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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2013
    Developing Disease-Modifying Therapies to Treat Parkinsons’s Disease by Enhancing the Clearance of Alpha Synuclein

    Objective/Rationale:
    This proposal seeks to develop a novel therapy that can slow the progression of Parkinson’s disease (PD) by optimizing chemical compounds that can decrease levels of alpha...

  • Research Grant, 2013
    Continuous Subcutaneous Administration of Levodopa/Carbidopa (ND0612) for the Treatment of Parkinson's Disease

    Objective/Rationale:             
    Improving consistency of plasma levodopa has been a longstanding pharmacological challenge. ND0612 is a proprietary formulation of levodopa and carbidopa continuously...

  • MJFF Research Grant, 2013
    Delivery of GDNF to the Brain by Novel Nanovesicles for the Treatment of Parkinson’s Disease (Supplement)

    Promising Outcomes of Original Grant:
    The overall goal of this project is to develop V-SmartTM nanovesicles for delivering GDNF to the brain as a novel treatment of Parkinson's disease (PD). In the...

  • MJFF Research Grant, 2013
    A Study to Evaluate Feasibility, Safety and Preliminary Efficacy of Magnetic Resonance Image Guided Focused Ultrasound for the Treatment of Parkinson’s Disease Dyskinesia

    Objective/Rationale:             
    The effectiveness of drug therapy to alleviate Parkinson’s disease (PD) symptoms often diminishes over time, and side effects such as dyskinesia (involuntary...

  • MJFF Research Grant, 2013
    Transcutaneous Submandibular Gland Biopsy: A Diagnostic Test for Early Parkinson’s Disease

    Objective/Rationale:             
    We have previously found that in autopsied patients with Parkinson’s disease (PD) the hallmark finding in the brain (Lewy-type alpha synuclein staining or LTS) is...

  • Rapid Response Innovation Awards, 2013
    Neuromelanin in Circulating Phagocytes May Reveal Early Neurodegeneration in Parkinson’s Disease

    Objective/Rationale:             
    A normal function of inflammation is to recruit phagocytic white blood cells (think PACMAN) to clear away the damaged cells. We postulate that debris laden PACMEN re...

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