7601 - 7650 of 7939 Results
Title
Year
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OPENTitle: MAPT H1 haplotype is a risk factor for essential tremor and multiple system atrophyJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 7Start Page: 670End Page: 672Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820c30c1Best OA location URL: https://europepmc.org/articles/pmc3053340?pdf=renderCitation Count: 70
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OPENTitle: Substantia nigra hyperechogenicity with LRRK2 G2019S mutationsJournal Name: Movement DisordersPublisher: WileyVol: 26Issue #: 5Start Page: 885End Page: 888Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23644Best OA location URL: https://europepmc.org/articles/pmc3082617?pdf=renderCitation Count: 34
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OPENTitle: Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's diseaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 42Issue #: 3Start Page: 327End Page: 340Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2011.01.024Best OA location URL: https://lup.lub.lu.se/search/files/1732507/1885514.pdfCitation Count: 160
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OPENTitle: Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanismsJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 121Issue #: 6Start Page: 705End Page: 719Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1007/s00401-011-0806-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-011-0806-2.pdfCitation Count: 54
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OPENTitle: Mitochondrial DNA haplogroups and mutations in children with acquired central demyelinationJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 9Start Page: 774End Page: 780Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820ee1bbBest OA location URL: https://europepmc.org/articles/pmc3053335?pdf=renderCitation Count: 17
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OPENTitle: Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson’s diseaseJournal Name: European Journal of NeurologyPublisher: WileyVol: 18Issue #: 5Start Page: 756End Page: 765Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1468-1331.2011.03353.xBest OA location URL: https://europepmc.org/articles/pmc3556904?pdf=renderCitation Count: 106
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OPENTitle: Essential tremor and Parkinson's disease: Lack of a linkJournal Name: Movement DisordersPublisher: WileyVol: 26Issue #: 3Start Page: 372End Page: 377Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23509Best OA location URL: https://europepmc.org/articles/pmc3070808?pdf=renderCitation Count: 59
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RESTRICTEDTitle: From reinforcement learning models to psychiatric and neurological disordersJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 14Issue #: 2Start Page: 154End Page: 162Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1038/nn.2723Best OA location URL: https://europepmc.org/articles/pmc4408000?pdf=renderCitation Count: 648
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RESTRICTEDTitle: Cyclin-G-associated kinase modifies -synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD StudyJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 20Issue #: 8Start Page: 1478End Page: 1487Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddr026Best OA location URL: https://europepmc.org/articles/pmc3063983?pdf=renderCitation Count: 61
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RESTRICTEDTitle: Prospects of Statins in Parkinson DiseaseJournal Name: The NeuroscientistPublisher: SAGE PublicationsVol: 17Issue #: 3Start Page: 244End Page: 255Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1177/1073858410385006Best OA location URL: https://europepmc.org/articles/pmc3132406?pdf=renderCitation Count: 86
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OPENTitle: Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of N-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4) with CNS Exposure in RatsJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 54Issue #: 4Start Page: 1106End Page: 1110Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/jm101271sBest OA location URL: https://europepmc.org/articles/pmc3166797?pdf=renderCitation Count: 47
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OPENTitle: Use of Florbetapir-PET for Imaging β-Amyloid PathologyJournal Name: JAMAPublisher: American Medical Association (AMA)Vol: 305Issue #: 3Start Page: 275End Page: 275Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jama.2010.2008Best OA location URL: https://europepmc.org/articles/pmc7041965?pdf=renderCitation Count: 989
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OPENTitle: α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cellsJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 121Issue #: 2Start Page: 715End Page: 725Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci43366Best OA location URL: http://www.jci.org/articles/view/43366/files/pdfCitation Count: 764
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OPENTitle: Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's diseaseJournal Name: The FASEB JournalPublisher: WileyVol: 25Issue #: 4Start Page: 1333End Page: 1344Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1096/fj.10-173625Best OA location URL: https://europepmc.org/articles/pmc3058704Citation Count: 121
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OPENTitle: Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian ratsJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 60Issue #: 6Start Page: 861End Page: 868Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2010.12.032Best OA location URL: https://europepmc.org/articles/pmc3133531?pdf=renderCitation Count: 71
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OPENTitle: Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomasJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 4Start Page: 1439End Page: 1444Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1012500108Best OA location URL: https://europepmc.org/articles/pmc3029686?pdf=renderCitation Count: 85
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OPENTitle: The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and PosiphenJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 118Issue #: 3Start Page: 493End Page: 507Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00702-010-0513-5Best OA location URL: https://europepmc.org/articles/pmc6625511?pdf=renderCitation Count: 62
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OPENTitle: Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neuronsJournal Name: Journal of Neuroscience ResearchPublisher: WileyVol: 89Issue #: 3Start Page: 406End Page: 417Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/jnr.22549Best OA location URL: https://europepmc.org/articles/pmc6487665?pdf=renderCitation Count: 16
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OPENTitle: Advances in Therapeutic Options for Gait and Balance in Parkinson’s DiseaseJournal Name: US NeurologyPublisher: Touch Medical Media, Ltd.Vol: 07Issue #: 02Start Page: 100End Page: 100Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.17925/usn.2011.07.02.100Best OA location URL: http://www.touchneurology.com/wp-content/uploads/sites/3/2015/07/private_articles_10210_pdf_chou.pdfCitation Count: 21
- Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix Compartments2011OPENTitle: Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix CompartmentsJournal Name: Frontiers in NeuroanatomyPublisher: Frontiers Media SAVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnana.2011.00059Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnana.2011.00059/pdfCitation Count: 377
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OPENTitle: Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?Journal Name: Parkinson's DiseasePublisher: Hindawi LimitedVol: 2011Issue #:Start Page: 1End Page: 9Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.4061/2011/659694Best OA location URL: https://downloads.hindawi.com/journals/pd/2011/659694.pdfCitation Count: 17
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OPENTitle: Effect of Deep Brain Stimulation on Parkinson's Nonmotor Symptoms following Unilateral DBS: A Pilot StudyJournal Name: Parkinson's DiseasePublisher: Hindawi LimitedVol: 2011Issue #:Start Page: 1End Page: 4Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.4061/2011/507416Best OA location URL: https://downloads.hindawi.com/journals/pd/2011/507416.pdfCitation Count: 28
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OPENTitle: Expert Testimony at the Food and Drug Administration: Who Wants the Truth?Journal Name: Narrative Inquiry in BioethicsPublisher: Project MUSEVol: 1Issue #: 2Start Page: 78End Page: 82Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1353/nib.2011.0046Best OA location URL: https://europepmc.org/articles/pmc4528642?pdf=renderCitation Count: 0
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OPENTitle: MicelackingRas- GRF1 showcontextualfearcondition- ing butnotspatialmemoryimpair- ments:convergentevidencefromtwo independentlygeneratedmousemutant linesJournal Name: Frontiers in Behavioral NeurosciencePublisher: Frontiers Media SAVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnbeh.2011.00078Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnbeh.2011.00078/pdfCitation Count: 35
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OPENTitle: Models for LRRK2-Linked ParkinsonismJournal Name: Parkinson's DiseasePublisher: Hindawi LimitedVol: 2011Issue #:Start Page: 1End Page: 16Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.4061/2011/942412Best OA location URL: https://downloads.hindawi.com/journals/pd/2011/942412.pdfCitation Count: 35
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OPENTitle: Pre- and Post- GPi DBS Neuropsychological Profiles in a Case of X-Linked Dystonia-ParkinsonismJournal Name: The Clinical NeuropsychologistPublisher: Informa UK LimitedVol: 25Issue #: 1Start Page: 141End Page: 159Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/13854046.2010.532812Best OA location URL: https://europepmc.org/articles/pmc3070298?pdf=renderCitation Count: 8
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OPENTitle: Ras?ERK Signaling in Behavior: Old Questions and New PerspectivesJournal Name: Frontiers in Behavioral NeurosciencePublisher: Frontiers Media SAVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnbeh.2011.00079Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnbeh.2011.00079/pdfCitation Count: 55
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OPENTitle: Rotigotine in the Long-Term Treatment of Severe RLS with Augmentation: A Series of 28 CasesJournal Name: Sleep DisordersPublisher: Hindawi LimitedVol: 2011Issue #:Start Page: 1End Page: 6Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2011/468952Best OA location URL: https://downloads.hindawi.com/journals/sd/2011/468952.pdfCitation Count: 9
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OPENTitle: Sleep Duration and “on” Time during Different Periods of the Day and Night in Patients with Advanced Parkinson's Disease Receiving Adjunctive Ropinirole Prolonged ReleaseJournal Name: Parkinson's DiseasePublisher: Hindawi LimitedVol: 2011Issue #:Start Page: 1End Page: 8Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.4061/2011/354760Best OA location URL: https://downloads.hindawi.com/journals/pd/2011/354760.pdfCitation Count: 13
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OPENTitle: Temporal Expression of Mutant LRRK2 in Adult Rats Impairs Dopamine ReuptakeJournal Name: International Journal of Biological SciencesPublisher: Ivyspring International PublisherVol: 7Issue #: 6Start Page: 753End Page: 761Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.7150/ijbs.7.753Best OA location URL: https://www.ijbs.com/v07p0753.pdfCitation Count: 57
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OPENTitle: Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging InitiativeJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 68Issue #: 1Start Page: 58End Page: 58Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2010.343Best OA location URL: https://europepmc.org/articles/pmc3259850?pdf=renderCitation Count: 146
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OPENTitle: Olfaction in Parkin heterozygotes and compound heterozygotesJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 4Start Page: 319End Page: 326Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820882aaBest OA location URL: https://europepmc.org/articles/pmc3034420?pdf=renderCitation Count: 48
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OPENTitle: Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degenerationJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 228Issue #: 1Start Page: 118End Page: 125Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.12.018Best OA location URL: https://europepmc.org/articles/pmc3041148?pdf=renderCitation Count: 72
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OPENTitle: A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusionsJournal Name: Molecular and Cellular NeurosciencePublisher: Elsevier BVVol: 46Issue #: 3Start Page: 597End Page: 606Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.mcn.2010.12.011Best OA location URL: https://europepmc.org/articles/pmc3046337?pdf=renderCitation Count: 71
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OPENTitle: Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoningJournal Name: Journal of General PhysiologyPublisher: Rockefeller University PressVol: 137Issue #: 1Start Page: 59End Page: 79Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1085/jgp.201010532Best OA location URL: https://rupress.org/jgp/article-pdf/137/1/59/1187438/jgp_201010532.pdfCitation Count: 160
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OPENTitle: TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriersJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 5Start Page: 467End Page: 474Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820a0e3bBest OA location URL: https://europepmc.org/articles/pmc3034409?pdf=renderCitation Count: 222
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OPENTitle: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S miceJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 41Issue #: 3Start Page: 706End Page: 716Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2010.12.008Best OA location URL: https://europepmc.org/articles/pmc3059106?pdf=renderCitation Count: 182
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RESTRICTEDTitle: Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implicationsJournal Name: Trends in NeurosciencesPublisher: Elsevier BVVol: 33Issue #: 12Start Page: 541End Page: 549Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.tins.2010.09.001Best OA location URL: https://europepmc.org/articles/pmc2981680?pdf=renderCitation Count: 190
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RESTRICTEDTitle: Molecular Chaperones as Rational Drug Targets for Parkinsons Disease TherapeuticsJournal Name: CNS & Neurological Disorders - Drug TargetsPublisher: Bentham Science Publishers Ltd.Vol: 9Issue #: 6Start Page: 741End Page: 753Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.2174/187152710793237386Best OA location URL: https://europepmc.org/articles/pmc3364514?pdf=renderCitation Count: 93
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OPENTitle: N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouseJournal Name: Annals of NeurologyPublisher: WileyVol: 69Issue #: 3Start Page: 509End Page: 520Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22162Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22162Citation Count: 125
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OPENTitle: Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brainsJournal Name: Movement DisordersPublisher: WileyVol: 26Issue #: 1Start Page: 27End Page: 36Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23442Best OA location URL: https://europepmc.org/articles/pmc6333467?pdf=renderCitation Count: 155
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OPENTitle: HCN channelopathy in external globus pallidus neurons in models of Parkinson's diseaseJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 14Issue #: 1Start Page: 85End Page: 92Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nn.2692Best OA location URL: https://europepmc.org/articles/pmc3058391?pdf=renderCitation Count: 180
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OPENTitle: Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: Time course of protection and neurorestorationJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1370Issue #:Start Page: 80End Page: 88Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.brainres.2010.11.006Best OA location URL: https://europepmc.org/articles/pmc3019295?pdf=renderCitation Count: 41
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OPENTitle: SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein LevelJournal Name: Archives of NeurologyPublisher: American Medical Association (AMA)Vol: 67Issue #: 11Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/archneurol.2010.279Best OA location URL: https://europepmc.org/articles/pmc3010848?pdf=renderCitation Count: 162
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OPENTitle: Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progressionJournal Name: Annals of NeurologyPublisher: WileyVol: 69Issue #: 3Start Page: 570End Page: 580Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22311Best OA location URL: https://europepmc.org/articles/pmc3117674?pdf=renderCitation Count: 394
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RESTRICTEDTitle: Chaperone-mediated autophagy: machinery, regulation and biological consequencesJournal Name: Cellular and Molecular Life SciencesPublisher: Springer Science and Business Media LLCVol: 68Issue #: 5Start Page: 749End Page: 763Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s00018-010-0565-6Citation Count: 111
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OPENTitle: Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 16Issue #: 10Start Page: 686End Page: 687Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2010.09.007Best OA location URL: https://europepmc.org/articles/pmc4381965?pdf=renderCitation Count: 38
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OPENTitle: CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s diseaseJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 118Issue #: 1Start Page: 23End Page: 26Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00702-010-0485-5Best OA location URL: https://europepmc.org/articles/pmc3090073?pdf=renderCitation Count: 13
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OPENTitle: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?Journal Name: Rambam Maimonides Medical JournalPublisher: Rambam Health CorporationVol: 1Issue #: 2Start Page: e0011End Page: e0011Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.5041/rmmj.10011Best OA location URL: https://www.rmmj.org.il/userimages/13/0/PublishFiles/13Article.pdfCitation Count: 8
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RESTRICTEDTitle: PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 2Issue #: 52Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3001059Best OA location URL: https://europepmc.org/articles/pmc3129986?pdf=renderCitation Count: 709