6401 - 6450 of 8808 Results
Title
Year
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OPENTitle: O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's diseaseJournal Name: Nature ChemistryPublisher: Springer Science and Business Media LLCVol: 7Issue #: 11Start Page: 913End Page: 920Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nchem.2361Best OA location URL: http://doi.org/10.1038/nchem.2361Citation Count: 253
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OPENTitle: Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging InitiativeJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 68Issue #: 1Start Page: 58End Page: 58Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2010.343Citation Count: 151
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OPENTitle: Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicityJournal Name: Molecular BrainPublisher: Springer Science and Business Media LLCVol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1756-6606-1-17Best OA location URL: https://molecularbrain.biomedcentral.com/counter/pdf/10.1186/1756-6606-1-17Citation Count: 244
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OPENTitle: LRRK2 secretion in exosomes is regulated by 14-3-3Journal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 22Issue #: 24Start Page: 4988End Page: 5000Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddt346Best OA location URL: https://academic.oup.com/hmg/article-pdf/22/24/4988/14140078/ddt346.pdfCitation Count: 161
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OPENTitle: Integrated molecular landscape of Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0015-3Best OA location URL: https://pub.dzne.de/search?p=id:%22DZNE-2020-01126%22Citation Count: 118
- Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation2009OPENTitle: Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradationJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 119Issue #: 3Start Page: 650End Page: 660Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci37617Best OA location URL: http://doi.org/10.1172/JCI37617Citation Count: 376
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OPENTitle: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 47Start Page: 18754End Page: 18759Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0704908104Best OA location URL: http://doi.org/10.1073/pnas.0704908104Citation Count: 416
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OPENTitle: LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's diseaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 40Issue #: 1Start Page: 73End Page: 81Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.04.002Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2926296Citation Count: 143
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OPENTitle: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasisJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 114Issue #: 5Start Page: 1165End Page: 1170Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1522872114Best OA location URL: https://www.pnas.org/content/pnas/114/5/1165.full.pdfCitation Count: 115
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OPENTitle: Involvement of Perineuronal and Perisynaptic Extracellular Matrix in Alzheimer's Disease NeuropathologyJournal Name: Brain PathologyPublisher: WileyVol: 22Issue #: 4Start Page: 547End Page: 561Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1750-3639.2011.00557.xBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3639011Citation Count: 146
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OPENTitle: Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 29Start Page: 12175End Page: 12180Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0704091104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0704091104Citation Count: 347
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OPENTitle: Loss-of-function mutations in theATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)Journal Name: BrainPublisher: Oxford University Press (OUP)Vol: 140Issue #: 2Start Page: 287End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/aww307Best OA location URL: https://academic.oup.com/brain/article-pdf/140/2/287/24174630/aww307.pdfCitation Count: 153
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OPENTitle: Use of ibuprofen and risk of Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 10Start Page: 863End Page: 869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820f2d79Best OA location URL: https://n.neurology.org/content/neurology/76/10/863.full.pdfCitation Count: 316
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OPENTitle: Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patientsJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 121Issue #: 3Start Page: 930End Page: 940Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci43871Citation Count: 152
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OPENTitle: A GCase Chaperone Improves Motor Function in a Mouse Model of SynucleinopathyJournal Name: NeurotherapeuticsPublisher: Elsevier BVVol: 11Issue #: 4Start Page: 840End Page: 856Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s13311-014-0294-xBest OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-014-0294-x.pdfCitation Count: 98
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OPENTitle: Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 106Issue #: 36Start Page: 15454End Page: 15459Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0813216106Best OA location URL: http://doi.org/10.1073/pnas.0813216106Citation Count: 260
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OPENTitle: Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's DiseaseJournal Name: PLoS GeneticsPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 6Start Page: e1002141End Page: e1002141Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pgen.1002141Best OA location URL: https://escholarship.org/uc/item/1zw763wgCitation Count: 520
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OPENTitle: Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson’s diseaseJournal Name: Journal of NeurochemistryPublisher: WileyVol: 100Issue #: 6Start Page: 1469End Page: 1479Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2006.04333.xBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8669833Citation Count: 343
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OPENTitle: Mechanism and regulation of the Lys6-selective deubiquitinase USP30Journal Name: Nature Structural & Molecular BiologyPublisher: Springer Science and Business Media LLCVol: 24Issue #: 11Start Page: 920End Page: 930Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nsmb.3475Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5757785Citation Count: 201
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OPENTitle: Clinical signs in functional (psychogenic) gait disorders: a brief surveyJournal Name: Journal of Clinical Movement DisordersPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40734-016-0031-1Best OA location URL: https://clinicalmovementdisorders.biomedcentral.com/counter/pdf/10.1186/s40734-016-0031-1Citation Count: 23
- Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease2018OPENTitle: Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s DiseaseJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/sdata.2018.36Best OA location URL: https://www.nature.com/articles/sdata201836.pdfCitation Count: 215
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OPENTitle: Sarcopenia and impairment in cognitive and physical performanceJournal Name: Clinical Interventions in AgingPublisher: Informa UK LimitedVol:Issue #:Start Page: 663End Page: 663Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.2147/cia.s76275Best OA location URL: https://www.dovepress.com/getfile.php?fileID=24358Citation Count: 98
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OPENTitle: 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localizationJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 430Issue #: 3Start Page: 393End Page: 404Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1042/bj20100483Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/393/878058/bj4300393.pdfCitation Count: 385
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OPENTitle: Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localizationJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 430Issue #: 3Start Page: 405End Page: 413Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bj20100784Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/405/664434/bj4300405.pdfCitation Count: 377
- Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining2012OPENTitle: Toward modernizing the systematic review pipeline in genetics: efficient updating via data miningJournal Name: Genetics in MedicinePublisher: Elsevier BVVol: 14Issue #: 7Start Page: 663End Page: 669Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/gim.2012.7Best OA location URL: http://www.gimjournal.org/article/S1098360021022863/pdfCitation Count: 60
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OPENTitle: Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s DiseaseJournal Name: Molecular NeurobiologyPublisher: Springer Science and Business Media LLCVol: 55Issue #: 11Start Page: 8592End Page: 8601Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s12035-018-0977-0Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6677544Citation Count: 70
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OPENTitle: Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative diseaseJournal Name: Journal of Comparative NeurologyPublisher: WileyVol: 515Issue #: 3Start Page: 269End Page: 294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/cne.22040Best OA location URL: http://doi.org/10.1002/cne.22040Citation Count: 55
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OPENTitle: Phosphorylation of 4E-BP1 in the Mammalian Brain Is Not Altered by LRRK2 Expression or Pathogenic MutationsJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 10Start Page: e47784End Page: e47784Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0047784Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0047784&type=printableCitation Count: 41
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OPENTitle: The human subthalamic nucleus and globus pallidus internus differentially encode reward during action controlJournal Name: Human Brain MappingPublisher: WileyVol: 38Issue #: 4Start Page: 1952End Page: 1964Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/hbm.23496Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.23496Citation Count: 29
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OPENTitle: 18F‐flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter studyJournal Name: Annals of NeurologyPublisher: WileyVol: 82Issue #: 4Start Page: 622End Page: 634Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25060Best OA location URL: https://escholarship.org/uc/item/01j9450zCitation Count: 164
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OPENTitle: Methylphenidate for gait impairment in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 14Start Page: 1256End Page: 1262Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182143537Best OA location URL: https://n.neurology.org/content/neurology/76/14/1256.full.pdfCitation Count: 92
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OPENTitle: Behavioral and histopathological consequences of paraquat intoxication in mice: Effects of α‐synuclein over‐expressionJournal Name: SynapsePublisher: WileyVol: 61Issue #: 12Start Page: 991End Page: 1001Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/syn.20456Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3097512Citation Count: 183
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OPENTitle: Consumption of Dairy Products and Risk of Parkinson's DiseaseJournal Name: American Journal of EpidemiologyPublisher: Oxford University Press (OUP)Vol: 165Issue #: 9Start Page: 998End Page: 1006Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/aje/kwk089Best OA location URL: https://academic.oup.com/aje/article-pdf/165/9/998/204475/kwk089.pdfCitation Count: 184
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OPENTitle: Model-based and Model-free Machine Learning Techniques for Diagnostic Prediction and Classification of Clinical Outcomes in Parkinson’s DiseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-018-24783-4Best OA location URL: https://www.nature.com/articles/s41598-018-24783-4.pdfCitation Count: 173
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OPENTitle: Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairmentJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 120Issue #: 6Start Page: 827End Page: 828Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-010-0744-4Citation Count: 84
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OPENTitle: Activity enhances dopaminergic long-duration response in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 78Issue #: 15Start Page: 1146End Page: 1149Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31824f8056Best OA location URL: https://n.neurology.org/content/neurology/78/15/1146.full.pdfCitation Count: 28
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OPENTitle: Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysisJournal Name: Journal of Neurology, Neurosurgery & PsychiatryPublisher: BMJVol: 82Issue #: 5Start Page: 564End Page: 568Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1136/jnnp.2010.222042Citation Count: 100
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OPENTitle: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseasesJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/sdata.2016.89Best OA location URL: https://www.nature.com/articles/sdata201689.pdfCitation Count: 427
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OPENTitle: Latent growth-curve analysis reveals that worsening Parkinson’s disease quality of life is driven by depression.Journal Name: NeuropsychologyPublisher: American Psychological Association (APA)Vol: 29Issue #: 4Start Page: 603End Page: 609Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1037/neu0000158Best OA location URL: http://doi.org/10.1037/neu0000158Citation Count: 20
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OPENTitle: NEDD4-mediated HSF1 degradation underlies α-synucleinopathyJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 25Issue #: 2Start Page: 211End Page: 222Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/hmg/ddv445Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/2/211/18526601/ddv445.pdfCitation Count: 84
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OPENTitle: M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced DyskinesiaJournal Name: NeuronPublisher: Elsevier BVVol: 88Issue #: 4Start Page: 762End Page: 773Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuron.2015.10.039Best OA location URL: http://www.cell.com/article/S0896627315009332/pdfCitation Count: 219
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OPENTitle: Genetic analysis of the FUS/TLS gene in essential tremorJournal Name: European Journal of NeurologyPublisher: WileyVol: 20Issue #: 3Start Page: 534End Page: 539Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ene.12023Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4862621Citation Count: 35
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OPENTitle: PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrityJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 21Issue #: 8Start Page: 1725End Page: 1743Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddr606Best OA location URL: https://academic.oup.com/hmg/article-pdf/21/8/1725/17258592/ddr606.pdfCitation Count: 159
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OPENTitle: Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1Journal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 7Issue #: 46Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by, cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.abj0722Best OA location URL: https://www.science.org/doi/pdf/10.1126/sciadv.abj0722?download=trueCitation Count: 56
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OPENTitle: Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic miceJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 40Issue #: 3Start Page: 503End Page: 517Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.07.010Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2955774Citation Count: 266
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OPENTitle: Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disordersJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 119Issue #: 6Start Page: 689End Page: 702Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-010-0664-3Citation Count: 795
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OPENTitle: Tau positron emission tomographic imaging in aging and early Alzheimer diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 79Issue #: 1Start Page: 110End Page: 119Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.24546Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.24546Citation Count: 878
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OPENTitle: Improving the clinical detection of Lewy body dementia with the Lewy body composite risk scoreJournal Name: Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringPublisher: WileyVol: 1Issue #: 3Start Page: 316End Page: 324Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.dadm.2015.05.004Best OA location URL: https://doi.org/10.1016/j.dadm.2015.05.004Citation Count: 74
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OPENTitle: Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body diseaseJournal Name: AutophagyPublisher: Informa UK LimitedVol: 14Issue #: 8Start Page: 1404End Page: 1418Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/15548627.2018.1461294Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15548627.2018.1461294?needAccess=trueCitation Count: 121
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OPENTitle: Submandibular Gland Biopsy for the Diagnosis of Parkinson DiseaseJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 72Issue #: 2Start Page: 130End Page: 136Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0b013e3182805c72Best OA location URL: https://academic.oup.com/jnen/article-pdf/72/2/130/9562462/72-2-130.pdfCitation Count: 113