1401 - 1450 of 8673 Results
Title
Year
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OPENTitle: Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studiesJournal Name: Molecular BrainPublisher: Springer Science and Business Media LLCVol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1756-6606-1-16Best OA location URL: https://molecularbrain.biomedcentral.com/counter/pdf/10.1186/1756-6606-1-16Citation Count: 23
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OPENTitle: Clinimetric testing of the comprehensive cervical dystonia rating scaleJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 4Start Page: 563End Page: 569Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26534Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4833533Citation Count: 46
- A randomized, double-blind study of repeated incobotulinumtoxinA (Xeomin®) in cervical dystonia2013OPENTitle: A randomized, double-blind study of repeated incobotulinumtoxinA (Xeomin®) in cervical dystoniaJournal Name: Journal of Neural TransmissionPublisher: Springer Science and Business Media LLCVol: 120Issue #: 12Start Page: 1699End Page: 1707Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00702-013-1048-3Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00702-013-1048-3.pdfCitation Count: 66
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OPENTitle: Rapid Generation of Functional Dopaminergic Neurons From Human Induced Pluripotent Stem Cells Through a Single-Step Procedure Using Cell Lineage Transcription FactorsJournal Name: Stem Cells Translational MedicinePublisher: Oxford University Press (OUP)Vol: 2Issue #: 6Start Page: 473End Page: 479Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.5966/sctm.2012-0133Best OA location URL: https://doi.org/10.5966/sctm.2012-0133Citation Count: 90
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OPENTitle: Multiple system atrophy is not caused by C9orf72 hexanucleotide repeat expansionsJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 36Issue #: 2Start Page: 1223.e1End Page: 1223.e2Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2014.08.033Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4315721Citation Count: 30
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OPENTitle: Comparative Transduction Efficiency of AAV Vector Serotypes 1–6 in the Substantia Nigra and Striatum of the Primate BrainJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 18Issue #: 3Start Page: 588End Page: 593Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2009.286Best OA location URL: http://www.cell.com/article/S1525001616323085/pdfCitation Count: 127
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OPENTitle: Fusion to a highly charged proteasomal retargeting sequence increases soluble cytoplasmic expression and efficacy of diverse anti-synuclein intrabodiesJournal Name: mAbsPublisher: Informa UK LimitedVol: 4Issue #: 6Start Page: 686End Page: 693Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.4161/mabs.21696Best OA location URL: https://www.tandfonline.com/doi/pdf/10.4161/mabs.21696?needAccess=trueCitation Count: 68
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OPENTitle: Reduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriersJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 141Issue #: 2Start Page: 486End Page: 495Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/awx344Best OA location URL: https://academic.oup.com/brain/article-pdf/141/2/486/24175904/awx344.pdfCitation Count: 44
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OPENTitle: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 7Start Page: 2626End Page: 2631Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1318306111Best OA location URL: https://www.pnas.org/content/pnas/111/7/2626.full.pdfCitation Count: 350
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OPENTitle: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathologyJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 22Issue #: 1Start Page: 47End Page: 56Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7Citation Count: 217
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OPENTitle: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric diseaseJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 21Issue #: 10Start Page: 1482End Page: 1492Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41593-018-0223-0Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6334654Citation Count: 95
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OPENTitle: Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population‐based elderly cohortJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 12Issue #: 12Start Page: 1226End Page: 1234Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jalz.2016.06.001Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5148697Citation Count: 127
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OPENTitle: Age-specific penetrance ofLRRK2G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 ConsortiumJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 85Issue #: 1Start Page: 89End Page: 95Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001708Best OA location URL: https://n.neurology.org/content/neurology/85/1/89.full.pdfCitation Count: 158
- Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix Compartments2011OPENTitle: Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix CompartmentsJournal Name: Frontiers in NeuroanatomyPublisher: Frontiers Media SAVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnana.2011.00059Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnana.2011.00059/pdfCitation Count: 411
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OPENTitle: The Penn Parkinson's Daily Activities Questionnaire-15: Psychometric properties of a brief assessment of cognitive instrumental activities of daily living in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 25Issue #:Start Page: 21End Page: 26Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.02.020Best OA location URL: http://doi.org/10.1016/j.parkreldis.2016.02.020Citation Count: 56
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OPENTitle: Whole-Exome Sequencing in Familial Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 73Issue #: 1Start Page: 68End Page: 68Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2015.3266Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2470417/noi150080.pdfCitation Count: 75
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OPENTitle: Spatiotemporal Pattern of Striatal ERK1/2 Phosphorylation in a Rat Model of L-DOPA–Induced Dyskinesia and the Role of Dopamine D1 ReceptorsJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 62Issue #: 7Start Page: 800End Page: 810Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2006.11.032Best OA location URL: http://doi.org/10.1016/j.biopsych.2006.11.032Citation Count: 272
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OPENTitle: Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010Journal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 71Issue #: 4Start Page: 266End Page: 273Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0b013e31824b211bBest OA location URL: https://academic.oup.com/jnen/article-pdf/71/4/266/9561527/71-4-266.pdfCitation Count: 989
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OPENTitle: A soluble α-synuclein construct forms a dynamic tetramerJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 43Start Page: 17797End Page: 17802Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1113260108Citation Count: 445
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OPENTitle: O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's diseaseJournal Name: Nature ChemistryPublisher: Springer Science and Business Media LLCVol: 7Issue #: 11Start Page: 913End Page: 920Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nchem.2361Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4618406Citation Count: 253
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OPENTitle: Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and ModelingJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 123Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/55609Citation Count: 38
- Molecular tweezers for lysine and arginine – powerful inhibitors of pathologic protein aggregation2016OPENTitle: Molecular tweezers for lysine and arginine – powerful inhibitors of pathologic protein aggregationJournal Name: Chemical CommunicationsPublisher: Royal Society of Chemistry (RSC)Vol: 52Issue #: 76Start Page: 11318End Page: 11334Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1039/c6cc04640aBest OA location URL: https://doi.org/10.1039/c6cc04640aCitation Count: 127
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OPENTitle: Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation studyJournal Name: PLOS MedicinePublisher: Public Library of Science (PLoS)Vol: 14Issue #: 6Start Page: e1002314End Page: e1002314Publication Date:Open Access(OA) Status: OPENLicense: cc0DOI - Digital Object Identifier: 10.1371/journal.pmed.1002314Best OA location URL: https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1002314&type=printableCitation Count: 178
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OPENTitle: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 107Issue #: 21Start Page: 9879End Page: 9884Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1004676107Best OA location URL: http://doi.org/10.1073/pnas.1004676107Citation Count: 491
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OPENTitle: Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian RatsJournal Name: Stem CellsPublisher: Oxford University Press (OUP)Vol: 26Issue #: 1Start Page: 55End Page: 63Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1634/stemcells.2007-0494Best OA location URL: https://academic.oup.com/stmcls/article-pdf/26/1/55/41941319/stmcls_26_1_55.pdfCitation Count: 279
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OPENTitle: In vivo demonstration that α-synuclein oligomers are toxicJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 10Start Page: 4194End Page: 4199Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1100976108Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976Citation Count: 1395
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OPENTitle: Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson’s disease subjectsJournal Name: Neurological ResearchPublisher: Informa UK LimitedVol: 34Issue #: 7Start Page: 669End Page: 676Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1179/1743132812y.0000000063Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3681206Citation Count: 65
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OPENTitle: Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatumJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 19Issue #: 4Start Page: 578End Page: 586Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nn.4252Citation Count: 157
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OPENTitle: LRRK2 secretion in exosomes is regulated by 14-3-3Journal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 22Issue #: 24Start Page: 4988End Page: 5000Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddt346Best OA location URL: https://academic.oup.com/hmg/article-pdf/22/24/4988/14140078/ddt346.pdfCitation Count: 161
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OPENTitle: Vesicular dysfunction and pathways to neurodegenerationJournal Name: Essays in BiochemistryPublisher: Portland Press Ltd.Vol: 65Issue #: 7Start Page: 941End Page: 948Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1042/ebc20210034Best OA location URL: https://portlandpress.com/essaysbiochem/article-pdf/65/7/941/929366/ebc-2021-0034c.pdfCitation Count: 7
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OPENTitle: In situ architecture of neuronal α-Synuclein inclusionsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 12Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41467-021-22108-0Best OA location URL: https://www.nature.com/articles/s41467-021-22108-0.pdfCitation Count: 103
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OPENTitle: Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signaturesJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41531-022-00282-2Best OA location URL: https://escholarship.org/uc/item/1jb2z7qrCitation Count: 36
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OPENTitle: In situ structural analysis reveals membrane shape transitions during autophagosome formationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 119Issue #: 39Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1073/pnas.2209823119Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9522377Citation Count: 79
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OPENTitle: Highly efficient generation of isogenic pluripotent stem cell models using prime editingJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 11Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.79208Best OA location URL: https://doi.org/10.7554/elife.79208Citation Count: 48
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OPENTitle: From structure to ætiology: a new window on the biology of leucine-rich repeat kinase 2 and Parkinson's diseaseJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 478Issue #: 14Start Page: 2945End Page: 2951Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1042/bcj20210383Best OA location URL: https://portlandpress.com/biochemj/article-pdf/478/14/2945/918073/bcj-2021-0383.pdfCitation Count: 5
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OPENTitle: Molecular markers of early Parkinson's disease based on gene expression in bloodJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 3Start Page: 955End Page: 960Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0610204104Best OA location URL: http://doi.org/10.1073/pnas.0610204104Citation Count: 502
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OPENTitle: Alzheimer brain-derived tau oligomers propagate pathology from endogenous tauJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 2Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-saDOI - Digital Object Identifier: 10.1038/srep00700Best OA location URL: https://doi.org/10.1038/srep00700Citation Count: 465
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OPENTitle: Prevalence of Parkinson’s disease across North AmericaJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-018-0058-0Best OA location URL: https://escholarship.org/uc/item/1qs1g07mCitation Count: 883
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OPENTitle: Factors Influencing the Measurement of Lysosomal Enzymes Activity in Human Cerebrospinal FluidJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 7Start Page: e101453End Page: e101453Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0101453Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0101453&type=printableCitation Count: 25
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 41Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: http://europepmc.org/articles/PMC3799334Citation Count: 176
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OPENTitle: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseasesJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/sdata.2016.89Best OA location URL: https://doi.org/10.1038/sdata.2016.89Citation Count: 427
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OPENTitle: Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathwayJournal Name: HippocampusPublisher: WileyVol: 27Issue #: 7Start Page: 784End Page: 793Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/hipo.22731Citation Count: 22
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OPENTitle: n-3 PUFA supplementation benefits microglial responses to myelin pathologyJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-saDOI - Digital Object Identifier: 10.1038/srep07458Best OA location URL: https://doi.org/10.1038/srep07458Citation Count: 130
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OPENTitle: Caffeine and risk of Parkinson's disease in a large cohort of men and womenJournal Name: Movement DisordersPublisher: WileyVol: 27Issue #: 10Start Page: 1276End Page: 1282Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25076Citation Count: 184
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OPENTitle: CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashionJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 78Issue #: 10Start Page: 690End Page: 695Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e318249f683Best OA location URL: https://hdl.handle.net/2108/99911Citation Count: 346
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OPENTitle: Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s diseaseJournal Name: NeurosciencePublisher: Elsevier BVVol: 258Issue #:Start Page: 385End Page: 400Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuroscience.2013.11.038Citation Count: 51
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OPENTitle: Behavioral Characterization of A53T Mice Reveals Early and Late Stage Deficits Related to Parkinson’s DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 8Start Page: e70274End Page: e70274Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0070274Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0070274&type=printableCitation Count: 178
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OPENTitle: Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammationJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 215Issue #: 1Start Page: 5End Page: 19Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2008.09.003Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2765462Citation Count: 240
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OPENTitle: The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactionsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-017-05760-9Best OA location URL: https://www.nature.com/articles/s41598-017-05760-9.pdfCitation Count: 64
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OPENTitle: Imaging of microglia in patients with neurodegenerative disordersJournal Name: Frontiers in PharmacologyPublisher: Frontiers Media SAVol: 3Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fphar.2012.00096Best OA location URL: https://kclpure.kcl.ac.uk/portal/en/publications/389ab5ad-f662-40b8-981e-c6f04a287c58Citation Count: 112