The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Aligning Science Across Parkinson's, 2020Role of PD-related Proteins as Drivers of Disease through Modulation of Innate and Adaptive Immunity
Study Rationale:
The hallmark motor impairments in Parkinson’s disease patients are due to the progressive loss of a special type of neuron in the brain using the chemical messenger dopamine. The... -
Aligning Science Across Parkinson's, 2020Tracing the Origin and Progression of Parkinson’s Disease through the Neuro-immune Interactome
Study Rationale:
While inflammation of the brain caused by immune cells has been implicated in Parkinson’s disease (PD), it is unknown whether these cells attacking the brain initiate the disease... -
Aligning Science Across Parkinson's, 2020Mechanisms Overwhelming Protein and Organelle Quality Control in Parkinson’s Disease
Study Rationale:
Abnormal protein aggregation and prion-like aggregate spreading are hallmarks of the degenerative cascades of sporadic and familial Parkinson’s disease (PD) and can damage cells... -
Aligning Science Across Parkinson's, 2020In Vivo Approach to Elucidate the Pathobiology of Parkinson’s-associated Genes Using Human Diseased Neurons
Study Rationale:
Several genes are known to be associated with Parkinson’s disease, although how they impact the disease process is not fully understood. Here we will use stem cells from patients in... -
Aligning Science Across Parkinson's, 2020Senescence in Parkinson’s Disease and Related Disorders
Study Rationale:
While aging is the greatest risk factor for development of Parkinson’s disease (PD), how aging promotes PD is not fully understood. Examining the role of cellular senescence... -
Aligning Science Across Parkinson's, 2020Mechanisms of Mitochondrial Damage Control by PINK1 and Parkin
Study Rationale:
Mitochondria are tiny power-generating stations within all cells, including neurons. They are vital energy producers, but when things go wrong, they can spew toxic materials and...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.