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MJFF Publications

3101 - 3150 of 9140 Results
Title
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  • 2019
  • Summary Details
    RESTRICTED
    Title: Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau181, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease
    Journal Name: JAMA Neurology
    Publisher: American Medical Association (AMA)
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1001/jamaneurol.2013.3861
    Citation Count: 368
  • Summary Details
    OPEN
    Title: Directed Brain Connectivity Identifies Widespread Functional Network Abnormalities in Parkinson’s Disease
    Journal Name: Cerebral Cortex
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/cercor/bhab237
    Citation Count: 21
  • Summary Details
    OPEN
    Title: Early and Accurate Diagnosis of Parkinson Disease May Be Rooted in Seed Amplification Assays
    Journal Name: Clinical Chemistry
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/clinchem/hvad111
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Deep learning for clustering of multivariate clinical patient trajectories with missing values
    Journal Name: GigaScience
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1093/gigascience/giz134
    Citation Count: 71
  • Summary Details
    OPEN
    Title: Identification of LRRK2 missense variants in the accelerating medicines partnership Parkinson’s disease cohort
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddab058
    Citation Count: 36
  • Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson’s disease patient fibroblasts
    2019
    Summary Details
    RESTRICTED
    Title: Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson’s disease patient fibroblasts
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/ddz126
    Citation Count: 66
  • Summary Details
    OPEN
    Title: HFE H63D Limits Nigral Vulnerability to Paraquat in Agricultural Workers
    Journal Name: Toxicological Sciences
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/toxsci/kfab020
    Citation Count: 7
  • Concerns with the new biological research criteria for synucleinopathy – Authors' reply
    2024
    Summary Details
    RESTRICTED
    Title: Concerns with the new biological research criteria for synucleinopathy – Authors' reply
    Journal Name: The Lancet Neurology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/s1474-4422(24)00233-3
    Citation Count: 5
  • Summary Details
    OPEN
    Title: Diabetes mellitus is independently associated with more severe cognitive impairment in Parkinson disease
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.10.008
    Citation Count: 111
  • Summary Details
    OPEN
    Title: Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.nbd.2019.104525
    Citation Count: 108
  • Disease-modifying therapies for Parkinson's disease
    2013
    Summary Details
    OPEN
    Title: Disease-modifying therapies for Parkinson's disease
    Journal Name: The Biomedical & Life Sciences Collection
    Publisher: Henry Stewart Talks
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.69645/krxj9755
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Colonic inflammation in Parkinson's disease
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2012.09.007
    Citation Count: 642
  • Summary Details
    RESTRICTED
    Title: EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.03.004
    Citation Count: 17
  • Summary Details
    OPEN
    Title: Differentially expressed genes in Alzheimer’s disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1
    Journal Name: Brain, Behavior, & Immunity - Health
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.bbih.2021.100227
    Citation Count: 72
  • Summary Details
    OPEN
    Title: Capturing Differences in the Regulation of LRRK2 Dynamics and Conformational States by Small Molecule Kinase Inhibitors
    Journal Name: ACS Chemical Biology
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1021/acschembio.2c00868
    Citation Count: 20
  • Summary Details
    OPEN
    Title: Lasker~Bloomberg Public Service Award to Michael J. Fox: The challenge of Parkinson’s disease
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: National Academy of Sciences
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1073/pnas.2622460123
    Citation Count: 0
  • The Progressive Supranuclear Palsy Clinical Deficits Scale accurately reflects functional as well as patient- and caregiver-reported outcomes
    2025
    Summary Details
    RESTRICTED
    Title: The Progressive Supranuclear Palsy Clinical Deficits Scale accurately reflects functional as well as patient- and caregiver-reported outcomes
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2025.108060
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing
    Journal Name: Genome Biology
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1186/s13059-017-1147-9
    Citation Count: 124
  • Summary Details
    OPEN
    Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.celrep.2017.12.066
    Citation Count: 715
  • Summary Details
    OPEN
    Title: Reply: Growth differentiation factor 5 exerts neuroprotection in an α-synuclein rat model of Parkinson’s disease and BMP5/7 protect dopaminergic neurons in an α-synuclein mouse model of Parkinson’s disease
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/awaa369
    Citation Count: 1
  • Summary Details
    OPEN
    Title: Skin α-synuclein seed amplification assay for the identification of multiple system atrophy
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41531-026-01565-8
    Citation Count: 0
  • PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology
    2018
    Summary Details
    RESTRICTED
    Title: PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27523
    Citation Count: 47
  • Summary Details
    OPEN
    Title: Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy
    Journal Name: Molecular Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13024-018-0245-9
    Citation Count: 75
  • Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: Four cases
    2011
    Summary Details
    RESTRICTED
    Title: Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: Four cases
    Journal Name: Journal of the Neurological Sciences
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.jns.2011.06.003
    Citation Count: 36
  • Summary Details
    OPEN
    Title: Chemogenomic Profiling of Endogenous PARK2 Expression Using a Genome-Edited Coincidence Reporter
    Journal Name: ACS Chemical Biology
    Publisher: American Chemical Society (ACS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/cb5010417
    Citation Count: 56
  • Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
    2010
    Summary Details
    RESTRICTED
    Title: Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.06.017
    Citation Count: 210
  • Summary Details
    OPEN
    Title: Gut Microbial Metabolites and Future Risk of Parkinson's Disease: A Metabolome‐Wide Association Study
    Journal Name: Movement Disorders
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mds.30054
    Citation Count: 11
  • Summary Details
    OPEN
    Title: Measuring Structural Racism: A Guide for Epidemiologists and Other Health Researchers
    Journal Name: American Journal of Epidemiology
    Publisher: Oxford University Press (OUP)
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/aje/kwab239
    Citation Count: 399
  • Summary Details
    OPEN
    Title: Evidence‐based standardized sample handling protocol for accurate blood‐based Alzheimer's disease biomarker measurement: Results and consensus of the Global Biomarker Standardization Consortium
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/alz.70752
    Citation Count: 22
  • Summary Details
    OPEN
    Title: A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.7554/elife.40202
    Citation Count: 274
  • Summary Details
    OPEN
    Title: Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson’s disease-like neurodegeneration
    Journal Name: Fluids and Barriers of the CNS
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12987-025-00646-9
    Citation Count: 9
  • Summary Details
    OPEN
    Title: O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease
    Journal Name: Molecular Brain
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13041-017-0311-1
    Citation Count: 95
  • Summary Details
    OPEN
    Title: Fox Insight: Most Bothersome Symptoms in Early‐Stage Parkinson's Disease
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mdc3.14321
    Citation Count: 7
  • Summary Details
    OPEN
    Title: Alterations in sleep-activity cycles and clock gene expression across the synucleinopathy spectrum
    Journal Name: Translational Neurodegeneration
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s40035-025-00492-7
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2024.05.017
    Citation Count: 14
  • Summary Details
    OPEN
    Title: Tau protein aggregation is associated with cellular senescence in the brain
    Journal Name: Aging Cell
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1111/acel.12840
    Citation Count: 591
  • Summary Details
    OPEN
    Title: Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum
    Journal Name: European Journal of Neuroscience
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ejn.13941
    Citation Count: 22
  • Summary Details
    OPEN
    Title: Foundations of circadian medicine
    Journal Name: PLOS Biology
    Publisher: Public Library of Science (PLoS)
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pbio.3001567
    Citation Count: 94
  • Summary Details
    OPEN
    Title: Mapping movement, mood, motivation and mentation in the subthalamic nucleus
    Journal Name: Royal Society Open Science
    Publisher: The Royal Society
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1098/rsos.171177
    Citation Count: 38
  • Summary Details
    OPEN
    Title: Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson's disease: a double-blind, randomised controlled trial
    Journal Name: The Lancet Neurology
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/s1474-4422(19)30285-6
    Citation Count: 579
  • Methamphetamine‐induced mitochondrial oxidant stress mediated by monoamine oxidase metabolism of dopamine
    2017
    Summary Details
    RESTRICTED
    Title: Methamphetamine‐induced mitochondrial oxidant stress mediated by monoamine oxidase metabolism of dopamine
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1096/fasebj.31.1_supplement.987.3
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Type 2 Diabetes Mellitus, Cognitive Performance, and Incident Dementia; Identifying Mediating Pathways and Biomarkers From the Plasma Proteome
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1111/jnc.70306
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Additive effect of distant Lewy bodies and tau seeds injections on nigral degeneration in macaques
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd, cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1038/s41531-025-00938-9
    Citation Count: 3
  • Summary Details
    OPEN
    Title: Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-017-0862-1
    Citation Count: 44
  • Summary Details
    OPEN
    Title: Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson’s disease: a genetic association study
    Journal Name: BMC Neurology
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12883-018-1023-6
    Citation Count: 18
  • Summary Details
    OPEN
    Title: Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2018.00036
    Citation Count: 101
  • Summary Details
    OPEN
    Title: Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-019-01993-2
    Citation Count: 94
  • Summary Details
    OPEN
    Title: Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease
    Journal Name: Cell Reports Medicine
    Publisher: Elsevier BV
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.xcrm.2025.101999
    Citation Count: 25
  • Summary Details
    OPEN
    Title: CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.70367
    Citation Count: 0
  • Summary Details
    OPEN
    Title: Different Circulating Trace Amine Profiles in De Novo and Treated Parkinson’s Disease Patients
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-019-42535-w
    Citation Count: 48
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