6751 - 6800 of 8808 Results
Title
Year
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OPENTitle: Human plasma biomarker responses to inhalational general anaesthesia without surgeryJournal Name: British Journal of AnaesthesiaPublisher: Elsevier BVVol: 125Issue #: 3Start Page: 282End Page: 290Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bja.2020.04.085Best OA location URL: http://www.bjanaesthesia.org/article/S0007091220303391/pdfCitation Count: 40
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OPENTitle: Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD SamplesJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 13Issue #:Start Page: 704041End Page: 704041Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2021.704041Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2021.704041/pdfCitation Count: 23
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OPENTitle: Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 119Issue #: 11Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1073/pnas.2121609119Best OA location URL: https://escholarship.org/uc/item/4pt523rvCitation Count: 40
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OPENTitle: Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2023 UpdateJournal Name: Journal of Parkinson’s DiseasePublisher: SAGE PublicationsVol: 13Issue #: 4Start Page: 427End Page: 439Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-239901Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd239901?id=journal-of-parkinsons-disease%2Fjpd239901Citation Count: 62
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OPENTitle: ATP13A3 is a major component of the enigmatic mammalian polyamine transport systemJournal Name: Journal of Biological ChemistryPublisher: Elsevier BVVol: 296Issue #:Start Page: 100182End Page: 100182Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1074/jbc.ra120.013908Best OA location URL: http://www.jbc.org/article/S0021925820001787/pdfCitation Count: 69
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OPENTitle: Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the BrainJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 12Issue #: 23Start Page: 4465End Page: 4474Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1021/acschemneuro.1c00641Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8640995Citation Count: 26
- Longitudinal analyses of cerebrospinal fluid α‐Synuclein in prodromal and early Parkinson's disease2019OPENTitle: Longitudinal analyses of cerebrospinal fluid α‐Synuclein in prodromal and early Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 9Start Page: 1354End Page: 1364Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.27806Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.27806Citation Count: 110
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OPENTitle: DeepSleep convolutional neural network allows accurate and fast detection of sleep arousalJournal Name: Communications BiologyPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s42003-020-01542-8Best OA location URL: https://www.nature.com/articles/s42003-020-01542-8.pdfCitation Count: 39
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OPENTitle: Predicting Progression in Parkinson’s Disease Using Baseline and 1-Year Change MeasuresJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 9Issue #: 4Start Page: 665End Page: 679Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-181518Best OA location URL: https://escholarship.org/uc/item/2w68g45qCitation Count: 20
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RESTRICTEDTitle: Longitudinal changes in CSF alpha‐synuclein species reflect Parkinson's disease progressionJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 10Start Page: 1535End Page: 1542Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26754Citation Count: 140
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OPENTitle: Neuromelanin accumulation drives endogenous synucleinopathy in non-human primatesJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 146Issue #: 12Start Page: 5000End Page: 5014Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1093/brain/awad331Best OA location URL: https://academic.oup.com/brain/advance-article-pdf/doi/10.1093/brain/awad331/51792215/awad331.pdfCitation Count: 16
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OPENTitle: Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson diseaseJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 303Issue #:Start Page: 95End Page: 107Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2018.01.015Citation Count: 39
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OPENTitle: The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseasesJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 14Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-023-42305-3Best OA location URL: https://www.nature.com/articles/s41467-023-42305-3.pdfCitation Count: 64
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OPENTitle: GP2: The Global Parkinson's Genetics ProgramJournal Name: Movement DisordersPublisher: WileyVol: 36Issue #: 4Start Page: 842End Page: 851Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1002/mds.28494Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28494Citation Count: 129
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RESTRICTEDTitle: Media hype: Patient and scientific perspectives on misleading medical newsJournal Name: Movement DisordersPublisher: WileyVol: 32Issue #: 9Start Page: 1319End Page: 1323Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26993Citation Count: 44
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OPENTitle: Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in RodentsJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 8Issue #: 2Start Page: 303End Page: 322Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-171248Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd171248?id=journal-of-parkinsons-disease%2Fjpd171248Citation Count: 234
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OPENTitle: The Remote Assessment of Parkinsonism Supporting the Ongoing Development of Interventions in Gaucher DiseaseJournal Name: Neurodegenerative Disease ManagementPublisher: Informa UK LimitedVol: 11Issue #: 6Start Page: 451End Page: 458Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.2217/nmt-2021-0032Best OA location URL: https://doi.org/10.2217/nmt-2021-0032Citation Count: 14
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OPENTitle: Pedunculopontine Nucleus Dysconnectivity Correlates With Gait Impairment in Parkinson’s Disease: An Exploratory StudyJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 14Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2022.874692Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2022.874692/pdfCitation Count: 7
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OPENTitle: Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injuryJournal Name: EMBO Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 15Issue #: 12Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.15252/emmm.202317907Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/emmm.202317907Citation Count: 31
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OPENTitle: Associations of cholinergic system integrity with cognitive decline in GBA1 and LRRK2 mutation carriersJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-024-00743-wBest OA location URL: https://www.nature.com/articles/s41531-024-00743-w.pdfCitation Count: 2
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OPENTitle: Oligomeric α‐synuclein and β‐amyloid variants as potential biomarkers for Parkinson's and Alzheimer's diseasesJournal Name: European Journal of NeurosciencePublisher: WileyVol: 43Issue #: 1Start Page: 3End Page: 16Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ejn.13056Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ejn.13056Citation Count: 68
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OPENTitle: Gut microbiome-derived tryptophan metabolites predict relapse in alcohol use disorderJournal Name: Brain, Behavior, and ImmunityPublisher: Elsevier BVVol: 131Issue #:Start Page: 106161End Page: 106161Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bbi.2025.106161Best OA location URL: https://doi.org/10.1016/j.bbi.2025.106161Citation Count: 0
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OPENTitle: Healthcare access and utilization of deep brain stimulation and supplementary care in black and white patients with Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 140Issue #:Start Page: 108057End Page: 108057Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.parkreldis.2025.108057Best OA location URL: https://doi.org/10.1016/j.parkreldis.2025.108057Citation Count: 0
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RESTRICTEDTitle: Dystonia as complication of thalamic neurosurgeryJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 66Issue #:Start Page: 232End Page: 236Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.08.008Citation Count: 24
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OPENTitle: A New Dataset for Facial Motion Analysis in Individuals With Neurological DisordersJournal Name: IEEE Journal of Biomedical and Health InformaticsPublisher: Institute of Electrical and Electronics Engineers (IEEE)Vol: 25Issue #: 4Start Page: 1111End Page: 1119Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1109/jbhi.2020.3019242Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8062040Citation Count: 53
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OPENTitle: ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagyJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 118Issue #: 24Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1073/pnas.2025053118Best OA location URL: https://doi.org/10.1073/pnas.2025053118Citation Count: 83
- The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN212018OPENTitle: The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21Journal Name: Cell ReportsPublisher: Elsevier BVVol: 25Issue #: 9Start Page: 2484End Page: 2496.e9Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.celrep.2018.11.002Best OA location URL: http://www.cell.com/article/S2211124718317315/pdfCitation Count: 36
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OPENTitle: VPS13D bridges the ER to mitochondria and peroxisomes via MiroJournal Name: Journal of Cell BiologyPublisher: Rockefeller University PressVol: 220Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-sa, cc-by-nc-sa, cc-by-nc-saDOI - Digital Object Identifier: 10.1083/jcb.202010004Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8077184Citation Count: 146
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OPENTitle: A machine learning contest enhances automated freezing of gait detection and reveals time-of-day effectsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page: 4853End Page: 4853Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-024-49027-0Best OA location URL: https://www.nature.com/articles/s41467-024-49027-0.pdfCitation Count: 26
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RESTRICTEDTitle: More than constipation – bowel symptoms in Parkinson's disease and their connection to gut microbiotaJournal Name: European Journal of NeurologyPublisher: WileyVol: 24Issue #: 11Start Page: 1375End Page: 1383Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/ene.13398Citation Count: 141
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OPENTitle: Orthostatic hypotension in Parkinson disease: Impact on health care utilizationJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 47Issue #:Start Page: 45End Page: 49Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.11.344Best OA location URL: https://zenodo.org/record/3830895Citation Count: 40
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OPENTitle: Development and validation of a sensitive sandwich ELISA against human PINK1Journal Name: AutophagyPublisher: Informa UK LimitedVol: 21Issue #: 5Start Page: 1End Page: 16Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1080/15548627.2025.2457915Best OA location URL: https://doi.org/10.1080/15548627.2025.2457915Citation Count: 2
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OPENTitle: Hippocampal CA1 subfield predicts episodic memory impairment in Parkinson's diseaseJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 23Issue #:Start Page: 101824End Page: 101824Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101824Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101824Citation Count: 59
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OPENTitle: Characterization of Small-Molecule-Induced Changes in Parkinson's-Related Trafficking via the Nedd4 Ubiquitin Signaling CascadeJournal Name: Cell Chemical BiologyPublisher: Elsevier BVVol: 28Issue #: 1Start Page: 14End Page: 25.e9Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1016/j.chembiol.2020.10.008Best OA location URL: http://www.cell.com/article/S2451945620304244/pdfCitation Count: 17
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OPENTitle: Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9Journal Name: Gene TherapyPublisher: Springer Science and Business Media LLCVol: 29Issue #: 6Start Page: 390End Page: 397Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41434-021-00244-yBest OA location URL: https://www.nature.com/articles/s41434-021-00244-y.pdfCitation Count: 36
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OPENTitle: The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarizationJournal Name: Biology OpenPublisher: The Company of BiologistsVol: 11Issue #: 8Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1242/bio.059468Best OA location URL: https://journals.biologists.com/bio/article-pdf/11/8/bio059468/2155235/bio059468.pdfCitation Count: 24
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OPENTitle: Cholinergic innervation topography in GBA-associated de novo Parkinson’s disease patientsJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 147Issue #: 3Start Page: 900End Page: 910Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/brain/awad323Best OA location URL: https://academic.oup.com/brain/advance-article-pdf/doi/10.1093/brain/awad323/51752208/awad323.pdfCitation Count: 13
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OPENTitle: Predicting Post‐Mortem α‐Synuclein Pathology by the Combined Presence of Probable REM sleep behavior disorder and HyposmiaJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 12Issue #: 2Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/mdc3.14244Best OA location URL: https://doi.org/10.1002/mdc3.14244Citation Count: 3
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OPENTitle: Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in miceJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 6Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.28377Best OA location URL: https://doi.org/10.7554/elife.28377Citation Count: 96
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OPENTitle: Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicityJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 137Issue #: 6Start Page: 939End Page: 960Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-019-01993-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-019-01993-2.pdfCitation Count: 76
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OPENTitle: KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicityJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 31Start Page: 9596End Page: 9601Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1505953112Best OA location URL: https://www.pnas.org/content/pnas/112/31/9596.full.pdfCitation Count: 153
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OPENTitle: Motor skill learning modulates striatal extracellular vesicles’ content in a mouse model of Huntington’s diseaseJournal Name: Cell Communication and SignalingPublisher: Springer Science and Business Media LLCVol: 22Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12964-024-01693-9Best OA location URL: https://biosignaling.biomedcentral.com/counter/pdf/10.1186/s12964-024-01693-9Citation Count: 1
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OPENTitle: PINK1 phosphorylates ubiquitin predominantly in astrocytesJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-019-0101-9Best OA location URL: https://www.nature.com/articles/s41531-019-0101-9.pdfCitation Count: 40
- Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans2024OPENTitle: Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in transJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 13Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.96699.3Best OA location URL: https://doi.org/10.7554/elife.96699.3Citation Count: 3
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OPENTitle: Pure Autonomic Failure Versus Prodromal Dysautonomia in Parkinson's Disease: Insights from the BedsideJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 4Issue #: 1Start Page: 141End Page: 144Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12360Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12360Citation Count: 12
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OPENTitle: Olfactory Bulb Amyloid-β Correlates With Brain Thal Amyloid Phase and Severity of Cognitive ImpairmentJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 81Issue #: 8Start Page: 643End Page: 649Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/jnen/nlac042Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9297096Citation Count: 8
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OPENTitle: Separation of Subcutaneous Fat From Muscle in Surface Electrical Impedance Myography Measurements Using Model Component AnalysisJournal Name: IEEE Transactions on Biomedical EngineeringPublisher: Institute of Electrical and Electronics Engineers (IEEE)Vol: 66Issue #: 2Start Page: 354End Page: 364Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1109/tbme.2018.2839977Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6357232Citation Count: 20
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RESTRICTEDTitle: Higher urate in LRRK2 mutation carriers resistant to Parkinson diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 85Issue #: 4Start Page: 593End Page: 599Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/ana.25436Citation Count: 52
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OPENTitle: Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disordersJournal Name: AutophagyPublisher: Informa UK LimitedVol:Issue #:Start Page: 1End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/15548627.2025.2581217Best OA location URL: https://doi.org/10.1080/15548627.2025.2581217Citation Count: 0
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OPENTitle: α‐Synuclein stimulation of monoamine oxidase‐B and legumain protease mediates the pathology of Parkinson's diseaseJournal Name: The EMBO JournalPublisher: Springer Science and Business Media LLCVol: 37Issue #: 12Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.15252/embj.201798878Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.201798878Citation Count: 84