The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Filter Results (18)
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Non-pharmacological Interventions for Gait and Balance, 2019Use of a Robotic Walking Device to Improve Home and Community Mobility in People with Parkinson's Disease
Study Rationale:
People with Parkinson's disease can have walking issues that prevent them from completing daily activities in and outside of their homes. This study uses a light, wearable robotic... -
GBA Biology and Therapies, 2018GBA Defects Cause C5a-C5aR1-induced Neurodegeneration in Parkinson’s Disease
Study Rationale:
People with GBA-associated Parkinson’s disease (PD) lack enzymes that break down certain fatty molecules (e.g., glucosylceramide), preventing their cells from shedding these waste... -
Target Advancement Program, 2017Farnesoid X Receptor to Reduce Neuroinflammation
Study Rationale:
Although the precise mechanism(s) for neurodegeneration in Parkinson's disease (PD) is unknown, evidence suggests that neuroinflammation is an important contributor. In this study, we... -
Target Advancement Program, 2016Farnesoid X Receptor as a Target to Reduce Meuroinflammation
Study Rationale:
Although the precise mechanism(s) of neurodegeneration in Parkinson's disease (PD) are unknown, evidence suggests that neuroinflammation is an important contributor. In this study, we... -
Target Advancement Program, 2016Targeting the Mitochondrial Unfolded Protein Response in Alpha-synuclein-induced Parkinson's Disease
Study Rationale:
The mitochondrial (powerhouse of the cell) unfolded protein response (mtUPR) is the first defense mechanism for maintaining proper quality of proteins within the mitochondria. Defects... -
Rapid Response Innovation Awards, 2014Effect of Dietary Ketosis On Alpha-Synuclein Accumulation
Study Rationale:
A key feature of Parkinson’s disease is abnormal accumulation of the protein alpha-synuclein. Production of organic compounds called ketones is a normal metabolic process that occurs...
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Our funding programs support basic, translational and clinical research from academia and industry.