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MJFF Publications

5351 - 5400 of 7939 Results
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  • OPEN
    Title: Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aah4066
    Citation Count: 623
  • OPEN
    Title: Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease
    Journal Name: Metabolites
    Publisher: MDPI AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/metabo8040071
    Citation Count: 42
  • OPEN
    Title: The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.644
    Citation Count: 394
  • OPEN
    Title: The vermiform appendix impacts the risk of developing Parkinson’s disease
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aar5280
    Citation Count: 232
  • OPEN
    Title: δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer’s disease
    Journal Name: Molecular Psychiatry
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41380-018-0286-z
    Citation Count: 61
  • OPEN
    Title: A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181471
    Citation Count: 49
  • OPEN
    Title: Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation
    Journal Name: Glia
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/glia.23482
    Citation Count: 46
  • OPEN
    Title: The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2018.00326
    Citation Count: 77
  • OPEN
    Title: Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-018-1337-8
    Citation Count: 35
  • OPEN
    Title: The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson’s disease
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-34490-9
    Citation Count: 119
  • RESTRICTED
    Title: PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27523
    Best OA location URL:
    Citation Count: 42
  • OPEN
    Title: The transition between turning and sitting in patients with Parkinson's disease: A wearable device detects an unexpected sequence of events
    Journal Name: Gait & Posture
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.gaitpost.2018.10.018
    Citation Count: 29
  • OPEN
    Title: Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jalz.2018.08.012
    Citation Count: 233
  • OPEN
    Title: Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddy365
    Citation Count: 59
  • OPEN
    Title: Mechanisms underlying prelimbic prefrontal cortex mGlu3/mGlu5-dependent plasticity and reversal learning deficits following acute stress
    Journal Name: Neuropharmacology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neuropharm.2018.10.013
    Citation Count: 49
  • OPEN
    Title: Reduced glucocerebrosidase activity in monocytes from patients with Parkinson’s disease
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-33921-x
    Citation Count: 89
  • OPEN
    Title: Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain
    Journal Name: Stem Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.stemcr.2018.09.004
    Citation Count: 42
  • OPEN
    Title: Validation of a performance‐based assessment of cognitive functional ability in Parkinson's disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27487
    Citation Count: 18
  • OPEN
    Title: Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-018-05892-0
    Citation Count: 343
  • OPEN
    Title: Modulatory Effects of Levodopa on Cerebellar Connectivity in Parkinson’s Disease
    Journal Name: The Cerebellum
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s12311-018-0981-y
    Citation Count: 17
  • OPEN
    Title: Progressive Decline in Gray and White Matter Integrity in de novo Parkinson’s Disease: An Analysis of Longitudinal Parkinson Progression Markers Initiative Diffusion Tensor Imaging Data
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2018.00318
    Citation Count: 64
  • OPEN
    Title: Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2
    Journal Name: Neurochemical Research
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s11064-018-2650-4
    Citation Count: 8
  • RESTRICTED
    Title: 123I‐FP‐CIT SPECT [(123) I‐2β‐carbomethoxy‐3β‐(4‐iodophenyl)‐N‐(3‐fluoropropyl) nortropane single photon emission computed tomography] Imaging in a p.A53T α‐synuclein Parkinson's disease cohort versus Parkinson's disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27451
    Best OA location URL:
    Citation Count: 9
  • OPEN
    Title: Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-018-0282-4
    Citation Count: 185
  • OPEN
    Title: Naftazone in advanced Parkinson's disease: An acute L-DOPA challenge randomized controlled trial
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.10.005
    Citation Count: 16
  • OPEN
    Title: Abstracts from the 50th European Society of Human Genetics Conference: Posters
    Journal Name: European Journal of Human Genetics
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41431-018-0247-7
    Citation Count: 4
  • OPEN
    Title: Dopamine-related dissociation of cortical and subcortical brain activations in cognitively unimpaired Parkinson’s disease patients OFF and ON medications
    Journal Name: Neuropsychologia
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.neuropsychologia.2018.07.024
    Citation Count: 15
  • OPEN
    Title: Importance of low diagnostic Accuracy for early Parkinson's disease
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27485
    Citation Count: 84
  • RESTRICTED
    Title: Meta-analysis of amantadine efficacy for improving preclinical research reliability
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27486
    Best OA location URL:
    Citation Count: 7
  • RESTRICTED
    Title: Modeling Parkinson’s disease and treatment complications in rodents: Potentials and pitfalls of the current options
    Journal Name: Behavioural Brain Research
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.bbr.2017.12.014
    Best OA location URL:
    Citation Count: 20
  • RESTRICTED
    Title: Sleep disorders and Parkinson disease; lessons from genetics
    Journal Name: Sleep Medicine Reviews
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.smrv.2018.01.006
    Citation Count: 33
  • OPEN
    Title: The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress
    Journal Name: Redox Biology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.redox.2018.07.021
    Citation Count: 74
  • RESTRICTED
    Title: The Linked Clinical Trials initiative (LCT) for Parkinson's disease
    Journal Name: European Journal of Neuroscience
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1111/ejn.14175
    Best OA location URL:
    Citation Count: 18
  • RESTRICTED
    Title: Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches
    Journal Name: Bioconjugate Chemistry
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acs.bioconjchem.8b00548
    Citation Count: 24
  • OPEN
    Title: Modulation of intracellular calcium signaling by microRNA-34a-5p
    Journal Name: Cell Death & Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41419-018-1050-7
    Citation Count: 28
  • OPEN
    Title: Regional vesicular acetylcholine transporter distribution in human brain: A [18F]fluoroethoxybenzovesamicol positron emission tomography study
    Journal Name: Journal of Comparative Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/cne.24541
    Citation Count: 48
  • RESTRICTED
    Title: 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2018.09.018
    Best OA location URL:
    Citation Count: 31
  • RESTRICTED
    Title: Animal models of neurodegenerative diseases
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0236-8
    Citation Count: 374
  • OPEN
    Title: CSF Aβ1–42 level is associated with cognitive decline in early Parkinson’s disease with rapid eye movement sleep behavior disorder
    Journal Name: Translational Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40035-018-0129-5
    Citation Count: 11
  • OPEN
    Title: USP 14 inhibition corrects an in vivo model of impaired mitophagy
    Journal Name: EMBO Molecular Medicine
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.15252/emmm.201809014
    Citation Count: 82
  • OPEN
    Title: Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181434
    Citation Count: 21
  • OPEN
    Title: Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-018-0066-0
    Citation Count: 48
  • OPEN
    Title: Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study
    Journal Name: Acta Neurologica Scandinavica
    Publisher: Hindawi Limited
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ane.13028
    Citation Count: 36
  • OPEN
    Title: Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease
    Journal Name: PROTEOMICS
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/pmic.201800108
    Citation Count: 57
  • OPEN
    Title: Unraveling connectivity changes due to dopaminergic therapy in chronically treated Parkinson’s disease patients
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-31988-0
    Citation Count: 21
  • OPEN
    Title: Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders
    Journal Name: JAMA
    Publisher: American Medical Association (AMA)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/jama.2018.12917
    Citation Count: 324
  • OPEN
    Title: β2‐adrenoreceptor medications and risk of Parkinson disease
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.25341
    Citation Count: 65
  • OPEN
    Title: Insights into the Influence of Specific Splicing Events on the Structural Organization of LRRK2
    Journal Name: International Journal of Molecular Sciences
    Publisher: MDPI AG
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/ijms19092784
    Citation Count: 2
  • OPEN
    Title: Common and rare GCH1 variants are associated with Parkinson's disease
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2018.09.008
    Citation Count: 28
  • RESTRICTED
    Title: An mGlu4‐Positive Allosteric Modulator Alleviates Parkinsonism in Primates
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27462
    Best OA location URL:
    Citation Count: 48
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