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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2014
    Improving Gait in Parkinson’s Disease Patients by Non-invasive Electrical Stimulation of the Cerebellum

    Study Rationale:
    People with Parkinson’s disease (PD) can experience difficulties walking (e.g., freezing), which can lead to falls and negatively impact quality of life. These symptoms are difficult...

  • Improved Neuromodulation Approaches, 2014
    Adaptive Closed Loop Neuromodulation and Neural Signatures of Parkinson’s Disease

    Study Rationale:
    Currently deep brain stimulation (DBS) is limited to “open-loop” stimulation, without real-time adjustment to the patient’s state of activity, fluctuations and types of motor symptoms...

  • Rapid Response Innovation Awards, 2014
    Creating Dopaminergic Neurons in the Adult Brain

    Study Rationale:
    Loss of dopaminergic neurons is seen in Parkinson’s disease, and transplantation of these neurons can greatly ease symptoms. However, several major drawbacks are associated with...

  • Rapid Response Innovation Awards, 2014
    Effect of Dietary Ketosis On Alpha-Synuclein Accumulation

    Study Rationale:
    A key feature of Parkinson’s disease is abnormal accumulation of the protein alpha-synuclein. Production of organic compounds called ketones is a normal metabolic process that occurs...

  • Rapid Response Innovation Awards, 2014
    D-512: a Novel, Multifunctional D2/D3 Receptor Agonist for the Treatment of Parkinson’s Disease

    Study Rationale:                   
    New drugs for the treatment of Parkinson’s disease (PD) that reduce symptoms and protect remaining neurons are desperately needed. This work examines a novel...

  • Rapid Response Innovation Awards, 2014
    Levodopa Versus Dopamine Agonist after Deep Brain Stimulation in Parkinson's Disease

    Study Rationale:                   
    Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for patients with advanced Parkinson's disease (PD). STN DBS improves motor...

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