5601 - 5650 of 8620 Results
Title
Year
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OPENTitle: Current and projected future economic burden of Parkinson’s disease in the U.S.Journal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-020-0117-1Best OA location URL: https://escholarship.org/content/qt6wh3b5bz/qt6wh3b5bz.pdfCitation Count: 495
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OPENTitle: Limb and trunk accelerometer data collected with wearable sensors from subjects with Parkinson’s diseaseJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41597-021-00831-zBest OA location URL: https://www.nature.com/articles/s41597-021-00831-z.pdfCitation Count: 12
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OPENTitle: Six Action Steps to Address Global Disparities in Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 79Issue #: 9Start Page: 929End Page: 929Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2022.1783Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2793874/jamaneurology_schiess_2022_sc_220001_1662471546.98796.pdfCitation Count: 95
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OPENTitle: Profiling migraine patients according to clinical and psychophysical characteristics: clinical validity of distinct migraine clustersJournal Name: Neurological SciencesPublisher: Springer Science and Business Media LLCVol: 45Issue #: 3Start Page: 1185End Page: 1200Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s10072-023-07118-8Best OA location URL: https://link.springer.com/content/pdf/10.1007/s10072-023-07118-8.pdfCitation Count: 5
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OPENTitle: Anodal tDCS modulates cortical activity and synchronization in Parkinson's disease depending on motor processingJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 22Issue #:Start Page: 101689End Page: 101689Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101689Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101689Citation Count: 23
- Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s disease2016RESTRICTEDTitle: Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s diseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 8Issue #: 360Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.aad8858Citation Count: 68
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OPENTitle: Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementiaJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 147Issue #: 10Start Page: 3547End Page: 3561Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awae140Best OA location URL: https://doi.org/10.1093/brain/awae140Citation Count: 5
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OPENTitle: Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control CasesJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 9Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2015.00507Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2015.00507/pdfCitation Count: 35
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OPENTitle: Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson’s modelsJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 136Issue #: 4Start Page: 607End Page: 620Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-018-1873-4Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6123262Citation Count: 132
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OPENTitle: Automated, multiparametric monitoring of respiratory biomarkers and vital signs in clinical and home settings for COVID-19 patientsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 118Issue #: 19Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1073/pnas.2026610118Best OA location URL: https://escholarship.org/content/qt1p8123ct/qt1p8123ct.pdfCitation Count: 86
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OPENTitle: ZEBRA: a hierarchically integrated gene expression atlas of the murine and human brain at single-cell resolutionJournal Name: Nucleic Acids ResearchPublisher: Oxford University Press (OUP)Vol: 52Issue #: D1Start Page: D1089End Page: D1096Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/nar/gkad990Best OA location URL: https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkad990/52947155/gkad990.pdfCitation Count: 4
- Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases2021OPENTitle: Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligasesJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 16Issue #: 10Start Page: e0258315End Page: e0258315Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0258315Best OA location URL: https://doi.org/10.1371/journal.pone.0258315Citation Count: 16
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OPENTitle: Lifestyle factors and clinical severity of Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-023-31531-wBest OA location URL: https://www.nature.com/articles/s41598-023-31531-w.pdfCitation Count: 11
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OPENTitle: Tau immunoreactivity in peripheral tissues of human aging and select tauopathiesJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 696Issue #:Start Page: 132End Page: 139Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2018.12.031Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7357994Citation Count: 49
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OPENTitle: α‐Synuclein in blood cells differentiates Parkinson’s disease from healthy controlsJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 6Issue #: 12Start Page: 2426End Page: 2436Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/acn3.50944Best OA location URL: https://hdl.handle.net/11384/134333Citation Count: 35
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OPENTitle: Identification of a Putative α-synuclein Radioligand Using an in silico Similarity SearchJournal Name: Molecular Imaging and BiologyPublisher: Springer Science and Business Media LLCVol: 25Issue #: 4Start Page: 704End Page: 719Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11307-023-01814-9Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10527666Citation Count: 9
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OPENTitle: Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injuryJournal Name: EMBO Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 15Issue #: 12Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.15252/emmm.202317907Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/emmm.202317907Citation Count: 31
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OPENTitle: Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degenerationJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-022-31869-1Best OA location URL: https://www.nature.com/articles/s41467-022-31869-1.pdfCitation Count: 28
- Remote Monitoring of Treatment Response in Parkinson's Disease: The Habit of Typing on a Computer2019OPENTitle: Remote Monitoring of Treatment Response in Parkinson's Disease: The Habit of Typing on a ComputerJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 10Start Page: 1488End Page: 1495Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27772Citation Count: 37
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OPENTitle: Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson’s diseaseJournal Name: Molecular Therapy - Nucleic AcidsPublisher: Elsevier BVVol: 28Issue #:Start Page: 1End Page: 15Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.omtn.2022.02.007Best OA location URL: https://doi.org/10.1016/j.omtn.2022.02.007Citation Count: 20
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OPENTitle: LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patientsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-019-13413-wBest OA location URL: https://www.nature.com/articles/s41467-019-13413-w.pdfCitation Count: 170
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OPENTitle: Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional studyJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 22Issue #: 5Start Page: 407End Page: 417Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s1474-4422(23)00109-6Best OA location URL: https://resolver.sub.uni-goettingen.de/purl?gro-2/133500Citation Count: 440
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OPENTitle: Thermodynamic characterization of amyloid polymorphism by microfluidic transient incomplete separationJournal Name: Chemical SciencePublisher: Royal Society of Chemistry (RSC)Vol: 15Issue #: 7Start Page: 2528End Page: 2544Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1039/d3sc05371gBest OA location URL: https://pubs.rsc.org/en/content/articlepdf/2024/sc/d3sc05371gCitation Count: 13
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OPENTitle: Orientation selective deep brain stimulationJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 14Issue #: 1Start Page: 016016End Page: 016016Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1088/1741-2552/aa5238Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5440185Citation Count: 48
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RESTRICTEDTitle: Physiotherapy improves motor function in patients with the Parkinson variant of multiple system atrophy: A prospective trialJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 67Issue #:Start Page: 60End Page: 65Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.09.026Citation Count: 32
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RESTRICTEDTitle: Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson modelJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 219Issue #: 1Start Page: 298End Page: 307Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2009.05.033Citation Count: 93
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OPENTitle: Differences in the Presentation and Progression of Parkinson's Disease by SexJournal Name: Movement DisordersPublisher: WileyVol: 36Issue #: 1Start Page: 106End Page: 117Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.28312Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28312Citation Count: 79
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OPENTitle: Long-Term Dementia Risk in Parkinson DiseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 103Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000209699Best OA location URL: https://escholarship.org/content/qt59g3g428/qt59g3g428.pdfCitation Count: 21
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OPENTitle: Anxiety in Parkinson's disease is associated with changes in the brain fear circuitJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 80Issue #:Start Page: 89End Page: 97Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2020.09.020Best OA location URL: http://www.prd-journal.com/article/S1353802020307343/pdfCitation Count: 29
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OPENTitle: LRRK2 activation in idiopathic Parkinson’s diseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 10Issue #: 451Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.aar5429Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6344941Citation Count: 547
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OPENTitle: MR‐based age‐related effects on the striatum, globus pallidus, and thalamus in healthy individuals across the adult lifespanJournal Name: Human Brain MappingPublisher: WileyVol: 40Issue #: 18Start Page: 5269End Page: 5288Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1002/hbm.24771Best OA location URL: https://doi.org/10.1002/hbm.24771Citation Count: 68
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OPENTitle: Elevation of gangliosides in four brain regions from Parkinson’s disease patients with a GBA mutationJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-022-00363-2Best OA location URL: https://www.nature.com/articles/s41531-022-00363-2.pdfCitation Count: 16
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OPENTitle: Missing Drivers with Dementia: Antecedents and RecoveryJournal Name: Journal of the American Geriatrics SocietyPublisher: WileyVol: 60Issue #: 11Start Page: 2063End Page: 2069Publication Date:Open Access(OA) Status: OPENLicense: public-domainDOI - Digital Object Identifier: 10.1111/j.1532-5415.2012.04159.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1532-5415.2012.04159.xCitation Count: 20
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OPENTitle: Clinical and Neuropathological Features Associated With Loss of RAB39BJournal Name: Movement DisordersPublisher: WileyVol: 35Issue #: 4Start Page: 687End Page: 693Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27951Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.27951Citation Count: 18
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OPENTitle: Alpha‐synuclein RT‐QuIC in the CSF of patients with alpha‐synucleinopathiesJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 3Issue #: 10Start Page: 812End Page: 818Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/acn3.338Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.338Citation Count: 479
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OPENTitle: Cellular localization of p-tau217 in brain and its association with p-tau217 plasma levelsJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-021-01307-2Best OA location URL: https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-021-01307-2Citation Count: 51
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OPENTitle: Diabetes is associated with postural instability and gait difficulty in Parkinson diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 19Issue #: 5Start Page: 522End Page: 526Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2013.01.016Best OA location URL: http://doi.org/10.1016/j.parkreldis.2013.01.016Citation Count: 108
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OPENTitle: High complement levels in astrocyte‐derived exosomes of Alzheimer diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 83Issue #: 3Start Page: 544End Page: 552Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25172Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5867263Citation Count: 314
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OPENTitle: Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPasesJournal Name: Journal of Cell BiologyPublisher: Rockefeller University PressVol: 218Issue #: 12Start Page: 4157End Page: 4170Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-saDOI - Digital Object Identifier: 10.1083/jcb.201902184Best OA location URL: https://rupress.org/jcb/article-pdf/218/12/4157/1395522/jcb_201902184.pdfCitation Count: 102
- Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation2019OPENTitle: Local vulnerability and global connectivity jointly shape neurodegenerative disease propagationJournal Name: PLOS BiologyPublisher: Public Library of Science (PLoS)Vol: 17Issue #: 11Start Page: e3000495End Page: e3000495Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pbio.3000495Best OA location URL: https://doi.org/10.1371/journal.pbio.3000495Citation Count: 124
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OPENTitle: Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational effortsJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 140Issue #: 6Start Page: 1544End Page: 1547Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awx107Best OA location URL: https://academic.oup.com/brain/article-pdf/140/6/1544/18186427/awx107.pdfCitation Count: 18
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OPENTitle: Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot ProteomicsJournal Name: Molecular CellPublisher: Elsevier BVVol: 70Issue #: 2Start Page: 211End Page: 227.e8Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1016/j.molcel.2018.03.012Best OA location URL: http://www.cell.com/article/S1097276518302156/pdfCitation Count: 173
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OPENTitle: Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activityJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 477Issue #: 22Start Page: 4397End Page: 4423Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bcj20200458Best OA location URL: https://portlandpress.com/biochemj/article-pdf/477/22/4397/898287/bcj-2020-0458.pdfCitation Count: 67
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OPENTitle: High-resolution local field potentials measured with deep brain stimulation arraysJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 15Issue #: 4Start Page: 046019End Page: 046019Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1088/1741-2552/aabdf5Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6021212Citation Count: 16
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OPENTitle: Impaired hepatic amyloid-beta degradation in Alzheimer’s diseaseJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 13Issue #: 9Start Page: e0203659End Page: e0203659Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0203659Best OA location URL: https://doi.org/10.1371/journal.pone.0203659Citation Count: 70
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RESTRICTEDTitle: Intranasal delivery of hGDNF plasmid DNA nanoparticles results in long-term and widespread transfection of perivascular cells in rat brainJournal Name: Nanomedicine: Nanotechnology, Biology and MedicinePublisher: Elsevier BVVol: 16Issue #:Start Page: 20End Page: 33Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.nano.2018.11.006Citation Count: 26
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OPENTitle: The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Nav 1.6Journal Name: Experimental NeurologyPublisher: Elsevier BVVol: 308Issue #:Start Page: 111End Page: 119Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2018.07.005Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7404626Citation Count: 38
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OPENTitle: Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson diseaseJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 2Issue #: 10Start Page: 949End Page: 959Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.246Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.246Citation Count: 178
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OPENTitle: Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagyJournal Name: Journal of Cell SciencePublisher: The Company of BiologistsVol: 134Issue #: 4Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1242/jcs.256255Best OA location URL: https://journals.biologists.com/jcs/article-pdf/134/4/jcs256255/1822504/jcs256255.pdfCitation Count: 51
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RESTRICTEDTitle: A cognitive fMRI study in non-manifesting LRRK2 and GBA carriersJournal Name: Brain Structure and FunctionPublisher: Springer Science and Business Media LLCVol: 222Issue #: 3Start Page: 1207End Page: 1218Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s00429-016-1271-4Citation Count: 21