7651 - 7700 of 8808 Results
Title
Year
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OPENTitle: RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursorsJournal Name: Journal of Cell BiologyPublisher: Rockefeller University PressVol: 223Issue #: 6Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1083/jcb.202307092Best OA location URL: https://rupress.org/jcb/article-pdf/223/6/e202307092/1926155/jcb_202307092.pdfCitation Count: 14
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OPENTitle: Structure–Functional–Selectivity Relationship Studies of Novel Apomorphine Analogs to Develop D1R/D2R Biased LigandsJournal Name: ACS Medicinal Chemistry LettersPublisher: American Chemical Society (ACS)Vol: 11Issue #: 3Start Page: 385End Page: 392Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acsmedchemlett.9b00575Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7074212Citation Count: 12
- Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons2018OPENTitle: Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine NeuronsJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 103Issue #: 6Start Page: 874End Page: 892Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.ajhg.2018.10.018Best OA location URL: http://www.cell.com/article/S0002929718303707/pdfCitation Count: 39
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OPENTitle: Structural basis for the specificity of PPM1H phosphatase for Rab GTPasesJournal Name: EMBO reportsPublisher: Springer Science and Business Media LLCVol: 22Issue #: 11Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.15252/embr.202152675Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.202152675Citation Count: 20
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OPENTitle: CSF α-synuclein seed amplification kinetic profiles are associated with cognitive decline in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-023-00627-5Best OA location URL: https://www.nature.com/articles/s41531-023-00627-5.pdfCitation Count: 38
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OPENTitle: Increased iron-deposition in lateral-ventral substantia nigra pars compacta: A promising neuroimaging marker for Parkinson's diseaseJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 28Issue #:Start Page: 102391End Page: 102391Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2020.102391Best OA location URL: https://doi.org/10.1016/j.nicl.2020.102391Citation Count: 35
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OPENTitle: Gray Matter Volume Loss in Proposed Brain‐First and Body‐First Parkinson's Disease SubtypesJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 10Start Page: 2066End Page: 2074Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.29172Best OA location URL: https://doi.org/10.1002/mds.29172Citation Count: 26
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OPENTitle: The digital signature of emergent tremor in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/s41531-024-00754-7Best OA location URL: https://doi.org/10.1038/s41531-024-00754-7Citation Count: 4
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OPENTitle: Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility, and composition in striatum with cell-type and subunit specificityJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 121Issue #: 28Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1073/pnas.2317833121Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.2317833121Citation Count: 3
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OPENTitle: PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity terminationJournal Name: Journal of Cell BiologyPublisher: Rockefeller University PressVol: 217Issue #: 6Start Page: 2167End Page: 2184Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-saDOI - Digital Object Identifier: 10.1083/jcb.201708053Best OA location URL: https://rupress.org/jcb/article-pdf/217/6/2167/1067112/jcb_201708053.pdfCitation Count: 72
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OPENTitle: A unifying model for the role of the ATG8 system in autophagyJournal Name: Journal of Cell SciencePublisher: The Company of BiologistsVol: 135Issue #: 11Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1242/jcs.258997Best OA location URL: https://doi.org/10.1242/jcs.258997Citation Count: 23
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OPENTitle: The angiotensin (1–7) glycopeptide PNA5 improves cognition in a chronic progressive mouse model of Parkinson's disease through modulation of neuroinflammationJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 381Issue #:Start Page: 114926End Page: 114926Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.expneurol.2024.114926Citation Count: 5
- Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain2024OPENTitle: Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brainJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-024-00830-yBest OA location URL: https://doi.org/10.1038/s41531-024-00830-yCitation Count: 2
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OPENTitle: Increased yield of full GBA sequencing in Ashkenazi Jews with Parkinson's diseaseJournal Name: European Journal of Medical GeneticsPublisher: Elsevier BVVol: 62Issue #: 1Start Page: 65End Page: 69Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.ejmg.2018.05.005Citation Count: 61
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OPENTitle: Systems-level neurophysiological state characteristics for drug evaluation in an animal model of levodopa-induced dyskinesiaJournal Name: Journal of NeurophysiologyPublisher: American Physiological SocietyVol: 115Issue #: 3Start Page: 1713End Page: 1729Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1152/jn.00868.2015Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4809970Citation Count: 24
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OPENTitle: The LRRK2 kinase substrates RAB8a and RAB10 contribute complementary but distinct disease-relevant phenotypes in human neuronsJournal Name: Stem Cell ReportsPublisher: Elsevier BVVol: 19Issue #: 2Start Page: 163End Page: 173Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.stemcr.2024.01.001Best OA location URL: http://www.cell.com/article/S2213671124000043/pdfCitation Count: 8
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OPENTitle: Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian DisordersJournal Name: Journal of Neuroimmune PharmacologyPublisher: Springer Science and Business Media LLCVol: 14Issue #: 3Start Page: 423End Page: 435Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s11481-019-09835-4Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6669119Citation Count: 84
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OPENTitle: Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinaseJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 475Issue #: 1Start Page: 1End Page: 22Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bcj20170802Best OA location URL: https://portlandpress.com/biochemj/article-pdf/475/1/1/694077/bcj-2017-0802.pdfCitation Count: 150
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RESTRICTEDTitle: Generation of human midbrain organoids from induced pluripotent stem cellsJournal Name: MNI Open ResearchPublisher: F1000 Research LtdVol: 3Issue #:Start Page: 1End Page: 1Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.12688/mniopenres.12816.2Best OA location URL: https://doi.org/10.12688/mniopenres.12816.2Citation Count: 12
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OPENTitle: Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 9Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-023-00482-4Best OA location URL: https://www.nature.com/articles/s41531-023-00482-4.pdfCitation Count: 19
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OPENTitle: Gender Differences in the Prevalence of Parkinson's DiseaseJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 10Issue #: 1Start Page: 86End Page: 93Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mdc3.13584Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13584Citation Count: 48
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RESTRICTEDTitle: RNA sequencing of whole blood reveals early alterations in immune cells and gene expression in Parkinson’s diseaseJournal Name: Nature AgingPublisher: Springer Science and Business Media LLCVol: 1Issue #: 8Start Page: 734End Page: 747Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1038/s43587-021-00088-6Citation Count: 62
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OPENTitle: Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosaJournal Name: Movement DisordersPublisher: WileyVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.70123Best OA location URL: https://doi.org/10.1002/mds.70123Citation Count: 0
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OPENTitle: Predictors of cognitive impairment in primary age-related tauopathy: an autopsy studyJournal Name: Acta Neuropathologica CommunicationsPublisher: Springer Science and Business Media LLCVol: 9Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40478-021-01233-3Best OA location URL: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-021-01233-3Citation Count: 56
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OPENTitle: Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein SpreadingJournal Name: Advanced SciencePublisher: WileyVol: 12Issue #: 25Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/advs.202413052Best OA location URL: https://doi.org/10.1002/advs.202413052Citation Count: 0
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OPENTitle: Peripheral immune cell abundance differences link blood mitochondrial DNA copy number and Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-024-00831-xBest OA location URL: https://www.nature.com/articles/s41531-024-00831-x.pdfCitation Count: 3
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OPENTitle: Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's diseaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 120Issue #:Start Page: 107End Page: 117Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2018.09.004Best OA location URL: https://doaj.org/article/2232316968e3403b8d7208ad3725eaf1Citation Count: 125
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OPENTitle: Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargoJournal Name: Nature BiotechnologyPublisher: Springer Science and Business Media LLCVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41587-025-02565-4Best OA location URL: https://www.nature.com/articles/s41587-025-02565-4.pdfCitation Count: 7
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OPENTitle: Pathological α-syn aggregation is mediated by glycosphingolipid chain length and the physiological state of α-syn in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 118Issue #: 50Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.2108489118Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8685670Citation Count: 35
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OPENTitle: Serotonergic and dopaminergic control of impulsivity in gambling disorderJournal Name: Addiction BiologyPublisher: WileyVol: 28Issue #: 2Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1111/adb.13264Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/adb.13264Citation Count: 11
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OPENTitle: Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonistsJournal Name: British Journal of PharmacologyPublisher: WileyVol: 175Issue #: 5Start Page: 782End Page: 796Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/bph.14123Best OA location URL: https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bph.14123Citation Count: 20
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RESTRICTEDTitle: Effect of selective LRRK2 kinase inhibition on nonhuman primate lungJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 7Issue #: 273Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.aaa3634Citation Count: 338
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RESTRICTEDTitle: A pilot study of human brain tissue post-magnetic resonance imaging: Information from the National Deep Brain Stimulation Brain Tissue Network (DBS-BTN)Journal Name: NeuroImagePublisher: Elsevier BVVol: 54Issue #:Start Page: S233End Page: S237Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neuroimage.2010.09.014Citation Count: 9
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OPENTitle: Prevalence of impaired odor identification in Parkinson disease with imaging evidence of nigrostriatal denervationJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 123Issue #: 4Start Page: 421End Page: 424Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00702-016-1524-7Best OA location URL: http://doi.org/10.1007/s00702-016-1524-7Citation Count: 28
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OPENTitle: Orientation selective deep brain stimulationJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 14Issue #: 1Start Page: 016016End Page: 016016Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1088/1741-2552/aa5238Best OA location URL: http://doi.org/10.1088/1741-2552/aa5238Citation Count: 48
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OPENTitle: echolocatoR : an automated end-to-end statistical and functional genomic fine-mapping pipelineJournal Name: BioinformaticsPublisher: Oxford University Press (OUP)Vol: 38Issue #: 2Start Page: 536End Page: 539Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/bioinformatics/btab658Best OA location URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10060715/pdf/btab658.pdfCitation Count: 27
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OPENTitle: Resilience of striatal synaptic plasticity over early structural adaptations in premotor parkinsonismJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/s41531-025-00994-1Best OA location URL: https://www.nature.com/articles/s41531-025-00994-1.pdfCitation Count: 0
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OPENTitle: Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease PatientsJournal Name: Angewandte ChemiePublisher: WileyVol: 133Issue #: 21Start Page: 11981End Page: 11990Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/ange.202014898Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ange.202014898Citation Count: 23
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OPENTitle: Accelerating Medicines Partnership: Parkinson's Disease. Genetic ResourceJournal Name: Movement DisordersPublisher: WileyVol: 36Issue #: 8Start Page: 1795End Page: 1804Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.28549Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28549Citation Count: 98
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OPENTitle: Longitudinal in vivo metabolic labeling reveals tissue-specific mitochondrial proteome turnover rates and proteins selectively altered by parkin deficiencyJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-023-38484-0Best OA location URL: https://www.nature.com/articles/s41598-023-38484-0.pdfCitation Count: 7
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OPENTitle: Seeding activity of skin misfolded tau as a biomarker for tauopathiesJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 19Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-024-00781-1Best OA location URL: https://doi.org/10.1186/s13024-024-00781-1Citation Count: 5
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RESTRICTEDTitle: Biallelic NUDT2 variants defective in mRNA decapping cause a neurodevelopmental diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 147Issue #: 4Start Page: 1197End Page: 1205Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1093/brain/awad434Best OA location URL: https://hal.science/hal-05121495Citation Count: 7
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OPENTitle: Common and rare variants in HFE are not associated with Parkinson's disease in EuropeansJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 107Issue #:Start Page: 174End Page: 177Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2021.05.019Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8595489Citation Count: 2
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OPENTitle: HFE H63D Limits Nigral Vulnerability to Paraquat in Agricultural WorkersJournal Name: Toxicological SciencesPublisher: Oxford University Press (OUP)Vol: 181Issue #: 1Start Page: 47End Page: 57Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/toxsci/kfab020Best OA location URL: https://academic.oup.com/toxsci/article-pdf/181/1/47/37464453/kfab020.pdfCitation Count: 6
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OPENTitle: RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer’s diseaseJournal Name: Nucleic Acids ResearchPublisher: Oxford University Press (OUP)Vol: 52Issue #: 18Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/nar/gkae776Best OA location URL: https://doi.org/10.1093/nar/gkae776Citation Count: 2
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OPENTitle: Using global team science to identify genetic parkinson's disease worldwideJournal Name: Annals of NeurologyPublisher: WileyVol: 86Issue #: 2Start Page: 153End Page: 157Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25514Best OA location URL: http://hdl.handle.net/10072/416166Citation Count: 33
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OPENTitle: Phenotypical variability in the 6-OHDA mouse model of Parkinson's disease despite consistent and robust nigral lesioningJournal Name: Brain MechanismsPublisher: Elsevier BVVol: 148-150Issue #:Start Page: 202523End Page: 202523Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bramec.2025.202523Best OA location URL: https://doi.org/10.1016/j.bramec.2025.202523Citation Count: 0
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OPENTitle: Human pegivirus alters brain and blood immune and transcriptomic profiles of patients with Parkinson’s diseaseJournal Name: JCI InsightPublisher: American Society for Clinical InvestigationVol: 10Issue #: 13Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1172/jci.insight.189988Best OA location URL: https://doi.org/10.1172/jci.insight.189988Citation Count: 0
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OPENTitle: Fine-mapping of Parkinson’s disease susceptibility loci identifies putative causal variantsJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 31Issue #: 6Start Page: 888End Page: 900Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/hmg/ddab294Best OA location URL: https://academic.oup.com/hmg/article-pdf/31/6/888/42993647/ddab294.pdfCitation Count: 36
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RESTRICTEDTitle: Singing in groups for Parkinson's disease (SING-PD): A pilot study of group singing therapy for PD-related voice/speech disordersJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 18Issue #: 5Start Page: 548End Page: 552Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2012.02.009Citation Count: 66