5251 - 5300 of 7939 Results
Title
Year
-
RESTRICTEDTitle: Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?Journal Name: European Journal of NeurosciencePublisher: WileyVol: 49Issue #: 4Start Page: 453End Page: 462Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1111/ejn.14314Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ejn.14314Citation Count: 15
-
RESTRICTEDTitle: Abstract #81: Improving Neurostimulation Clinical Trial Design with Patient Experience DataJournal Name: Brain StimulationPublisher: Elsevier BVVol: 12Issue #: 2Start Page: e28End Page: e29Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.brs.2018.12.088Citation Count: 0
-
RESTRICTEDTitle: Targeting the Dopaminergic System in AutoimmunityJournal Name: Journal of Neuroimmune PharmacologyPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page: 57End Page: 73Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s11481-019-09834-5Citation Count: 53
-
OPENTitle: miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signalingJournal Name: Cell Death & DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 2Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41419-018-1295-1Best OA location URL: https://www.nature.com/articles/s41419-018-1295-1.pdfCitation Count: 64
-
RESTRICTEDTitle: Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRsJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 148Issue #:Start Page: 220End Page: 228Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2019.01.015Citation Count: 13
-
RESTRICTEDTitle: Risk of Parkinson's disease dementia related to level I MDS PD‐MCIJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 3Start Page: 430End Page: 435Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27617Citation Count: 40
-
OPENTitle: Conversion of Quinazoline Modulators from Inhibitors to Activators of β-GlucocerebrosidaseJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 62Issue #: 3Start Page: 1218End Page: 1230Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acs.jmedchem.8b01294Best OA location URL: https://europepmc.org/articles/pmc6467782?pdf=renderCitation Count: 21
-
OPENTitle: Evaluation of the detection of GBA missense mutations and other variants using the Oxford Nanopore MinIONJournal Name: Molecular Genetics & Genomic MedicinePublisher: WileyVol: 7Issue #: 3Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mgg3.564Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mgg3.564Citation Count: 71
-
OPENTitle: Identifying the neural correlates of doorway freezing in Parkinson's diseaseJournal Name: Human Brain MappingPublisher: WileyVol: 40Issue #: 7Start Page: 2055End Page: 2064Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/hbm.24506Best OA location URL: https://europepmc.org/articles/pmc6865388?pdf=renderCitation Count: 43
-
OPENTitle: Crystal structure of the WD40 domain dimer of LRRK2Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 116Issue #: 5Start Page: 1579End Page: 1584Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1073/pnas.1817889116Best OA location URL: https://www.pnas.org/content/pnas/116/5/1579.full.pdfCitation Count: 73
-
OPENTitle: Longitudinal Connectomes as a Candidate Progression Marker for Prodromal Parkinson’s DiseaseJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 12Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2018.00967Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2018.00967/pdfCitation Count: 21
-
OPENTitle: Multimodal dopaminergic and free-water imaging in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 62Issue #:Start Page: 10End Page: 15Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.01.007Best OA location URL: http://manuscript.elsevier.com/S1353802019300070/pdf/S1353802019300070.pdfCitation Count: 47
-
RESTRICTEDTitle: Reduced gray matter volume in cognitively preserved COMT 158Val/Val Parkinson’s disease patients and its association with cognitive declineJournal Name: Brain Imaging and BehaviorPublisher: Springer Science and Business Media LLCVol: 14Issue #: 2Start Page: 321End Page: 328Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s11682-018-0022-yCitation Count: 13
-
RESTRICTEDTitle: Measuring the Impact of Patient Engagement and Patient Centricity in Clinical Research and DevelopmentJournal Name:Publisher:Vol:Issue #:Start Page: 216847901881751End Page: 216847901881751Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1177/2168479018817517;Citation Count: 21
-
RESTRICTEDTitle: Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and PathologyJournal Name: International Journal of Molecular SciencesPublisher: MDPI AGVol: 20Issue #: 1Start Page: 141End Page: 141Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.3390/ijms20010141Best OA location URL: https://www.mdpi.com/1422-0067/20/1/141/pdf?version=1546425034Citation Count: 55
-
RESTRICTEDTitle: Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gasJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 129Issue #: 1Start Page: 34End Page: 45Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1172/jci120848Best OA location URL: http://www.jci.org/articles/view/120848/files/pdfCitation Count: 114
- Smell status in functional movement disorders: New clues for diagnosis and underlying mechanisms2019OPENTitle: Smell status in functional movement disorders: New clues for diagnosis and underlying mechanismsJournal Name: Clinical Neurology and NeurosurgeryPublisher: Elsevier BVVol: 177Issue #:Start Page: 68End Page: 72Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.clineuro.2018.12.017Best OA location URL: http://repositorio.udes.edu.co/bitstreams/ad61c2c5-4b3f-43cf-9122-973e12714ede/downloadCitation Count: 4
- Abstract2019OPENTitle: AbstractJournal Name: Brain and Neuroscience AdvancesPublisher: SAGE PublicationsVol: 3Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1177/2398212819855490Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/2398212819855490Citation Count: 3
-
RESTRICTED
-
OPENTitle: Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE‐ε4/TOMM40 long poly‐T repeat allele variantsJournal Name: Alzheimer's & Dementia: Translational Research & Clinical InterventionsPublisher: WileyVol: 5Issue #: 1Start Page: 814End Page: 824Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.trci.2019.08.005Best OA location URL: https://doi.org/10.1016/j.trci.2019.08.005Citation Count: 16
-
OPENTitle: Anodal tDCS modulates cortical activity and synchronization in Parkinson's disease depending on motor processingJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 22Issue #:Start Page: 101689End Page: 101689Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101689Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101689Citation Count: 19
-
OPENTitle: Assessment of a prognostic MRI biomarker in early de novo Parkinson's diseaseJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 24Issue #:Start Page: 101986End Page: 101986Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101986Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101986Citation Count: 35
-
RESTRICTEDTitle: Atrophy in midbrain & cerebral/cerebellar pedunculi is characteristic for progressive supranuclear palsy – A double-validation whole-brain meta-analysisJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 22Issue #:Start Page: 101722End Page: 101722Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101722Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101722Citation Count: 23
-
OPENTitle: Bayesian Longitudinal Modeling of Early Stage Parkinson’s Disease Using DaTscan ImagesJournal Name: Lecture Notes in Computer SciencePublisher: Springer International PublishingVol:Issue #:Start Page: 405End Page: 416Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/978-3-030-20351-1_31Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258684Citation Count: 5
-
RESTRICTEDTitle: BIOLOGICAL AND COGNITIVE MARKERS OF PRESENILIN1 E280A AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE: A COMPREHENSIVE REVIEW OF THE COLOMBIAN KINDREDJournal Name: The Journal Of Prevention of Alzheimer's DiseasePublisher: SERDIVol:Issue #:Start Page: 1End Page: 9Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.14283/jpad.2019.6Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925534Citation Count: 37
-
OPENTitle: Cerebellar resting-state functional connectivity in Parkinson's disease and multiple system atrophy: Characterization of abnormalities and potential for differential diagnosis at the single-patient levelJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 22Issue #:Start Page: 101720End Page: 101720Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101720Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101720Citation Count: 40
-
OPENTitle: Cognitive processes that indirectly affect olfactory dysfunction in Parkinson's diseaseJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 1Issue #:Start Page: 13End Page: 20Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.prdoa.2019.07.003Best OA location URL: https://doi.org/10.1016/j.prdoa.2019.07.003Citation Count: 4
-
OPENTitle: Complementary motivational roles of nigroaccumbens and nigrostriatal dopaminergic pathwaysJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 1Start Page: 45End Page: 45Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27504Best OA location URL: http://deepblue.lib.umich.edu/bitstream/2027.42/147822/1/mds27504_am.pdfCitation Count: 3
-
OPENTitle: Effect of Single-Nucleotide Polymorphisms on Decline of Dopamine Transporter Availability in Parkinson's DiseaseJournal Name: Journal of Clinical NeurologyPublisher: Korean Neurological AssociationVol: 15Issue #: 1Start Page: 102End Page: 102Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3988/jcn.2019.15.1.102Best OA location URL: http://www.thejcn.com/Synapse/Data/PDFData/0145JCN/jcn-15-102.pdfCitation Count: 5
-
RESTRICTEDTitle: FDG-PET hypometabolism is more sensitive than MRI atrophy in Parkinson's disease: A whole-brain multimodal imaging meta-analysisJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 21Issue #:Start Page: 101594End Page: 101594Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2018.11.004Best OA location URL: https://doi.org/10.1016/j.nicl.2018.11.004Citation Count: 53
-
OPENTitle: Free-water imaging of the hippocampus is a sensitive marker of Alzheimer's diseaseJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 24Issue #:Start Page: 101985End Page: 101985Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101985Best OA location URL: http://adni.loni.usc.edu/wp-content/uploads/how_to_apply/ADNI_Acknowledgement_List.pdfCitation Count: 45
-
OPENTitle: Frizzled-7-targeted delivery of zinc oxide nanoparticles to drug-resistant breast cancer cellsJournal Name: NanoscalePublisher: Royal Society of Chemistry (RSC)Vol: 11Issue #: 27Start Page: 12858End Page: 12870Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1039/c9nr01277jBest OA location URL: http://hdl.handle.net/10044/1/70762Citation Count: 48
-
OPENTitle: Hippocampal CA1 subfield predicts episodic memory impairment in Parkinson's diseaseJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 23Issue #:Start Page: 101824End Page: 101824Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101824Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101824Citation Count: 50
-
RESTRICTEDTitle: Huntington disease: A quarter century of progress since the gene discoveryJournal Name: Journal of the Neurological SciencesPublisher: Elsevier BVVol: 396Issue #:Start Page: 52End Page: 68Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.jns.2018.09.022Citation Count: 59
-
OPENTitle: Joint pattern analysis applied to PET DAT and VMAT2 imaging reveals new insights into Parkinson's disease induced presynaptic alterationsJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 23Issue #:Start Page: 101856End Page: 101856Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101856Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101856Citation Count: 22
-
OPENTitle: Neurophysics Assessment of the Muscle Bioenergy Generated by Transcranial Magnetic StimulationJournal Name: ResearchPublisher: American Association for the Advancement of Science (AAAS)Vol: 2019Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.34133/2019/7109535Best OA location URL: https://doi.org/10.34133/2019/7109535Citation Count: 6
- Nutritional ketosis for mild cognitive impairment in Parkinson's disease: A controlled pilot trial2019OPENTitle: Nutritional ketosis for mild cognitive impairment in Parkinson's disease: A controlled pilot trialJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 1Issue #:Start Page: 41End Page: 47Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.prdoa.2019.07.006Best OA location URL: https://doi.org/10.1016/j.prdoa.2019.07.006Citation Count: 41
- Prediction of cognitive progression in Parkinson's disease using three cognitive screening measures2019OPENTitle: Prediction of cognitive progression in Parkinson's disease using three cognitive screening measuresJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 1Issue #:Start Page: 91End Page: 97Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.prdoa.2019.08.006Best OA location URL: https://doi.org/10.1016/j.prdoa.2019.08.006Citation Count: 28
-
OPENTitle: Quantification of blood–brain barrier transport and neuronal toxicity of unlabelled multiwalled carbon nanotubes as a function of surface chargeJournal Name: NanoscalePublisher: Royal Society of Chemistry (RSC)Vol: 11Issue #: 45Start Page: 22054End Page: 22069Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1039/c9nr02866hBest OA location URL: http://hdl.handle.net/10044/1/74557Citation Count: 36
-
RESTRICTEDTitle: Targeting the proteostasis network in Huntington’s diseaseJournal Name: Ageing Research ReviewsPublisher: Elsevier BVVol: 49Issue #:Start Page: 92End Page: 103Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.arr.2018.11.006Best OA location URL: https://doi.org/10.1016/j.arr.2018.11.006Citation Count: 63
-
OPENTitle: The experience of off periods: Qualitative analysis of interviews with persons with Parkinson's and carepartnersJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 1Issue #:Start Page: 31End Page: 36Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.prdoa.2019.07.008Best OA location URL: https://doi.org/10.1016/j.prdoa.2019.07.008Citation Count: 7
-
OPENTitle: To be or not to be pink(1): contradictory findings in an animal model for Parkinson’s diseaseJournal Name: Brain CommunicationsPublisher: Oxford University Press (OUP)Vol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/braincomms/fcz016Best OA location URL: https://academic.oup.com/braincomms/article-pdf/1/1/fcz016/33639299/fcz016.pdfCitation Count: 30
-
RESTRICTEDTitle: LRRK2‐mediated Rab10 phosphorylation in immune cells from Parkinson's disease patientsJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 3Start Page: 406End Page: 415Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27601Citation Count: 90
-
OPENTitle: Reproducible detection of nigral iron deposition in 2 Parkinson's disease cohortsJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 3Start Page: 416End Page: 419Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27608Best OA location URL: https://europepmc.org/articles/pmc6608731?pdf=renderCitation Count: 35
-
OPENTitle: Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein DestabilizationJournal Name: Molecular NeurobiologyPublisher: Springer Science and Business Media LLCVol: 56Issue #: 8Start Page: 5273End Page: 5286Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s12035-018-1449-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s12035-018-1449-2.pdfCitation Count: 15
-
OPENTitle: Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S MutationJournal Name: Stem Cell ReportsPublisher: Elsevier BVVol: 12Issue #: 1Start Page: 29End Page: 41Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.stemcr.2018.11.021Best OA location URL: http://www.cell.com/article/S2213671118304909/pdfCitation Count: 66
- Ultra–Low-Dose18F-Florbetaben Amyloid PET Imaging Using Deep Learning with Multi-Contrast MRI Inputs2018OPENTitle: Ultra–Low-Dose18F-Florbetaben Amyloid PET Imaging Using Deep Learning with Multi-Contrast MRI InputsJournal Name: RadiologyPublisher: Radiological Society of North America (RSNA)Vol: 290Issue #: 3Start Page: 649End Page: 656Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1148/radiol.2018180940Best OA location URL: https://europepmc.org/articles/pmc6394782?pdf=renderCitation Count: 197
-
OPENTitle: Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodiesJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-018-35729-1Best OA location URL: https://www.nature.com/articles/s41598-018-35729-1.pdfCitation Count: 24
-
OPENTitle: Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activityJournal Name: RNA BiologyPublisher: Informa UK LimitedVol: 16Issue #: 1Start Page: 93End Page: 103Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/15476286.2018.1559689Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15476286.2018.1559689?needAccess=trueCitation Count: 7
- Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease2018OPENTitle: Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer diseaseJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 137Issue #: 4Start Page: 585End Page: 598Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-018-1947-3Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-018-1947-3.pdfCitation Count: 103