5501 - 5550 of 8715 Results
Title
Year
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OPENTitle: Association of women-specific health factors in the severity of Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 9Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-023-00524-xBest OA location URL: https://www.nature.com/articles/s41531-023-00524-x.pdfCitation Count: 8
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OPENTitle: Video-based Parkinson’s disease assessments in a nationwide cohort of Fox Insight participantsJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 4Issue #:Start Page: 100094End Page: 100094Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.prdoa.2021.100094Best OA location URL: https://doi.org/10.1016/j.prdoa.2021.100094Citation Count: 28
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OPENTitle: Dystrophin-associated protein scaffolding in brain requires α-dystrobrevinJournal Name: NeuroReportPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 21Issue #: 10Start Page: 695End Page: 699Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/wnr.0b013e32833b0a3bBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2889226Citation Count: 14
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OPENTitle: Machine Learning-Based Prediction of Impulse Control Disorders in Parkinson’s Disease From Clinical and Genetic DataJournal Name: IEEE Open Journal of Engineering in Medicine and BiologyPublisher: Institute of Electrical and Electronics Engineers (IEEE)Vol: 3Issue #:Start Page: 96End Page: 107Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1109/ojemb.2022.3178295Best OA location URL: https://ieeexplore.ieee.org/ielx7/8782705/8937520/09783181.pdfCitation Count: 10
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OPENTitle: Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophilsJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 475Issue #: 1Start Page: 23End Page: 44Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bcj20170803Best OA location URL: https://portlandpress.com/biochemj/article-pdf/475/1/23/694098/bcj-2017-0803.pdfCitation Count: 164
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OPENTitle: LRRK2 p.M1646T is associated with glucocerebrosidase activity and with Parkinson's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 103Issue #:Start Page: 142.e1End Page: 142.e5Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2021.02.018Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8178224Citation Count: 22
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RESTRICTEDTitle: Microstructural patterns in substantia nigra subregions are associated with depression and olfactory impairments in Parkinson’s diseaseJournal Name: Clinical Neurology and NeurosurgeryPublisher: Elsevier BVVol: 251Issue #:Start Page: 108817End Page: 108817Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.clineuro.2025.108817Citation Count: 1
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OPENTitle: Detecting and monitoring the symptoms of Parkinson's disease using smartphones: A pilot studyJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 21Issue #: 6Start Page: 650End Page: 653Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.02.026Citation Count: 351
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RESTRICTEDTitle: A data-driven system to identify REM sleep behavior disorder and to predict its progression from the prodromal stage in Parkinson's diseaseJournal Name: Sleep MedicinePublisher: Elsevier BVVol: 77Issue #:Start Page: 238End Page: 248Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.sleep.2020.04.010Citation Count: 46
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OPENTitle: Hsp110 mitigates α-synuclein pathology in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 116Issue #: 48Start Page: 24310End Page: 24316Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1903268116Best OA location URL: https://www.pnas.org/content/pnas/116/48/24310.full.pdfCitation Count: 53
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OPENTitle: Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrinaJournal Name: Journal of Extracellular BiologyPublisher: WileyVol: 1Issue #: 10Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/jex2.59Best OA location URL: https://doi.org/10.1002/jex2.59Citation Count: 104
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OPENTitle: Activation and Purification of ß‐Glucocerebrosidase by Exploiting its Transporter LIMP‐2 – Implications for Novel Treatment Strategies in Gaucher's and Parkinson's DiseaseJournal Name: Advanced SciencePublisher: WileyVol: 11Issue #: 25Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/advs.202401641Best OA location URL: https://doi.org/10.1002/advs.202401641Citation Count: 3
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OPENTitle: Cryo-TEM structure of β-glucocerebrosidase in complex with its transporter LIMP-2Journal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 16Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-025-58340-1Best OA location URL: https://doi.org/10.1038/s41467-025-58340-1Citation Count: 1
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RESTRICTEDTitle: A novel brain penetrant c-Abl tyrosine kinase inhibitor: Paving a path forward to success in disease modification in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 108Issue #:Start Page: 105325End Page: 105325Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2023.105325Citation Count: 0
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OPENTitle: A Novel α‐Synuclein K58N Missense Variant in a Patient with Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.70030Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.70030Citation Count: 0
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RESTRICTEDTitle: Effect of tricyclic antidepressants on L-DOPA-induced dyskinesia and motor improvement in hemi-parkinsonian ratsJournal Name: Pharmacology Biochemistry and BehaviorPublisher: Elsevier BVVol: 142Issue #:Start Page: 64End Page: 71Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.pbb.2016.01.004Citation Count: 22
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RESTRICTEDTitle: Local Regulation of Striatal Dopamine Release Shifts from Predominantly Cholinergic in Mice to GABAergic in MacaquesJournal Name: The Journal of NeurosciencePublisher: Society for NeuroscienceVol: 45Issue #: 11Start Page: e1692242025End Page: e1692242025Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.1523/jneurosci.1692-24.2025Best OA location URL: https://escholarship.org/uc/item/4p96822fCitation Count: 0
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OPENTitle: Investigation of Somatic Mutations in Human Brains Targeting Genes Associated With Parkinson's DiseaseJournal Name: Frontiers in NeurologyPublisher: Frontiers Media SAVol: 11Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fneur.2020.570424Best OA location URL: https://www.frontiersin.org/articles/10.3389/fneur.2020.570424/pdfCitation Count: 9
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RESTRICTEDTitle: Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2AJournal Name: European Journal of Nuclear Medicine and Molecular ImagingPublisher: Springer Science and Business Media LLCVol: 48Issue #: 5Start Page: 1327End Page: 1338Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s00259-020-05149-3Citation Count: 46
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RESTRICTEDTitle: Reply to: “Use of Robust Norming to Create a Sensitive Cognitive Summary Score in De Novo Parkinson's Disease: An Illustrative Example”Journal Name: Movement DisordersPublisher: WileyVol: 40Issue #: 7Start Page: 1444End Page: 1445Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.30247Citation Count: 0
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OPENTitle: Preclinical modeling of chronic inhibition of the Parkinson’s disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivoJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 16Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-021-00441-8Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-021-00441-8Citation Count: 46
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RESTRICTEDTitle: Brain and gut: Partners in crimeJournal Name: Movement DisordersPublisher: WileyVol: 33Issue #: 7Start Page: 1098End Page: 1098Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27407Citation Count: 1
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OPENTitle: Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activityJournal Name: RNA BiologyPublisher: Informa UK LimitedVol: 16Issue #: 1Start Page: 93End Page: 103Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/15476286.2018.1559689Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15476286.2018.1559689?needAccess=trueCitation Count: 7
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OPENTitle: Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic DemandJournal Name: Cell MetabolismPublisher: Elsevier BVVol: 27Issue #: 2Start Page: 439End Page: 449.e5Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.cmet.2017.12.008Best OA location URL: http://www.cell.com/article/S1550413117307210/pdfCitation Count: 534
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OPENTitle: Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controlsJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 89Issue #: 19Start Page: 1959End Page: 1969Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1212/wnl.0000000000004609Best OA location URL: https://n.neurology.org/content/neurology/89/19/1959.full.pdfCitation Count: 145
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OPENTitle: Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic SignalingJournal Name: Molecular CellPublisher: Elsevier BVVol: 77Issue #: 5Start Page: 1124End Page: 1142.e10Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.molcel.2019.11.013Best OA location URL: https://doi.org/10.1016/j.molcel.2019.11.013Citation Count: 197
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RESTRICTEDTitle: Reaction-Based “Off–On” Fluorescent Probe Enabling Detection of Endogenous Labile Fe2+ and Imaging of Zn2+-induced Fe2+ Flux in Living Cells and Elevated Fe2+ in Ischemic StrokeJournal Name: Bioconjugate ChemistryPublisher: American Chemical Society (ACS)Vol: 27Issue #: 2Start Page: 302End Page: 308Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/acs.bioconjchem.5b00259Citation Count: 68
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OPENTitle: A new biology of cell penetrating peptidesJournal Name: Peptide SciencePublisher: WileyVol: 113Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/pep2.24154Best OA location URL: http://hdl.handle.net/2436/623251Citation Count: 7
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OPENTitle: PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity terminationJournal Name: Journal of Cell BiologyPublisher: Rockefeller University PressVol: 217Issue #: 6Start Page: 2167End Page: 2184Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-saDOI - Digital Object Identifier: 10.1083/jcb.201708053Best OA location URL: https://rupress.org/jcb/article-pdf/217/6/2167/1067112/jcb_201708053.pdfCitation Count: 49
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OPENTitle: The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s diseaseJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-017-0456-2Best OA location URL: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-017-0456-2Citation Count: 87
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OPENTitle: A blood-based marker of mitochondrial DNA damage in Parkinson’s diseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 15Issue #: 711Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.abo1557Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/11135133Citation Count: 53
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RESTRICTEDTitle: Reply to letter to the editor “Adaptive DBS in Parkinson's disease: Headlines, perspectives and challenges”Journal Name: Brain StimulationPublisher: Elsevier BVVol: 12Issue #: 5Start Page: 1330End Page: 1331Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.brs.2019.06.014Citation Count: 0
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OPENTitle: N-type Ca2+ channels mediate the stimuli-dependent α-synuclein secretion in mouse striatumJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/s41531-025-01110-zBest OA location URL: https://www.nature.com/articles/s41531-025-01110-z.pdfCitation Count: 0
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OPENTitle: Parkinson's Disease Biomarkers: Resources for Discovery and ValidationJournal Name: NeuropsychopharmacologyPublisher: Springer Science and Business Media LLCVol: 39Issue #: 1Start Page: 241End Page: 242Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/npp.2013.246Best OA location URL: https://www.nature.com/articles/npp2013246.pdfCitation Count: 6
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OPENTitle: Associating white matter microstructural integrity and improvements in reactive stepping in people with Parkinson’s DiseaseJournal Name: Brain Imaging and BehaviorPublisher: Springer Science and Business Media LLCVol: 18Issue #: 4Start Page: 852End Page: 862Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11682-024-00867-wBest OA location URL: https://www.researchsquare.com/article/rs-3117246/latest.pdfCitation Count: 1
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OPENTitle: The Cooperative Health Research in South Tyrol (CHRIS) study: rationale, objectives, and preliminary resultsJournal Name: Journal of Translational MedicinePublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12967-015-0704-9Best OA location URL: https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-015-0704-9Citation Count: 89
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OPENTitle: Toward the quantification of α-synuclein aggregates with digital seed amplification assaysJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 121Issue #: 3Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1073/pnas.2312031121Best OA location URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10801878/pdf/pnas.202312031.pdfCitation Count: 14
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OPENTitle: Money without collaboration won't bring curesJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 19Issue #: 2Start Page: 127End Page: 127Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nm0213-127Best OA location URL: https://www.nature.com/articles/nm0213-127.pdfCitation Count: 4
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OPENTitle: Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacyJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 12Start Page: 2915End Page: 2919Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.04.041Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4899947Citation Count: 3
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OPENTitle: Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F-4 for Tau Protein: A First-in-Human PET StudyJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 16Issue #: 6Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1021/acschemneuro.4c00866Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/11926865Citation Count: 0
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RESTRICTEDTitle: Challenges of Parkinson's disease GWASs in African peopleJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 22Issue #: 11Start Page: 975End Page: 976Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/s1474-4422(23)00361-7Citation Count: 1
- Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism2022OPENTitle: Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonismJournal Name: Pharmacological ResearchPublisher: Elsevier BVVol: 182Issue #:Start Page: 106338End Page: 106338Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.phrs.2022.106338Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9733952Citation Count: 12
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OPENTitle: Mitochondrial genomic variation in dementia with Lewy bodies: association with disease risk and neuropathological measuresJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-022-01399-4Best OA location URL: https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-022-01399-4Citation Count: 1
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OPENTitle: Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonistsJournal Name: British Journal of PharmacologyPublisher: WileyVol: 175Issue #: 5Start Page: 782End Page: 796Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/bph.14123Best OA location URL: https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bph.14123Citation Count: 20
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OPENTitle: Assessing Visuospatial Skills in Parkinson's: Comparison of Neuropsychological Assessment Battery Visual Discrimination to the Judgment of Line OrientationJournal Name: Archives of Clinical NeuropsychologyPublisher: Oxford University Press (OUP)Vol: 32Issue #: 1Start Page: 123End Page: 127Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/arclin/acw102Best OA location URL: https://academic.oup.com/acn/article-pdf/32/1/123/9951631/acw102.pdfCitation Count: 4
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OPENTitle: Dopamine genetic risk score predicts impulse control behaviors in Parkinson’s diseaseJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 5Issue #:Start Page: 100113End Page: 100113Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.prdoa.2021.100113Best OA location URL: https://doi.org/10.1016/j.prdoa.2021.100113Citation Count: 12
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OPENTitle: Interaction of Mitochondrial Polygenic Score and Lifestyle Factors in LRRK2 p.Gly2019Ser ParkinsonismJournal Name: Movement DisordersPublisher: WileyVol: 38Issue #: 10Start Page: 1837End Page: 1849Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/mds.29563Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29563Citation Count: 15
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OPENTitle: Mitochondrial DNA deletions in the cerebrospinal fluid of patients with idiopathic REM sleep behaviour disorderJournal Name: eBioMedicinePublisher: Elsevier BVVol: 102Issue #:Start Page: 105065End Page: 105065Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1016/j.ebiom.2024.105065Best OA location URL: http://www.thelancet.com/article/S2352396424001002/pdfCitation Count: 7
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RESTRICTEDTitle: Importance of the initial response to GPi deep brain stimulation in dystonia: A nine year quality of life studyJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 64Issue #:Start Page: 249End Page: 255Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.04.024Citation Count: 26
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OPENTitle: Tackling underrepresentation to aid understanding of Parkinson’s disease: Progress and further opportunitiesJournal Name: Physiology NewsPublisher: The Physiological SocietyVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.36866/pn.123.32Best OA location URL: https://static.physoc.org/app/uploads/2021/09/29101854/PN123_2709_WEB_FINAL.pdfCitation Count: 0