4501 - 4550 of 8587 Results
Title
Year
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OPENTitle: Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule bindingJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 479Issue #: 17Start Page: 1759End Page: 1783Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1042/bcj20220161Best OA location URL: https://portlandpress.com/biochemj/article-pdf/479/17/1759/936843/bcj-2022-0161.pdfCitation Count: 93
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OPENTitle: Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) DimerizationJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 14Issue #: 11Start Page: 1971End Page: 1980Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1021/acschemneuro.3c00259Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.3c00259Citation Count: 17
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OPENTitle: Loss of parkin causes endoplasmic reticulum calcium dyshomeostasis by upregulation of reticulocalbin 1Journal Name: European Journal of NeurosciencePublisher: WileyVol: 57Issue #: 5Start Page: 739End Page: 761Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1111/ejn.15917Citation Count: 2
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OPENTitle: Structure-based design and characterization of Parkin-activating mutationsJournal Name: Life Science AlliancePublisher: Life Science Alliance, LLCVol: 6Issue #: 6Start Page: e202201419End Page: e202201419Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.26508/lsa.202201419Best OA location URL: https://www.life-science-alliance.org/content/lsa/6/6/e202201419.full.pdfCitation Count: 23
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OPENTitle: Sex differences in the diagnosis latency of Parkinson's disease in Latin AmericaJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 134Issue #:Start Page: 107344End Page: 107344Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.parkreldis.2025.107344Best OA location URL: https://doi.org/10.1016/j.parkreldis.2025.107344Citation Count: 0
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OPENTitle: Reference SVA insertion polymorphisms are associated with Parkinson’s Disease progression and differential gene expressionJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-021-00189-4Best OA location URL: https://www.nature.com/articles/s41531-021-00189-4.pdfCitation Count: 45
- Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases2016OPENTitle: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPasesJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.12813Best OA location URL: https://cdn.elifesciences.org/articles/12813/elife-12813-v2.pdfCitation Count: 925
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RESTRICTEDTitle: Dopamine-mediated improvements in dynamic balance control in Parkinson’s diseaseJournal Name: Gait & PosturePublisher: Elsevier BVVol: 82Issue #:Start Page: 68End Page: 74Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.gaitpost.2020.08.132Citation Count: 9
- Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans2024OPENTitle: Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in transJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 13Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.96699Best OA location URL: https://cdn.elifesciences.org/articles/96699/elife-96699-v1.pdfCitation Count: 1
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OPENTitle: [11C]JNJ54173717, a novel P2X7 receptor radioligand as marker for neuroinflammation: human biodistribution, dosimetry, brain kinetic modelling and quantification of brain P2X7 receptors in patients with Parkinson’s disease and healthy volunteersJournal Name: European Journal of Nuclear Medicine and Molecular ImagingPublisher: Springer Science and Business Media LLCVol: 46Issue #: 10Start Page: 2051End Page: 2064Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00259-019-04369-6Best OA location URL: https://lirias.kuleuven.be/bitstream/123456789/649475/3/Article_P2X7radioligand.pdfCitation Count: 68
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OPENTitle: Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal CellsJournal Name: Oxidative Medicine and Cellular LongevityPublisher: WileyVol: 2019Issue #:Start Page: 1End Page: 11Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2019/4246350Best OA location URL: https://downloads.hindawi.com/journals/omcl/2019/4246350.pdfCitation Count: 31
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OPENTitle: Neurosurgeons perspective on the shift towards earlier use of deep brain stimulation for Parkinson diseaseJournal Name: Interdisciplinary NeurosurgeryPublisher: Elsevier BVVol: 25Issue #:Start Page: 101224End Page: 101224Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.inat.2021.101224Best OA location URL: https://doi.org/10.1016/j.inat.2021.101224Citation Count: 2
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RESTRICTEDTitle: Inflammatory profile discriminates clinical subtypes in LRRK2‐associated Parkinson's diseaseJournal Name: European Journal of NeurologyPublisher: WileyVol: 24Issue #: 2Start Page: 427End Page: 427Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/ene.13223Citation Count: 54
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OPENTitle: Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screeningJournal Name: Chemical SciencePublisher: Royal Society of Chemistry (RSC)Vol: 11Issue #: 47Start Page: 12746End Page: 12754Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1039/d0sc02159hBest OA location URL: https://pubs.rsc.org/en/content/articlepdf/2020/sc/d0sc02159hCitation Count: 42
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OPENTitle: Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brainsJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 309Issue #:Start Page: 91End Page: 106Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2018.07.016Citation Count: 46
- Comprehensive Analysis of Familial Parkinsonism Genes in Rapid‐Eye‐Movement Sleep Behavior Disorder2020OPENTitle: Comprehensive Analysis of Familial Parkinsonism Genes in Rapid‐Eye‐Movement Sleep Behavior DisorderJournal Name: Movement DisordersPublisher: WileyVol: 36Issue #: 1Start Page: 235End Page: 240Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.28318Best OA location URL: http://hdl.handle.net/11380/1227849Citation Count: 13
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OPENTitle: Genetic Architecture of Parkinson's Disease in the Indian Population: Harnessing Genetic Diversity to Address Critical Gaps in Parkinson's Disease ResearchJournal Name: Frontiers in NeurologyPublisher: Frontiers Media SAVol: 11Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fneur.2020.00524Best OA location URL: https://doi.org/10.3389/fneur.2020.00524Citation Count: 35
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OPENTitle: Levodopa Versus Dopamine Agonist after Subthalamic Stimulation in Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 36Issue #: 3Start Page: 672End Page: 680Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.28382Best OA location URL: https://onlinelibrary.wiley.com/doi/pdf/10.1002/mds.28382Citation Count: 20
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OPENTitle: Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factorJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 7Issue #: 24Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.abg6677Best OA location URL: https://www.science.org/doi/pdf/10.1126/sciadv.abg6677Citation Count: 45
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RESTRICTEDTitle: An interpretable deep learning Bayesian optimized random forest framework for the diagnosis of Parkinson's disease in structural magnetic resonance imagesJournal Name: International Journal of Imaging Systems and TechnologyPublisher: WileyVol: 34Issue #: 4Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/ima.23106Citation Count: 0
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RESTRICTEDTitle: Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug StrategyJournal Name: ACS Chemical NeurosciencePublisher: American Chemical Society (ACS)Vol: 9Issue #: 11Start Page: 2542End Page: 2547Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00236Citation Count: 12
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OPENTitle: NEAT1 is overexpressed in Parkinson's disease substantia nigra and confers drug‐inducible neuroprotection from oxidative stressJournal Name: The FASEB JournalPublisher: WileyVol: 33Issue #: 10Start Page: 11223End Page: 11234Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1096/fj.201900830rBest OA location URL: https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201900830RCitation Count: 90
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OPENTitle: echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipelineJournal Name: BioinformaticsPublisher: Oxford University Press (OUP)Vol: 38Issue #: 2Start Page: 536End Page: 539Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/bioinformatics/btab658Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10060715Citation Count: 27
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RESTRICTEDTitle: Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease: A longitudinal 123I-FP-CIT SPECT studyJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 77Issue #:Start Page: 170End Page: 175Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.03.025Citation Count: 38
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OPENTitle: Pharmacological targeting of dopamine D1 or D2 receptors evokes a rapid‐onset parkinsonian motor phenotype in miceJournal Name: European Journal of NeurosciencePublisher: WileyVol: 60Issue #: 12Start Page: 7006End Page: 7024Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1111/ejn.16622Best OA location URL: https://onlinelibrary.wiley.com/doi/pdf/10.1111/ejn.16622Citation Count: 3
- Impact of oral COMT-inhibitors on gut microbiota and short chain fatty acids in Parkinson's disease2019RESTRICTEDTitle: Impact of oral COMT-inhibitors on gut microbiota and short chain fatty acids in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 70Issue #:Start Page: 20End Page: 22Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.11.020Citation Count: 16
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OPENTitle: Is Levodopa Response a Valid Indicator of Parkinson's Disease?Journal Name: Movement DisordersPublisher: WileyVol: 36Issue #: 4Start Page: 948End Page: 954Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.28406Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8046721Citation Count: 35
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OPENTitle: Cerebellar resting-state functional connectivity in Parkinson's disease and multiple system atrophy: Characterization of abnormalities and potential for differential diagnosis at the single-patient levelJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 22Issue #:Start Page: 101720End Page: 101720Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2019.101720Best OA location URL: https://doi.org/10.1016/j.nicl.2019.101720Citation Count: 46
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OPENTitle: Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and CognitionJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 75Issue #: 8Start Page: 748End Page: 754Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/jnen/nlw047Best OA location URL: https://academic.oup.com/jnen/article-pdf/75/8/748/33451979/nlw047.pdfCitation Count: 122
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OPENTitle: NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathyJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 117Issue #: 3Start Page: 1762End Page: 1771Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1909110117Best OA location URL: https://www.pnas.org/content/pnas/117/3/1762.full.pdfCitation Count: 112
- Parkinson's disease-related network topographies characterized with resting state functional MRI2016OPENTitle: Parkinson's disease-related network topographies characterized with resting state functional MRIJournal Name: Human Brain MappingPublisher: WileyVol: 38Issue #: 2Start Page: 617End Page: 630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/hbm.23260Best OA location URL: http://doi.org/10.1002/hbm.23260Citation Count: 71
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OPENTitle: Alpha‐Synuclein Oligomers and Neurofilament Light Chain in Spinal Fluid Differentiate Multiple System Atrophy from Lewy Body SynucleinopathiesJournal Name: Annals of NeurologyPublisher: WileyVol: 88Issue #: 3Start Page: 503End Page: 512Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25824Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7719613Citation Count: 109
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OPENTitle: Tremor in Spinocerebellar Ataxia Type 12Journal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 1Issue #: 1Start Page: 76End Page: 78Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12015Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12015Citation Count: 9
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RESTRICTEDTitle: Reply to: “Could Blood Hexosylsphingosine Be a Marker for Parkinson's Disease Linked with GBA1 Mutations”?Journal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 8Start Page: 1782End Page: 1782Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.29136Citation Count: 0
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RESTRICTEDTitle: Exosome/microvesicle content is altered in leucine‐rich repeat kinase 2 mutant induced pluripotent stem cell‐derived neural cellsJournal Name: Journal of Comparative NeurologyPublisher: WileyVol: 528Issue #: 7Start Page: 1203End Page: 1215Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/cne.24819Citation Count: 14
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RESTRICTEDTitle: The KV7.2/3 preferring channel opener ICA 27243 attenuates L-DOPA-induced dyskinesia in hemiparkinsonian ratsJournal Name: Neuroscience LettersPublisher: Elsevier BVVol: 545Issue #:Start Page: 59End Page: 63Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neulet.2013.04.017Citation Count: 7
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OPENTitle: Central and peripheral α‐synuclein in Parkinson disease detected by seed amplification assayJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 10Issue #: 5Start Page: 696End Page: 705Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/acn3.51753Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.51753Citation Count: 26
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OPENTitle: OnabotulinumtoxinA and cognitive behavioral therapy in functional dystonia: A pilot randomized clinical trialJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 63Issue #:Start Page: 174End Page: 178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.02.009Best OA location URL: https://zenodo.org/record/3832127Citation Count: 17
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OPENTitle: Multiple N-of-1 trials to investigate hypoxia therapy in Parkinson’s disease: study rationale and protocolJournal Name: BMC NeurologyPublisher: Springer Science and Business Media LLCVol: 22Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12883-022-02770-7Best OA location URL: https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/s12883-022-02770-7Citation Count: 10
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OPENTitle: Color discrimination errors associate with axial motor impairments in Parkinson's DiseaseJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 4Issue #: 6Start Page: 864End Page: 869Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12527Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.12527Citation Count: 7
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RESTRICTEDTitle: Multimodal Blood-Based Biomarker Panel Reveals Altered Lysosomal Ionic Content in Alzheimer’s DiseaseJournal Name: ACS Chemical BiologyPublisher: American Chemical Society (ACS)Vol: 20Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/acschembio.4c00602Citation Count: 1
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RESTRICTEDTitle: Transcriptome-wide Association Study in Frontotemporal Dementia Identifies New Disease Loci by In Silico AnalysisJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 89Issue #: 8Start Page: e37End Page: e39Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2021.02.010Citation Count: 0
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OPENTitle: Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 lociJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 145Issue #: 12Start Page: 4349End Page: 4367Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1093/brain/awac325Best OA location URL: https://academic.oup.com/brain/article-pdf/145/12/4349/48181830/awac325.pdfCitation Count: 52
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RESTRICTEDTitle: Loss of glutamic acid decarboxylase (Gad67) in striatal neurons expressing the Drdr1a dopamine receptor prevents l-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned miceJournal Name: NeurosciencePublisher: Elsevier BVVol: 303Issue #:Start Page: 586End Page: 594Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neuroscience.2015.07.032Citation Count: 17
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OPENTitle: Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and ToxicityJournal Name: ACS Chemical BiologyPublisher: American Chemical Society (ACS)Vol: 11Issue #: 4Start Page: 931End Page: 942Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acschembio.5b01042Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6300141Citation Count: 31
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OPENTitle: Traumatic brain injury in the prodromal period of Parkinson's disease: A large epidemiological study using medicare dataJournal Name: Annals of NeurologyPublisher: WileyVol: 82Issue #: 5Start Page: 744End Page: 754Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.25074Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5812286Citation Count: 45
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OPENTitle: Composite measures of motor performance and self-efficacy are better determinants of postural instability and gait difficulties than individual clinical measures in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 107Issue #:Start Page: 105251End Page: 105251Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1016/j.parkreldis.2022.105251Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10028594Citation Count: 4
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OPENTitle: Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9Journal Name: Gene TherapyPublisher: Springer Science and Business Media LLCVol: 29Issue #: 6Start Page: 390End Page: 397Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41434-021-00244-yBest OA location URL: https://www.nature.com/articles/s41434-021-00244-y.pdfCitation Count: 31
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OPENTitle: Role of LRRK2 in the regulation of dopamine receptor traffickingJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 12Issue #: 6Start Page: e0179082End Page: e0179082Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0179082Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179082&type=printableCitation Count: 67