in Parkinson Disease
    Author(s): Vikas Kotagal, Roger L. Albin, Martijn L.T.M. Müller, R. A. Koeppe, Stephanie A. Studenski, Kirk A. Frey, N. I. Bohnen
    Journal Name: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
    Publisher: Oxford University Press (OUP)
    Vol: 69
    Issue #: 12
    Start Page: 1569
    End Page: 1575
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/gerona/glu070
    Best OA location URL: https://academic.oup.com/biomedgerontology/article-pdf/69/12/1569/9705604/glu070.pdf
    Citation Count: 15
  • β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway
    2011
    Summary Details
    OPEN
    Title: β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway
    Author(s): Qian Li, Hung‐Ming Wu, Shih‐Heng Chen, Dan Zhang, Syed F. Ali, Lynda J. Peterson, Belinda Wilson, Ru‐Band Lu, Jau‐Shyong Hong, Patrick M. Flood
    Journal Name: The Journal of Immunology
    Publisher: Oxford University Press (OUP)
    Vol: 186
    Issue #: 7
    Start Page: 4443
    End Page: 4454
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.4049/jimmunol.1002449
    Best OA location URL: https://journals.aai.org/jimmunol/article-pdf/186/7/4443/1340946/1002449.pdf
    Citation Count: 119
  • Apathy and Depression: Separate Factors in Parkinson's Disease
    2011
    Summary Details
    OPEN
    Title: Apathy and Depression: Separate Factors in Parkinson's Disease
    Author(s): Lindsey Kirsch‐Darrow, Michael Marsiske, Michael S. Okun, Russell M. Bauer, Dawn Bowers
    Journal Name: Journal of the International Neuropsychological Society
    Publisher: Cambridge University Press (CUP)
    Vol: 17
    Issue #: 6
    Start Page: 1058
    End Page: 1066
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1017/s1355617711001068
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3302577
    Citation Count: 140
  • Everyday Action Impairment in Parkinson's Disease Dementia
    2012
    Summary Details
    RESTRICTED
    Title: Everyday Action Impairment in Parkinson's Disease Dementia
    Author(s): Tania Giovannetti, Priscilla Britnell, Laura Brennan, Andrew Siderowf, Murray Grossman, David J. Libon, Brianne M. Bettcher, Francesca Rouzard, Joel Eppig, Gregory Seidel
    Journal Name: Journal of the International Neuropsychological Society
    Publisher: Cambridge University Press (CUP)
    Vol: 18
    Issue #: 5
    Start Page: 787
    End Page: 798
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1017/s135561771200046x
    Citation Count: 50
  • Are Parkinson’s Patients More Vulnerable to the Effects of Cardiovascular Risk: A Neuroimaging and Neuropsychological Study
    2017
    Summary Details
    OPEN
    Title: Are Parkinson’s Patients More Vulnerable to the Effects of Cardiovascular Risk: A Neuroimaging and Neuropsychological Study
    Author(s): Jacob D. Jones, Jared J. Tanner, Michael S. Okun, Catherine C. Price, Dawn Bowers
    Journal Name: Journal of the International Neuropsychological Society
    Publisher: Cambridge University Press (CUP)
    Vol: 23
    Issue #: 4
    Start Page: 322
    End Page: 331
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1017/s1355617717000017
    Best OA location URL: http://doi.org/10.1017/S1355617717000017
    Citation Count: 21
  • Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson’s Disease
    2017
    Summary Details
    OPEN
    Title: Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson’s Disease
    Author(s): Sarah M. Szymkowicz, Vonetta M. Dotson, Jacob D. Jones, Michael S. Okun, Dawn Bowers
    Journal Name: Journal of the International Neuropsychological Society
    Publisher: Cambridge University Press (CUP)
    Vol: 24
    Issue #: 3
    Start Page: 269
    End Page: 282
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1017/s1355617717001011
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5820218
    Citation Count: 21
  • Parkinson disease–associatedLRRK2 G2019Stransgene disrupts marrow myelopoiesis and peripheral Th17 response
    2017
    Summary Details
    OPEN
    Title: Parkinson disease–associatedLRRK2 G2019Stransgene disrupts marrow myelopoiesis and peripheral Th17 response
    Author(s): Jeongho Park, Jang-Won Lee, Scott C. Cooper, Hal E. Broxmeyer, Jason R. Cannon, Chang H. Kim
    Journal Name: Journal of Leukocyte Biology
    Publisher: Oxford University Press (OUP)
    Vol: 102
    Issue #: 4
    Start Page: 1093
    End Page: 1102
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1189/jlb.1a0417-147rr
    Best OA location URL: https://jlb.onlinelibrary.wiley.com/doi/pdfdirect/10.1189/jlb.1A0417-147RR
    Citation Count: 31
  • Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)
    2009
    Summary Details
    OPEN
    Title: Synthesis and Evaluation of a Series of Heterobiarylamides That Are Centrally Penetrant Metabotropic Glutamate Receptor 4 (mGluR4) Positive Allosteric Modulators (PAMs)
    Author(s): Darren W. Engers, Colleen M. Niswender, C. David Weaver, Satyawan Jadhav, Usha N. Menon, Rocio Zamorano, P. Jeffrey Conn, Craig W. Lindsley, Corey R. Hopkins
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 52
    Issue #: 14
    Start Page: 4115
    End Page: 4118
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm9005065
    Citation Count: 81
  • Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor Antagonists
    2010
    Summary Details
    OPEN
    Title: Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d-aspartate Receptor Antagonists
    Author(s): Cara A. Mosley, Timothy M. Acker, Kasper B. Hansen, Praseeda Mullasseril, Karen T. Andersen, Phuong Thanh Le, Kimberly Vellano, Hans Bräuner‐Osborne, Dennis C. Liotta, Stephen F. Traynelis
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 53
    Issue #: 15
    Start Page: 5476
    End Page: 5490
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm100027p
    Citation Count: 85
  • Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in Rats
    2011
    Summary Details
    OPEN
    Title: Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in Rats
    Author(s): Darren W. Engers, Julie R. Field, Uyen Le, Ya Zhou, Julie D. Bolinger, Rocio Zamorano, Anna L. Blobaum, Carrie K. Jones, Satyawan Jadhav, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 54
    Issue #: 4
    Start Page: 1106
    End Page: 1110
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm101271s
    Citation Count: 48
  • Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal Model
    2011
    Summary Details
    OPEN
    Title: Discovery, Synthesis, and Structure–Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4) with Oral Efficacy in an Antiparkinsonian Animal Model
    Author(s): Carrie K. Jones, Darren W. Engers, Analisa D. Thompson, Julie R. Field, Anna L. Blobaum, Stacey R. Lindsley, Ya Zhou, Rocco D. Gogliotti, Satyawan Jadhav, Rocio Zamorano, Jim Bogenpohl, Yoland Smith, Ryan D. Morrison, J. Scott Daniels, C. David Weaver, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Corey R. Hopkins
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 54
    Issue #: 21
    Start Page: 7639
    End Page: 7647
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm200956q
    Citation Count: 61
  • Enantiomeric Propanolamines as selectiveN-Methyl-d-aspartate 2B Receptor Antagonists
    2008
    Summary Details
    OPEN
    Title: Enantiomeric Propanolamines as selectiveN-Methyl-d-aspartate 2B Receptor Antagonists
    Author(s): Yesim A. Tahirovic, Matthew T. Geballe, Ewa Gruszecka‐Kowalik, Scott J. Myers, Polina Lyuboslavsky, Phuong Le, Adam French, Hasan A Irier, Woo‐Baeg Choi, Keith W Easterling, Hongjie Yuan, Lawrence J. Wilson, Robert J. Kotloski, James O McNamara, Raymond Dingledine, Dennis C. Liotta, Stephen F. Traynelis, James P. Snyder
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 51
    Issue #: 18
    Start Page: 5506
    End Page: 5521
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm8002153
    Citation Count: 25
  • Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents
    2014
    Summary Details
    OPEN
    Title: Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents
    Author(s): Andrew B. West, Rita M. Cowell, João Paulo Lima Daher, Mark S. Moehle, Kelly M. Hinkle, Heather L. Melrose, David G. Standaert, Laura A. Volpicelli‐Daley
    Journal Name: Journal of Comparative Neurology
    Publisher: Wiley
    Vol: 522
    Issue #: 11
    Start Page: 2465
    End Page: 2480
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/cne.23583
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4076169
    Citation Count: 139
  • 7T MRI subthalamic nucleus atlas for use with 3T MRI
    2018
    Summary Details
    OPEN
    Title: 7T MRI subthalamic nucleus atlas for use with 3T MRI
    Author(s): Mikhail Milchenko, Scott A. Norris, Kathleen L. Poston, Meghan C. Campbell, Mwiza Ushe, Joel S. Perlmutter, Abraham Z. Snyder
    Journal Name: Journal of Medical Imaging
    Publisher: SPIE-Intl Soc Optical Eng
    Vol: 5
    Issue #: 01
    Start Page: 1
    End Page: 1
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1117/1.jmi.5.1.015002
    Best OA location URL: https://www.spiedigitallibrary.org/journals/journal-of-medical-imaging/volume-5/issue-1/015002/7T-MRI-subthalamic-nucleus-atlas-for-use-with-3T-MRI/10.1117/1.JMI.5.1.015002.pdf
    Citation Count: 18
  • Structure–Activity Relationship of N,N′-Disubstituted Pyrimidinetriones as CaV1.3 Calcium Channel-Selective Antagonists for Parkinson’s Disease
    2013
    Summary Details
    OPEN
    Title: Structure–Activity Relationship of N,N′-Disubstituted Pyrimidinetriones as CaV1.3 Calcium Channel-Selective Antagonists for Parkinson’s Disease
    Author(s): Soosung Kang, Garry Cooper, Sara F. Dunne, Chi-Hao Luan, D. James Surmeier, Richard B. Silverman
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 56
    Issue #: 11
    Start Page: 4786
    End Page: 4797
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/jm4005048
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4595045
    Citation Count: 30
  • Detecting Motor Impairment in Early Parkinson’s Disease via Natural Typing Interaction With Keyboards: Validation of the neuroQWERTY Approach in an Uncontrolled At-Home Setting
    2018
    Summary Details
    OPEN
    Title: Detecting Motor Impairment in Early Parkinson’s Disease via Natural Typing Interaction With Keyboards: Validation of the neuroQWERTY Approach in an Uncontrolled At-Home Setting
    Author(s): Teresa Arroyo‐Gallego, María J. Ledesma‐Carbayo, I. Butterworth, Michele Matarazzo, Paloma Montero‐Escribano, Verónica Puertas‐Martín, Martha L. Gray, Luca Giancardo, Álvaro Sánchez‐Ferro
    Journal Name: Journal of Medical Internet Research
    Publisher: JMIR Publications Inc.
    Vol: 20
    Issue #: 3
    Start Page: e89
    End Page: e89
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.2196/jmir.9462
    Best OA location URL: https://doi.org/10.2196/jmir.9462
    Citation Count: 62
  • Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced Toxicity
    2007
    Summary Details
    OPEN
    Title: Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein-induced Toxicity
    Author(s): Sharareh Emadi, Hedieh Barkhordarian, Min S. Wang, Philip Schulz, Michael R. Sierks
    Journal Name: Journal of Molecular Biology
    Publisher: Elsevier BV
    Vol: 368
    Issue #: 4
    Start Page: 1132
    End Page: 1144
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jmb.2007.02.089
    Best OA location URL: http://doi.org/10.1016/j.jmb.2007.02.089
    Citation Count: 155
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