4001 - 4050 of 8785 Results
Title
Year
- Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease2018OPENTitle: Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's DiseaseJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 11Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2018.00454Best OA location URL: https://doi.org/10.3389/fnmol.2018.00454Citation Count: 69
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OPENTitle: DNAJC13 mutations in Parkinson diseaseJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 23Issue #: 7Start Page: 1794End Page: 1801Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddt570Best OA location URL: http://doi.org/10.1093/hmg/ddt570Citation Count: 302
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OPENTitle: Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cellsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ncomms1669Best OA location URL: https://www.nature.com/articles/ncomms1669.pdfCitation Count: 243
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 119
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OPENTitle: Neuron‐to‐neuron transmission of α‐synuclein fibrils through axonal transportJournal Name: Annals of NeurologyPublisher: WileyVol: 72Issue #: 4Start Page: 517End Page: 524Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.23747Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3490229Citation Count: 335
- Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism2016OPENTitle: Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropismJournal Name: Gene TherapyPublisher: Springer Science and Business Media LLCVol: 23Issue #: 11Start Page: 807End Page: 814Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/gt.2016.62Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5541369Citation Count: 78
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OPENTitle: Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort studyJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 12Issue #: 10Start Page: 978End Page: 988Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s1474-4422(13)70210-2Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3879782Citation Count: 261
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OPENTitle: Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact SystemsJournal Name: CellPublisher: Elsevier BVVol: 163Issue #: 6Start Page: 1500End Page: 1514Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.cell.2015.11.025Best OA location URL: http://www.cell.com/article/S0092867415015056/pdfCitation Count: 469
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OPENTitle: VPS35 Mutations in Parkinson DiseaseJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 89Issue #: 1Start Page: 162End Page: 167Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.ajhg.2011.06.001Best OA location URL: http://www.cell.com/article/S0002929711002424/pdfCitation Count: 847
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk2013OPENTitle: RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease RiskJournal Name: NeuronPublisher: Elsevier BVVol: 77Issue #: 3Start Page: 425End Page: 439Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.neuron.2012.11.033Best OA location URL: http://www.cell.com/article/S0896627312011208/pdfCitation Count: 511
- Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a2003OPENTitle: Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5aJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 100Issue #: 22Start Page: 12747End Page: 12752Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1534900100Best OA location URL: http://doi.org/10.1073/pnas.1534900100Citation Count: 359
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OPENTitle: Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutationsJournal Name: AutophagyPublisher: Informa UK LimitedVol: 15Issue #: 1Start Page: 113End Page: 130Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1080/15548627.2018.1509818Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15548627.2018.1509818?needAccess=trueCitation Count: 197
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OPENTitle: Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 4Issue #: 141Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3003985Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3462009Citation Count: 490
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OPENTitle: Extracellular vesicle sorting of α-Synuclein is regulated by sumoylationJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 129Issue #: 5Start Page: 695End Page: 713Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-015-1408-1Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-015-1408-1.pdfCitation Count: 158
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OPENTitle: Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's diseaseJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 16Issue #: 9Start Page: 998End Page: 1000Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nm.2199Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2935926Citation Count: 368
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OPENTitle: Solvent exposures and parkinson disease risk in twinsJournal Name: Annals of NeurologyPublisher: WileyVol: 71Issue #: 6Start Page: 776End Page: 784Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.22629Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22629Citation Count: 167
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OPENTitle: HCN channelopathy in external globus pallidus neurons in models of Parkinson's diseaseJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 14Issue #: 1Start Page: 85End Page: 92Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nn.2692Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3058391Citation Count: 184
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OPENTitle: Maladaptive striatal plasticity in l-DOPA-induced dyskinesiaJournal Name: Progress in Brain ResearchPublisher: ElsevierVol:Issue #:Start Page: 209End Page: 233Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s0079-6123(10)83011-0Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2930606Citation Count: 198
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OPENTitle: Derivation of midbrain dopamine neurons from human embryonic stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 101Issue #: 34Start Page: 12543End Page: 12548Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0404700101Best OA location URL: http://doi.org/10.1073/pnas.0404700101Citation Count: 984
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OPENTitle: Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTPJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 105Issue #: 5Start Page: 1716End Page: 1721Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0705363105Best OA location URL: http://doi.org/10.1073/pnas.0705363105Citation Count: 249
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OPENTitle: Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseasesJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 21Issue #: 15Start Page: 3500End Page: 3512Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/dds161Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3392107Citation Count: 226
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OPENTitle: Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseasesJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 38Issue #:Start Page: 214.e7End Page: 214.e10Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.10.028Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2015.10.028Citation Count: 87
- The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?2017OPENTitle: The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?Journal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-016-0002-0Best OA location URL: https://www.nature.com/articles/s41531-016-0002-0.pdfCitation Count: 475
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 116
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OPENTitle: The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseasesJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 109Issue #:Start Page: 226End Page: 248Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nbd.2016.12.013Best OA location URL: https://doi.org/10.1016/j.nbd.2016.12.013Citation Count: 238
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OPENTitle: Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 101Issue #: 50Start Page: 17510End Page: 17515Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0405313101Best OA location URL: http://doi.org/10.1073/pnas.0405313101Citation Count: 324
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OPENTitle: Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synucleinJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-018-35464-7Best OA location URL: https://www.nature.com/articles/s41598-018-35464-7.pdfCitation Count: 40
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OPENTitle: CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonismJournal Name: Journal of NeurochemistryPublisher: WileyVol: 95Issue #: 4Start Page: 974End Page: 986Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2005.03428.xCitation Count: 285
- β‐amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementia2012OPENTitle: β‐amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementiaJournal Name: Movement DisordersPublisher: WileyVol: 28Issue #: 3Start Page: 296End Page: 301Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25213Best OA location URL: https://hdl.handle.net/2027.42/97160Citation Count: 89
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OPENTitle: Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long termJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 135Issue #: 1Start Page: 65End Page: 83Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-017-1792-9Best OA location URL: https://link.springer.com/content/pdf/10.1007%2Fs00401-017-1792-9.pdfCitation Count: 184
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OPENTitle: Translation Initiator EIF4G1 Mutations in Familial Parkinson DiseaseJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 89Issue #: 3Start Page: 398End Page: 406Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.ajhg.2011.08.009Best OA location URL: http://www.cell.com/article/S0002929711003594/pdfCitation Count: 286
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OPENTitle: A Genome‐Wide Linkage Screen in the Amish with Parkinson Disease Points to Chromosome 6Journal Name: Annals of Human GeneticsPublisher: WileyVol: 75Issue #: 3Start Page: 351End Page: 358Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1469-1809.2011.00643.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1469-1809.2011.00643.xCitation Count: 10
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OPENTitle: Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative DiseasesJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 74Issue #: 9Start Page: 934End Page: 942Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0000000000000235Best OA location URL: https://academic.oup.com/jnen/article-pdf/74/9/934/8146595/74-9-934.pdfCitation Count: 13
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OPENTitle: Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort studyJournal Name: Journal of Translational MedicinePublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12967-017-1313-6Best OA location URL: https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-017-1313-6Citation Count: 27
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OPENTitle: Generation of Stable Transgenic C. elegans Using MicroinjectionJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 18Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/833Best OA location URL: https://www.jove.com/pdf/833/generation-of-stable-transgenic-c-elegans-using-microinjectionCitation Count: 84
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OPENTitle: Application of a C. elegans Dopamine Neuron Degeneration Assay for the Validation of Potential Parkinson's Disease GenesJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 17Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/835Best OA location URL: https://www.jove.com/pdf/835/application-c-elegans-dopamine-neuron-degeneration-assay-forCitation Count: 46
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OPENTitle: Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed inXenopus laevisoocytesJournal Name: The Journal of PhysiologyPublisher: WileyVol: 586Issue #: 1Start Page: 227End Page: 245Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1113/jphysiol.2007.143172Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2375544Citation Count: 97
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OPENTitle: Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP ExpressionJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 120Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/54981Best OA location URL: https://www.jove.com/pdf/54981/reliable-identification-living-dopaminergic-neurons-midbrain-culturesCitation Count: 7
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OPENTitle: Host and Microbial Factors in Regulation of T Cells in the IntestineJournal Name: Frontiers in ImmunologyPublisher: Frontiers Media SAVol: 4Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fimmu.2013.00141Best OA location URL: https://www.frontiersin.org/articles/10.3389/fimmu.2013.00141/pdfCitation Count: 18
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OPENTitle: Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive PhosphateJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 79Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/50523Best OA location URL: https://www.jove.com/pdf/50523/metabolic-labeling-leucine-rich-repeat-kinases-1-2-with-radioactiveCitation Count: 4
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OPENTitle: Detection of Protein UbiquitinationJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 30Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/1293Best OA location URL: https://www.jove.com/pdf/1293/detection-of-protein-ubiquitinationCitation Count: 95
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OPENTitle: Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free AssaysJournal Name: Journal of Visualized ExperimentsPublisher: MyJove CorporationVol:Issue #: 126Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3791/55361Citation Count: 7
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OPENTitle: Subject-specific computational modeling of DBS in the PPTg areaJournal Name: Frontiers in Computational NeurosciencePublisher: Frontiers Media SAVol: 9Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fncom.2015.00093Best OA location URL: https://doi.org/10.3389/fncom.2015.00093Citation Count: 10
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OPENTitle: Neurogenic dysphagia with undigested macaroni and megaesophagus in familial dysautonomiaJournal Name: Clinical Autonomic ResearchPublisher: Springer Science and Business Media LLCVol: 28Issue #: 1Start Page: 125End Page: 126Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s10286-017-0487-6Citation Count: 12
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OPENTitle: MAPT haplotype diversity in multiple system atrophyJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 30Issue #:Start Page: 40End Page: 45Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.06.010Best OA location URL: http://doi.org/10.1016/j.parkreldis.2016.06.010Citation Count: 27
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OPENTitle: Lewy bodies in essential tremor are no different than in controlsJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 23Issue #:Start Page: 106End Page: 107Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.11.025Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5683710Citation Count: 7
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OPENTitle: Pantothenate kinase‐associated neurodegeneration is not a synucleinopathyJournal Name: Neuropathology and Applied NeurobiologyPublisher: WileyVol: 39Issue #: 2Start Page: 121End Page: 131Publication Date:Open Access(OA) Status: OPENLicense: unspecified-oaDOI - Digital Object Identifier: 10.1111/j.1365-2990.2012.01269.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2990.2012.01269.xCitation Count: 52
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OPENTitle: Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signalingJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep14125Best OA location URL: https://www.nature.com/articles/srep14125.pdfCitation Count: 38
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OPENTitle: Long-term Transgene Expression in the Central Nervous System Using DNA NanoparticlesJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 17Issue #: 4Start Page: 641End Page: 650Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2009.2Best OA location URL: https://doi.org/10.1038/mt.2009.2Citation Count: 77
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OPENTitle: Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tauJournal Name: NeuropsychopharmacologyPublisher: Springer Science and Business Media LLCVol: 44Issue #: 1Start Page: 222End Page: 223Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41386-018-0204-8Best OA location URL: https://www.nature.com/articles/s41386-018-0204-8.pdfCitation Count: 1