2201 - 2225 of 8620 Results
Title
Year
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OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29
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OPENTitle: Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 17Start Page: 4967End Page: 4970Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2009.07.072Best OA location URL: https://doi.org/10.7270/q2tb16zxCitation Count: 36
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OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Best OA location URL: https://doi.org/10.7270/q2s75grqCitation Count: 18
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulatorsJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 18Issue #: 20Start Page: 5626End Page: 5630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.08.087Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3182458Citation Count: 58
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OPENTitle: Characterization of TAE684 as a potent LRRK2 kinase inhibitorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 1864End Page: 1869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2012.01.084Best OA location URL: http://hdl.handle.net/10871/35667Citation Count: 85
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-leadJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 3Start Page: 962End Page: 966Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.11.104Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3787871Citation Count: 55
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OPENTitle: Role of Elongation and Secondary Pathways in S6 Amyloid Fibril GrowthJournal Name: Biophysical JournalPublisher: Elsevier BVVol: 102Issue #: 9Start Page: 2167End Page: 2175Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.bpj.2012.03.047Best OA location URL: http://www.cell.com/article/S0006349512003888/pdfCitation Count: 36
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OPENTitle: Discovery and characterization of a novel series of N -phenylsulfonyl-1 H -pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu 4 )Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4955388Citation Count: 5
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OPENTitle: Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutationsJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 35Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20150128Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/35/5/e00254/477473/bsr035e254.pdfCitation Count: 27
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OPENTitle: Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 2Issue #: 28Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3000664Best OA location URL: http://doi.org/10.1126/scitranslmed.3000664Citation Count: 135
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OPENTitle: Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 4Issue #: 141Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3003985Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3462009Citation Count: 490
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OPENTitle: Identifying blood-brain-barrier selective single-chain antibody fragmentsJournal Name: Biotechnology JournalPublisher: WileyVol: 9Issue #: 5Start Page: 664End Page: 674Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/biot.201300550Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4073886Citation Count: 23
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OPENTitle: Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGEJournal Name: BMC BioinformaticsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2105-7-475Best OA location URL: https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-475Citation Count: 38
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OPENTitle: Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samplesJournal Name: Biotechnology ProgressPublisher: WileyVol: 29Issue #: 2Start Page: 463End Page: 471Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/btpr.1698Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3618510Citation Count: 24
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OPENTitle: Cost effectiveness of preventing falls and improving mobility in people with Parkinson disease: protocol for an economic evaluation alongside a clinical trialJournal Name: BMC GeriatricsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2318-8-23Best OA location URL: https://bmcgeriatr.biomedcentral.com/track/pdf/10.1186/1471-2318-8-23Citation Count: 31
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OPENTitle: Stratification of candidate genes for Parkinson’s disease using weighted protein-protein interaction network analysisJournal Name: BMC GenomicsPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1186/s12864-018-4804-9Best OA location URL: https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/s12864-018-4804-9.pdfCitation Count: 42
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OPENTitle: Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairmentJournal Name: BMC NeurologyPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1186/s12883-015-0403-4Best OA location URL: https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/s12883-015-0403-4Citation Count: 51
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OPENTitle: Analysis of number needed to treat for droxidopa in patients with symptomatic neurogenic orthostatic hypotensionJournal Name: BMC NeurologyPublisher: Springer Science and Business Media LLCVol: 16Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12883-016-0665-5Best OA location URL: https://bmcneurol.biomedcentral.com/track/pdf/10.1186/s12883-016-0665-5Citation Count: 4
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OPENTitle: Evaluation of rotigotine transdermal patch for the treatment of apathy and motor symptoms in Parkinson’s diseaseJournal Name: BMC NeurologyPublisher: Springer Science and Business Media LLCVol: 16Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1186/s12883-016-0610-7Best OA location URL: https://bmcneurol.biomedcentral.com/track/pdf/10.1186/s12883-016-0610-7Citation Count: 55
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OPENTitle: Exercise improves cognition in Parkinson's disease: The PRET-PD randomized, clinical trialJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 12Start Page: 1657End Page: 1663Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26291Best OA location URL: http://doi.org/10.1002/mds.26291Citation Count: 168
- Failure of Sequential Pallidal and Motor Thalamus DBS for Rapid‐Onset Dystonia‐Parkinsonism (DYT12)2017OPENTitle: Failure of Sequential Pallidal and Motor Thalamus DBS for Rapid‐Onset Dystonia‐Parkinsonism (DYT12)Journal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 5Issue #: 4Start Page: 444End Page: 445Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12559Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12559Citation Count: 11
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OPENTitle: Clinimetric testing of the comprehensive cervical dystonia rating scaleJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 4Start Page: 563End Page: 569Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26534Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4833533Citation Count: 46
- Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings2016OPENTitle: Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy FindingsJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 2Start Page: 250End Page: 256Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26476Best OA location URL: https://europepmc.org/articles/pmc4747813?pdf=renderCitation Count: 77
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OPENTitle: Clinical and demographic characteristics related to onset site and spread of cervical dystoniaJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 12Start Page: 1874End Page: 1882Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26817Best OA location URL: http://doi.org/10.1002/mds.26817Citation Count: 43
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OPENTitle: Intake of antioxidant vitamins and risk of Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 12Start Page: 1909End Page: 1914Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26819Best OA location URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41263027Citation Count: 102