The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2016Electrical Stimulation of the Brain as Parkinson's Disease Treatment
Study Rationale:
Depression is a common non-motor symptom associated with Parkinson's disease (PD), and impulse control disorders (ICDs) are behaviors that may arise with use of certain PD medications... -
Research Grant, 2016Registry for the Advancement of Deep Brain Stimulation Therapy in Parkinson's Disease (RAD-PD)
Study Rationale:
Deep brain stimulation (DBS) is a surgical treatment for Parkinson's disease (PD) that may benefit those who experience motor complications, such as "off" periods and/or dyskinesia... -
Access to Data and Biospecimens, 2016MicroRNAs as biomarkers of the prodromal stage of Parkinson disease’
Study Rationale:
MicroRNAs (miRNAs) are small regulatory RNAs controlling gene expression. We have recently reported reduced miRNAs levels in serum from Parkinson disease (PD) patients, and also from...
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Research Grant, 2016Study of Alpha-synuclein in the Dorsal Neostriatum
Promising Outcomes of Original Grant:
In February 2013, Luk et al. published in Science that administration of synthetic alpha-synuclein into pre-formed fibrils in pre-clinical models was sufficient to... -
Therapeutic Pipeline Program, 2016Effect of HDAC Inhibition in Models of Parkinson's Disease
Study Rationale:
Numerous publications have linked the family of epigenetic enzymes known as HDACs (histone deactylases) to the underlying pathology of Parkinson's. This study will test the efficacy of... -
Therapeutic Pipeline Program, 2016Cognitive Behavioral Therapy for Anxiety Disorders in Parkinson's Disease
Study Rationale:
Anxiety disorders occur in up to 35 percent of people with Parkinson's disease and can have a negative impact on gait, involuntary movements, motor fluctuations and quality of life...
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Our funding programs support basic, translational and clinical research from academia and industry.