MJFF Publications

Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway

2024

OPEN

Title: Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway

Author(s): Nicholas Sweeney, Tae Yeon Kim, Cody Morrison, Liangping Li, Diana Acosta, Jiawen Liang, Nithin V. Datla, Julie Fitzgerald, Hen‐Wei Huang, Xianglan Liu, Gregory Huang Tan, Min Wu, Kate Karelina, Chelsea E. Bray, Zachary M. Weil, Douglas W. Scharre, Geidy E. Serrano, Takashi Saito, Takaomi C. Saido, Thomas G. Beach, Olga N. Kokiko‐Cochran, Jonathan P. Godbout, Gail V.W. Johnson, Hongjun Fu

Journal Name: Acta Neuropathologica

Publisher: Springer Science and Business Media LLC

Vol: 148

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-10-11

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1007/s00401-024-02810-1

Best OA location URL:

Citation Count: 0

High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson’s disease

2024

OPEN

Title: High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson’s disease

Author(s): Darian Williams, Logan M. Glasstetter, Tiffany T. Jong, Tiffany Chen, Abhijeet Kapoor, Sha Zhu, Yanping Zhu, Raul Calvo, Alexandra Gehrlein, Kimberly Wong, Andrew N. Hogan, David J. Vocadlo, Ravi Jagasia, Juan Marugán, Ellen Sidransky, Mark J. Henderson, Yu Chen

Journal Name: Proceedings of the National Academy of Sciences

Publisher: Proceedings of the National Academy of Sciences

Vol: 121

Issue #: 42

Start Page:

End Page:

Publication Date: 2024-10-10

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1073/pnas.2406009121

Best OA location URL:

Citation Count: 0

Single-cell somatic copy number variants in brain using different amplification methods and reference genomes

2024

OPEN

Title: Single-cell somatic copy number variants in brain using different amplification methods and reference genomes

Author(s): Ester Kalef-Ezra, Zeliha Gözde Turan, Diego Pérez‐Rodríguez, Ida Bomann, Sairam Behera, Caoimhe Morley, Sonja W. Scholz, Zane Jaunmuktane, Jonas Demeulemeester, Fritz J. Sedlazeck, Christos Proukakis

Journal Name: Communications Biology

Publisher: Springer Science and Business Media LLC

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-10-09

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s42003-024-06940-w

Best OA location URL:

Citation Count: 0

α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease

2024

OPEN

Title: α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease

Author(s): Fanni F. Geibl, Martin T. Henrich, Zhong Xie, Enrico Zampese, Jun Ueda, Tatiana Tkatch, David L. Wokosin, Elena Nasiri, Constantin A. Grotmann, Valina L. Dawson, Ted M. Dawson, Navdeep S. Chandel, Wolfgang H. Oertel, D. James Surmeier

Journal Name: Molecular Neurodegeneration

Publisher: Springer Science and Business Media LLC

Vol: 19

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-10-08

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s13024-024-00756-2

Best OA location URL:

Citation Count: 0

POLCAM: instant molecular orientation microscopy for the life sciences

2024

OPEN

Title: POLCAM: instant molecular orientation microscopy for the life sciences

Author(s): Ezra Bruggeman, Oumeng Zhang, Lisa-Maria Needham, Markus Körbel, Sam Daly, Matthew R. Cheetham, Ruby Peters, Tingting Wu, Andrey S. Klymchenko, Simon J. Davis, Ewa K. Paluch, David Klenerman, Matthew D. Lew, Kevin O’Holleran, Steven F. Lee

Journal Name: Nature Methods

Publisher: Springer Science and Business Media LLC

Vol: 21

Issue #: 10

Start Page:

End Page:

Publication Date: 2024-10-07

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41592-024-02382-8

Best OA location URL:

Citation Count: 0

Brain-first forms of Parkinson's disease are over-represented in patients with non-responsive resting tremor

2024

OPEN

Title: Brain-first forms of Parkinson's disease are over-represented in patients with non-responsive resting tremor

Author(s): Marcelo Mendonça, Pedro Antônio Muniz Ferreira, Raquel Barbosa, Joaquim Alves da Silva

Journal Name: Neurobiology of Disease

Publisher: Elsevier BV

Vol: 201

Issue #:

Start Page: 106691

End Page: 106691

Publication Date: 2024-10-01

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1016/j.nbd.2024.106691

Best OA location URL:

Citation Count: 0

ScRNAbox: empowering single-cell RNA sequencing on high performance computing systems

2024

OPEN

Title: ScRNAbox: empowering single-cell RNA sequencing on high performance computing systems

Author(s): Rhalena A. Thomas, Michael R. Fiorini, Saeid Amiri, Edward A. Fon, Sali M. K. Farhan

Journal Name: BMC Bioinformatics

Publisher: Springer Science and Business Media LLC

Vol: 25

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-10-01

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s12859-024-05935-y

Best OA location URL:

Citation Count: 0

SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson’s disease

2024

OPEN

Title: SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson’s disease

Author(s): Polina Petkova‐Kirova, Anastasia Kolchina, Stephan Baas, Gudrun Wagenpfeil, Marcus M. Unger, Julia M. Schulze‐Hentrich, Rita Bernhardt

Journal Name: Frontiers in Pharmacology

Publisher: Frontiers Media SA

Vol: 15

Issue #:

Start Page:

End Page:

Publication Date: 2024-09-30

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fphar.2024.1477009

Best OA location URL:

Citation Count: 0

Surface‐Based Morphometry Analysis of the Cerebral Cortex in Patients With Probable Idiopathic Rapid Eye Movement Sleep Behavior Disorder

2024

OPEN

Title: Surface‐Based Morphometry Analysis of the Cerebral Cortex in Patients With Probable Idiopathic Rapid Eye Movement Sleep Behavior Disorder

Author(s): Milad Najafzadeh, Athareh Saeeidian‐Mehr, Hossein Akbari‐Lalimi, Zohre Ganji, Shahrokh Nasseri, Hoda Zare, Luigi Ferini‐Strambi

Journal Name: Brain and Behavior

Publisher: Wiley

Vol: 14

Issue #: 10

Start Page:

End Page:

Publication Date: 2024-09-30

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1002/brb3.70057

Best OA location URL:

Citation Count: 0

RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes

2024

OPEN

Title: RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes

Author(s): Xingjian Li, Hanwen Zhu, Bo Huang, Xianting Li, Hee‐Soo Kim, Haiyan Tan, Yuanxi Zhang, Insup Choi, Junmin Peng, Pingyi Xu, Ji Sun, Zhenyu Yue

Journal Name: Nature Communications

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-29

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41467-024-52723-6

Best OA location URL:

Citation Count: 0

Graphene Microelectrode Arrays, 4D Structured Illumination Microscopy, and a Machine Learning Spike Sorting Algorithm Permit the Analysis of Ultrastructural Neuronal Changes During Neuronal Signaling in a Model of Niemann–Pick Disease Type C

2024

OPEN

Title: Graphene Microelectrode Arrays, 4D Structured Illumination Microscopy, and a Machine Learning Spike Sorting Algorithm Permit the Analysis of Ultrastructural Neuronal Changes During Neuronal Signaling in a Model of Niemann–Pick Disease Type C

Author(s): Meng Lü, Ernestine Hui, Marius Brockhoff, Jakob Träuble, Ana Fernández‐Villegas, Oliver J. Burton, Jacob R. Lamb, Edward Ward, Philippa J. Woodhams, Wadood Tadbier, Nino F. Läubli, Stephan Hofmann, Clemens F. Kaminski, Antonio Lombardo, Gabriele S. Kaminski Schierle

Journal Name: Advanced Science

Publisher: Wiley

Vol: 11

Issue #: 44

Start Page:

End Page:

Publication Date: 2024-09-28

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1002/advs.202402967

Best OA location URL:

Citation Count: 0

APOE contributes to longitudinal impulse control disorders progression in Parkinson’s disease

2024

OPEN

Title: APOE contributes to longitudinal impulse control disorders progression in Parkinson’s disease

Author(s): Linxi Chen, Xinwei He, Lingqun Mao, Peng Liu

Journal Name: BMC Psychiatry

Publisher: Springer Science and Business Media LLC

Vol: 24

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-27

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1186/s12888-024-06084-5

Best OA location URL:

Citation Count: 0

Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

2024

OPEN

Title: Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

Author(s): Valerie Joers, Benjamin Murray, Caroline McLaughlin, Danielle Oliver, Hannah E Staley, Jazmyn Coronado, Cindy Achat‐Mendes, Sanam Golshani, Sean D. Kelly, Matthew Goodson, Danica Lee, Fredric P. Manfredsson, Bob Moore, Malú G. Tansey

Journal Name: Journal of Neuroinflammation

Publisher: Springer Science and Business Media LLC

Vol: 21

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-27

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1186/s12974-024-03221-5

Best OA location URL:

Citation Count: 0

Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts

2024

OPEN

Title: Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts

Author(s): Tien Dam, Gennaro Pagano, Michael C. Brumm, Caroline Gochanour, Kathleen L. Poston, Daniel Weintraub, Lana M. Chahine, Christopher S. Coffey, Caroline M. Tanner, Catherine Kopil, Yuge Xiao, Sohini Chowdhury, Luis Concha‐Marambio, Peter DiBiaso, Tatiana Foroud, Mark Frasier, Danna Jennings, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Thomas J. Montine, Kelly Nudelman, John Seibyl, Todd Sherer, Andrew Singleton, Diane Stephenson, Matthew Stern, Claudio Soto, Eduardo Tolosa, Andrew Siderowf, Billy Dunn, Tanya Simuni, John Seibyl

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-27

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00789-w

Best OA location URL:

Citation Count: 0

VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1

2024

OPEN

Title: VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1

Author(s): Berrak Uğur, Florian Schueder, Jimann Shin, Michael G. Hanna, Yumei Wu, Marianna Leonzino, Maohan Su, Anthony R. McAdow, Catherine Wilson, John H. Postlethwait, Lilianna Solnica‐Krezel, Joerg Bewersdorf, Pietro De Camilli

Journal Name: Journal of Cell Biology

Publisher: Rockefeller University Press

Vol: 223

Issue #: 12

Start Page:

End Page:

Publication Date: 2024-09-27

Open Access(OA) Status: OPEN

License: cc-by, cc-by, cc-by

DOI - Digital Object Identifier: 10.1083/jcb.202311189

Best OA location URL:

Citation Count: 0

Topography of Cholinergic Nerve Terminal Vulnerability and Balance Self-Efficacy in Parkinson's Disease

2024

OPEN

Title: Topography of Cholinergic Nerve Terminal Vulnerability and Balance Self-Efficacy in Parkinson's Disease

Author(s): Jaimie Barr, Robert Vangel, Prabesh Kanel, Stiven Roytman, Chatkaew Pongmala, Roger L. Albin, Peter J. H. Scott, Nicolaas I. Bohnen

Journal Name: Journal of Integrative Neuroscience

Publisher: IMR Press

Vol: 23

Issue #: 9

Start Page:

End Page:

Publication Date: 2024-09-24

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.31083/j.jin2309178

Best OA location URL:

Citation Count: 0

CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PET

2024

OPEN

Title: CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PET

Author(s): Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Tanner Y. Jacobson, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul S. Aisen, Reisa A. Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Otero Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth C. Mormino, Rachel F. Buckley, Keith A. Johnson, Hyun‐Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin‐Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. López, David A. Bennett, Muhammad Ali, Tammie L.S. Benzinger, Carlos Cruchaga, Diana A. Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, Andrew J. Saykin

Journal Name: Nature Communications

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-20

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41467-024-52298-2

Best OA location URL:

Citation Count: 0

Activation of parkin by a molecular glue

2024

OPEN

Title: Activation of parkin by a molecular glue

Author(s): Véronique Sauvé, Eric Stefan, Nathalie Croteau, Thomas Goiran, Rayan Fakih, Nupur Bansal, Adelajda Zorba, Jing Fang, Paramasivam Murugan, Shimin Chen, Edward A. Fon, Warren D. Hirst, Laura Silvian, Jean‐François Trempe, Kalle Gehring

Journal Name: Nature Communications

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-19

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41467-024-51889-3

Best OA location URL:

Citation Count: 0

Advancing Parkinson’s Disease Research in Canada: The Canadian Open Parkinson Network (C-OPN) Cohort

2024

OPEN

Title: Advancing Parkinson’s Disease Research in Canada: The Canadian Open Parkinson Network (C-OPN) Cohort

Author(s): Marisa Cressatti, Gabriel David Pinilla-Monsalve, Mathieu Blais, Catherine P. Normandeau, Clotilde Degroot, Iris Kathol, Sarah Bogard, Anna Bendas, Richard Camicioli, Nicolas Dupré, Ziv Gan‐Or, David A. Grimes, Lorraine V. Kalia, Penny A. MacDonald, Martin J. McKeown, Davide Martino, Janis M. Miyasaki, Michael G. Schlossmacher, A. Jon Stoessl, Antonio P. Strafella, Edward A. Fon, Oury Monchi

Journal Name: Journal of Parkinson's Disease

Publisher: SAGE Publications

Vol: 14

Issue #: 7

Start Page: 1

End Page: 14

Publication Date: 2024-09-19

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.3233/jpd-240213

Best OA location URL:

Citation Count: 0

An interpretable deep learning framework identifies proteomic drivers of Alzheimer’s disease

2024

OPEN

Title: An interpretable deep learning framework identifies proteomic drivers of Alzheimer’s disease

Author(s): Elena Panizza, Richard A. Cerione

Journal Name: Frontiers in Cell and Developmental Biology

Publisher: Frontiers Media SA

Vol: 12

Issue #:

Start Page:

End Page:

Publication Date: 2024-09-17

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fcell.2024.1379984

Best OA location URL:

Citation Count: 0

Head-up Tilt Sleeping to Treat Orthostatic Intolerance in a Patient with Advanced Parkinson’s Disease: A Case Report

2024

OPEN

Title: Head-up Tilt Sleeping to Treat Orthostatic Intolerance in a Patient with Advanced Parkinson’s Disease: A Case Report

Author(s): A. H. Stam, Sharon Shmuely, Nienke M. de Vries, Roland D. Thijs, Mirjam van Kesteren-Biegstraaten, Bastiaan R. Bloem

Journal Name: Case Reports in Neurology

Publisher: S. Karger AG

Vol: 16

Issue #: 1

Start Page: 256

End Page: 261

Publication Date: 2024-09-17

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1159/000541424

Best OA location URL:

Citation Count: 0

How storage post sampling influences the stability of sebum when used for mass spectrometry metabolomics analysis?

2024

OPEN

Title: How storage post sampling influences the stability of sebum when used for mass spectrometry metabolomics analysis?

Author(s): Caitlin Walton-Doyle, Eleanor Sinclair, Hosne Ara Begum, Katherine A. Hollywood, Drupad K. Trivedi, Perdita E. Barran

Journal Name: Scientific Reports

Publisher: Springer Science and Business Media LLC

Vol: 14

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-17

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41598-024-71598-7

Best OA location URL:

Citation Count: 0

NeuroBooster Array: A Genome‐Wide Genotyping Platform to Study Neurological Disorders Across Diverse Populations

2024

OPEN

Title: NeuroBooster Array: A Genome‐Wide Genotyping Platform to Study Neurological Disorders Across Diverse Populations

Author(s): Sara Bandrés‐Ciga, Faraz Faghri, Elisa Majounie, Mathew J. Koretsky, Jonggeol Jeffrey Kim, Kristin Levine, Hampton L. Leonard, Mary B. Makarious, Hirotaka Iwaki, Peter Wild Crea, Dena Hernández, Henk W. Berendse, Kimberley Billingsley, Katja Lohmann, Christine Klein, Steven Lubbe, Edwin Jabbari, Paula Saffie Awad, Derek P. Narendra, Armando Reyes‐Palomares, John P. Quinn, Claudia Schulte, Huw R. Morris, Bryan J. Traynor, Sonja W. Scholz, Henry Houlden, John Hardy, Sonya B. Dumanis, Ekemini Riley, Cornelis Blauwendraat, Andrew Singleton, Mike A. Nalls, Janina M. Jeff, Dan Vitale

Journal Name: Movement Disorders

Publisher: Wiley

Vol: 39

Issue #: 11

Start Page:

End Page:

Publication Date: 2024-09-16

Open Access(OA) Status: OPEN

License: cc-by-nc-nd, cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/mds.29902

Best OA location URL:

Citation Count: 0

A Novel MAG Variant Causes Hereditary Spastic Paraplegia in a Consanguineous Pakistani Family

2024

OPEN

Title: A Novel MAG Variant Causes Hereditary Spastic Paraplegia in a Consanguineous Pakistani Family

Author(s): Rabia Akram, Haseeb Anwar, Humaira Muzaffar, Valentina Turchetti, Tracy Lau, Barbara Vona, Ehtisham Ul Haq Makhdoom, Javed Iqbal, Shahid Mahmood Baig, Ghulam Hussain, Stéphanie Efthymiou, Henry Houlden

Journal Name: Genes

Publisher: MDPI AG

Vol: 15

Issue #: 9

Start Page: 1203

End Page: 1203

Publication Date: 2024-09-13

Open Access(OA) Status: OPEN

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.3390/genes15091203

Best OA location URL:

Citation Count: 0

Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W

2024

OPEN

Title: Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W

Author(s): Bernardo A. Bustillos, Liam T. Cocker, Matt Coban, Caleb A. Weber, Jenny M. Bredenberg, Paige K Boneski, Joanna Siuda, Jarosław Sławek, Andreas Puschmann, Derek P. Narendra, Caroline Graff, Zbigniew K. Wszołek, Melissa E. Murray, Owen A. Ross, Thomas R. Caulfield, Wolfdieter Springer, Fabienne C. Fiesel

Journal Name: Cells

Publisher: MDPI AG

Vol: 13

Issue #: 18

Start Page: 1540

End Page: 1540

Publication Date: 2024-09-13

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3390/cells13181540

Best OA location URL:

Citation Count: 0

RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer’s disease

2024

OPEN

Title: RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer’s disease

Author(s): Genís Campoy‐Campos, Júlia Solana‐Balaguer, Anna Guisado-Corcoll, Almudena Chicote‐González, Pol Garcia‐Segura, Leticia Pérez‐Sisqués, Adrian Gabriel Torres, Mercè Canal, Laura Molina‐Porcel, Enrique Santamaría, Enrique Santamaría, Lluı́s Ribas de Pouplana, Albert Giralt, Eulàlia Martı́, Albert Giralt, Esther Pérez‐Navarro, Cristina Malagelada

Journal Name: Nucleic Acids Research

Publisher: Oxford University Press (OUP)

Vol: 52

Issue #: 18

Start Page:

End Page:

Publication Date: 2024-09-12

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1093/nar/gkae776

Best OA location URL:

Citation Count: 0

Understanding what aspects of Parkinson’s disease matter most to patients and families

2024

OPEN

Title: Understanding what aspects of Parkinson’s disease matter most to patients and families

Author(s): Jennifer R. Mammen, Mirinda Brown Tyo, Joyce Cadorette, Jamie Adams, Yuge Xiao, Diane Stephenson, C. Bale

Journal Name: Scientific Reports

Publisher: Springer Science and Business Media LLC

Vol: 14

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-09-11

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41598-024-71555-4

Best OA location URL:

Citation Count: 0

Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer

2024

OPEN

Title: Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer

Author(s): Elena Buglakova, Måns Ekelöf, Michaela Schwaiger-Haber, Lisa Schlicker, Martijn R. Molenaar, Mohammed Shahraz, Lachlan Stuart, Andreas Eisenbarth, Volker Hilsenstein, Gary J. Patti, Almut Schulze, Marteinn T. Snaebjornsson, Theodore Alexandrov

Journal Name: Nature Metabolism

Publisher: Springer Science and Business Media LLC

Vol: 6

Issue #: 9

Start Page:

End Page:

Publication Date: 2024-09-09

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s42255-024-01118-4

Best OA location URL:

Citation Count: 0

SVA Regulation of Transposable Element Clustered Transcription within the Major Histocompatibility Complex Genomic Class II Region of the Parkinson’s Progression Markers Initiative

2024

OPEN

Title: SVA Regulation of Transposable Element Clustered Transcription within the Major Histocompatibility Complex Genomic Class II Region of the Parkinson’s Progression Markers Initiative

Author(s): Jerzy K. Kulski, Abigail L. Pfaff, Sulev Kõks

Journal Name: Genes

Publisher: MDPI AG

Vol: 15

Issue #: 9

Start Page: 1185

End Page: 1185

Publication Date: 2024-09-09

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3390/genes15091185

Best OA location URL:

Citation Count: 0

A novel super-resolution microscopy platform for cutaneous alpha-synuclein detection in Parkinson’s disease

2024

OPEN

Title: A novel super-resolution microscopy platform for cutaneous alpha-synuclein detection in Parkinson’s disease

Author(s): Ofir Sade, Daphna Fischel, Noa Barak-Broner, Shir Halevi, Irit Gottfried, Dana Bar-On, Stefan Sachs, Anat Mirelman, Avner Thaler, Aviv Gour, Meir Kestenbaum, Mali Gana Weisz, Saar Anis, Claudio Soto, Melanie Shanie Roitman, Shimon Shahar, Kathrin Doppler, Markus Sauer, Alessio Di Fonzo, Nirit Lev, Roy N. Alcalay, Sharon Hassin‐Baer, Uri Ashery

Journal Name: Frontiers in Molecular Neuroscience

Publisher: Frontiers Media SA

Vol: 17

Issue #:

Start Page:

End Page:

Publication Date: 2024-09-04

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fnmol.2024.1431549

Best OA location URL:

Citation Count: 0

Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials

2024

OPEN

Title: Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials

Author(s): Chadwick W. Christine, Peggy Auinger, E. Forti, Lyvin Tat, Noemi Cannizzaro, Andres Yamil Regalado Mustafa, Jay M. Iyer, David Oakes, Ralph Green

Journal Name: Journal of Parkinson's Disease

Publisher: SAGE Publications

Vol: 14

Issue #: 6

Start Page: 1243

End Page: 1255

Publication Date: 2024-09-03

Open Access(OA) Status: OPEN

License: cc-by-nc

DOI - Digital Object Identifier: 10.3233/jpd-240035

Best OA location URL:

Citation Count: 0

Cohort-specific Boolean models highlight different regulatory modules during Parkinson’s disease progression

2024

OPEN

Title: Cohort-specific Boolean models highlight different regulatory modules during Parkinson’s disease progression

Author(s): Ahmed Abdelmonem Hemedan, Venkata Satagopam, Reinhard Schneider, Marek Ostaszewski

Journal Name: iScience

Publisher: Elsevier BV

Vol: 27

Issue #: 10

Start Page: 110956

End Page: 110956

Publication Date: 2024-09-01

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1016/j.isci.2024.110956

Best OA location URL:

Citation Count: 0

Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models

2024

OPEN

Title: Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models

Author(s): Erin M. McConnell, Dennis Chan, Katelyn Ventura, Joshua P. Callahan, Kathryn P. Harris, Vernon Hunt, Spencer Boisjoli, Daniel Knight, Emma Monk, Matthew R. Holahan, Maria C. DeRosa

Journal Name: Molecular Therapy - Nucleic Acids

Publisher: Elsevier BV

Vol: 35

Issue #: 3

Start Page: 102251

End Page: 102251

Publication Date: 2024-09-01

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1016/j.omtn.2024.102251

Best OA location URL:

Citation Count: 1

SynBot is an open-source image analysis software for automated quantification of synapses

2024

OPEN

Title: SynBot is an open-source image analysis software for automated quantification of synapses

Author(s): Christabel Xin Tan, J.J. Ramirez, W. Christopher Risher, Yizhi Wang, Dolores Irala, Çağla Eroğlu

Journal Name: Cell Reports Methods

Publisher: Elsevier BV

Vol: 4

Issue #: 9

Start Page: 100861

End Page: 100861

Publication Date: 2024-09-01

Open Access(OA) Status: OPEN

License: cc-by, cc-by, cc-by

DOI - Digital Object Identifier: 10.1016/j.crmeth.2024.100861

Best OA location URL:

Citation Count: 0

Validating New Symptom Emergence as a Patient-Centric Outcome Measure for PD Clinical Trials

2024

RESTRICTED

Title: Validating New Symptom Emergence as a Patient-Centric Outcome Measure for PD Clinical Trials

Author(s): Haotian Zou, Glenn T. Stebbins, Tanya Simuni, Sheng Luo, Jesse M. Cedarbaum

Journal Name: Parkinsonism & Related Disorders

Publisher: Elsevier BV

Vol: 128

Issue #:

Start Page: 107118

End Page: 107118

Publication Date: 2024-09-01

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1016/j.parkreldis.2024.107118

Best OA location URL:

Citation Count: 0

An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes

2024

OPEN

Title: An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes

Author(s): Axel Gandy, Gilles Maussion, S. Al-Habyan, Michaël Nicouleau, Zhipeng You, Carol X.‐Q. Chen, Narges Abdian, Nathalia Aprahamian, Andrea I. Krahn, Louise Larocque, Thomas M. Durcan, Éric Deneault

Journal Name: International Journal of Molecular Sciences

Publisher: MDPI AG

Vol: 25

Issue #: 17

Start Page: 9493

End Page: 9493

Publication Date: 2024-08-31

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3390/ijms25179493

Best OA location URL:

Citation Count: 0

Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations

2024

OPEN

Title: Bridging the gap: Multi‐omics profiling of brain tissue in Alzheimer's disease and older controls in multi‐ethnic populations

Author(s): Joseph S. Reddy, Laura Heath, Abby Vander Linden, Mariet Allen, Kátia de Paiva Lopes, Fatemeh Seifar, Erming Wang, Yiyi Ma, William L. Poehlman, Zachary Quicksall, Alexi Runnels, Yanling Wang, Duc M. Duong, Luming Yin, Kaiming Xu, Erica Modeste, Anantharaman Shantaraman, Eric B. Dammer, Lingyan Ping, Stephanie R. Oatman, Jo Scanlan, Charlotte C.G. Ho, Minerva M. Carrasquillo, Merve Atık, Geovanna Yepez, Adriana O. Mitchell, Thuy Nguyen, Xianfeng Chen, David X. Márquez, Hasini Reddy, Harrison Xiao, Sudha Seshadri, Richard Mayeux, Stefan Prokop, Edward B. Lee, Geidy E. Serrano, Thomas G. Beach, Andrew F. Teich, V. Haroutunian, Edward J. Fox, Marla Gearing, Aliza P. Wingo, Thomas S. Wingo, James J. Lah, Allan I. Levey, Dennis W. Dickson, Lisa L. Barnes, Philip L. De Jager, Bin Zhang, David A. Bennett, Nicholas T. Seyfried, Anna K. Greenwood, Nilüfer Ertekin‐Taner

Journal Name: Alzheimer's & Dementia

Publisher: Wiley

Vol:

Issue #:

Start Page:

End Page:

Publication Date: 2024-08-30

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/alz.14208

Best OA location URL:

Citation Count: 1

Inflammation and heterogeneity in synucleinopathies

2024

RESTRICTED

Title: Inflammation and heterogeneity in synucleinopathies

Author(s): Antoine Freuchet, Anaëlle Pinçon, A Sette, Cecilia S. Lindestam Arlehamn

Journal Name: Frontiers in Immunology

Publisher: Frontiers Media SA

Vol: 15

Issue #:

Start Page:

End Page:

Publication Date: 2024-08-30

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.3389/fimmu.2024.1432342

Best OA location URL:

Citation Count: 0

Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson’s disease

2024

OPEN

Title: Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson’s disease

Author(s): Qianling Lu, Zhuang Zhu, Heng Zhang, Caiting Gan, Aidi Shan, Mengxi Gao, Huimin Sun, Xingyue Cao, Yongsheng Yuan, Joseph B. Tracy, Qirui Zhang, Kezhong Zhang

Journal Name: Translational Psychiatry

Publisher: Springer Science and Business Media LLC

Vol: 14

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-08-30

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1038/s41398-024-03070-z

Best OA location URL:

Citation Count: 0

Medication improves velocity, reaction time, and movement time but not amplitude or error during memory‐guided reaching in Parkinson's disease

2024

OPEN

Title: Medication improves velocity, reaction time, and movement time but not amplitude or error during memory‐guided reaching in Parkinson's disease

Author(s): Michael P. Trevarrow, Miranda J. Munoz, Yessenia M. Rivera, Rishabh Arora, Quentin H. Drane, Gian Pal, Leonard Verhagen Metman, Lisa C. Goelz, Daniel M. Corcos, Fabian J. David

Journal Name: Physiological Reports

Publisher: Wiley

Vol: 12

Issue #: 17

Start Page:

End Page:

Publication Date: 2024-08-29

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.14814/phy2.16150

Best OA location URL:

Citation Count: 0

Sensorimotor functioning changes in response to global exercise versus handwriting upper limb exercise training in Parkinson’s disease, results from a phase II randomised controlled trial

2024

OPEN

Title: Sensorimotor functioning changes in response to global exercise versus handwriting upper limb exercise training in Parkinson’s disease, results from a phase II randomised controlled trial

Author(s): Íbis Ariana Peña de Moraes, Johnny Collett, Talita Dias da Silva, Marloes Franssen, Surabhi Mitta, Paweł Zalewski, Andy Meaney, Derick T Wade, Hooshang Izadi, Charlotte Winward, Carlos Bandeira de Mello Monteiro, Helen Dawes

Journal Name: PLOS ONE

Publisher: Public Library of Science (PLoS)

Vol: 19

Issue #: 8

Start Page: e0309217

End Page: e0309217

Publication Date: 2024-08-29

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1371/journal.pone.0309217

Best OA location URL:

Citation Count: 0

Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils

2024

OPEN

Title: Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils

Author(s): Derrick Lau, Yuan Tang, Vijaya B. Kenche, Thomas Copie, Daryan Kempe, Eve Jary, Noah J. Graves, Maté Biro, Colin L. Masters, Nicolas Dzamko, Yann Gambin, Emma Sierecki

Journal Name: ACS Chemical Neuroscience

Publisher: American Chemical Society (ACS)

Vol: 15

Issue #: 18

Start Page:

End Page:

Publication Date: 2024-08-28

Open Access(OA) Status: OPEN

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1021/acschemneuro.4c00185

Best OA location URL:

Citation Count: 0

Synthesis at the Interface of Chemistry and Biology

2024

RESTRICTED

Title: Synthesis at the Interface of Chemistry and Biology

Author(s): Peter G. Schultz

Journal Name: Accounts of Chemical Research

Publisher: American Chemical Society (ACS)

Vol: 57

Issue #: 18

Start Page:

End Page:

Publication Date: 2024-08-28

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1021/acs.accounts.4c00320

Best OA location URL:

Citation Count: 0

Diffusion tensor metrics, motor and non-motor symptoms in de novo Parkinson’s disease

2024

RESTRICTED

Title: Diffusion tensor metrics, motor and non-motor symptoms in de novo Parkinson’s disease

Author(s): Nayron Medeiros Soares, Pedro Henrique Rodrigues da Silva, Gabriela Magalhães Pereira, Renata Ferranti Leoni, Carlos Roberto de Mello Rieder, Thatiane Alves Pianoschi Alva

Journal Name: Neuroradiology

Publisher: Springer Science and Business Media LLC

Vol: 66

Issue #: 11

Start Page:

End Page:

Publication Date: 2024-08-27

Open Access(OA) Status: RESTRICTED

License:

DOI - Digital Object Identifier: 10.1007/s00234-024-03452-6

Best OA location URL:

Citation Count: 1

Acceptability of digital health technologies in early Parkinson's disease: lessons from WATCH-PD

2024

OPEN

Title: Acceptability of digital health technologies in early Parkinson's disease: lessons from WATCH-PD

Author(s): Tairmae Kangarloo, Robert D. Latzman, John Adams, Rebecca J. Dorsey, Melissa Kostrzebski, Joan Severson, David G. Anderson, Fay B. Horak, Diane Stephenson, Joshua D. Cosman

Journal Name: Frontiers in Digital Health

Publisher: Frontiers Media SA

Vol: 6

Issue #:

Start Page:

End Page:

Publication Date: 2024-08-26

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.3389/fdgth.2024.1435693

Best OA location URL:

Citation Count: 0

Dynamic balance and gait impairments in Parkinson’s disease: novel cholinergic patterns

2024

OPEN

Title: Dynamic balance and gait impairments in Parkinson’s disease: novel cholinergic patterns

Author(s): Nicolaas I. Bohnen, Uroš Marušič, Stiven Roytman, Rebecca Paalanen, F. Michalakis, Theodore R. Brown, Peter J. H. Scott, Giulia Carli, Roger L. Albin, Prabesh Kanel

Journal Name: Brain Communications

Publisher: Oxford University Press (OUP)

Vol: 6

Issue #: 5

Start Page:

End Page:

Publication Date: 2024-08-26

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1093/braincomms/fcae286

Best OA location URL:

Citation Count: 0

Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation

2024

OPEN

Title: Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation

Author(s): Árpád Dobolyi, Melinda Cservenák, Attila G. Bagó, Chun Chen, Анна Степанова, Krisztina Paál, Jeonghyoun Lee, Miklós Palkovits, Gavin Hudson, Christos Chinopoulos

Journal Name: Communications Biology

Publisher: Springer Science and Business Media LLC

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-08-24

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1038/s42003-024-06751-z

Best OA location URL:

Citation Count: 0

Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits

2024

OPEN

Title: Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits

Author(s): Alexandros C. Kokotos, Aldana M. Antoniazzi, Santiago R. Unda, Myung S. Ko, Daehun Park, David Eliezer, Michael G. Kaplitt, Pietro De Camilli, Timothy A. Ryan

Journal Name: Science Advances

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 10

Issue #: 34

Start Page:

End Page:

Publication Date: 2024-08-23

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/sciadv.adn6016

Best OA location URL:

Citation Count: 0

Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies

2024

OPEN

Title: Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies

Author(s): Paras S. Minhas, Jeffrey R. Jones, Amira Latif‐Hernandez, Yuki Sugiura, Aarooran S. Durairaj, Qian Wang, Siddhita D. Mhatre, Takeshi Uenaka, Joshua Crapser, Travis E. Conley, Hannah E. Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C. Jenkins, Yeonglong Albert Ay, Matthew Matrongolo, Ryan Goodman, Traci Fang Newmeyer, Kelly J. Heard, Austin Kang, Edward N. Wilson, Tao Yang, Erik M. Ullian, Geidy E. Serrano, Thomas G. Beach, Marius Wernig, Joshua D. Rabinowitz, Makoto Suematsu, Frank M. Longo, Melanie R. McReynolds, Fred H. Gage, Katrin I. Andreasson

Journal Name: Science

Publisher: American Association for the Advancement of Science (AAAS)

Vol: 385

Issue #: 6711

Start Page:

End Page:

Publication Date: 2024-08-23

Open Access(OA) Status: OPEN

License:

DOI - Digital Object Identifier: 10.1126/science.abm6131

Best OA location URL: https://doi.org/10.1101/2024.06.23.598940

Citation Count: 1

Exploring Analysis Approaches for Using the Dopamine Transporter Striatal Binding Ratio in Early‐ to Mid‐Stage Parkinson's Disease Modification Trials

2024

OPEN

Title: Exploring Analysis Approaches for Using the Dopamine Transporter Striatal Binding Ratio in Early‐ to Mid‐Stage Parkinson's Disease Modification Trials

Author(s): Nirosen Vijiaratnam, Christine Girges, Dilan Athauda, Alexa King, Grace Auld, Rachel McComish, Kashfia Chowdhury, Simon S. Skene, Kate Maclagan, К. Ray Chaudhuri, Vincenzo Libri, John Dickson, Thomas Foltynie

Journal Name: Movement Disorders Clinical Practice

Publisher: Wiley

Vol: 11

Issue #: 11

Start Page:

End Page:

Publication Date: 2024-08-22

Open Access(OA) Status: OPEN

License: cc-by

DOI - Digital Object Identifier: 10.1002/mdc3.14191

Best OA location URL:

Citation Count: 0

Animations

MJFF Publications