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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2020
    California Parkinson’s Disease Registry

    Study Rationale:    
    This project will support operations and enhancement of the California Parkinson’s Disease Registry (CPDR) for one year. CPDR captures and stores information on all Parkinson’s...

  • Research Grant, 2020
    Biomarker for Mitophagy Pathway Activation

    Study Rationale:    
    Abnormal PINK1-PRKN directed mitochondrial quality control appears to be an important contributor to Parkinson’s disease (PD). Measures to assess activation of this pathway in...

  • Research Grant Supplement, 2020
    Developing Biosignatures for Parkinson's Disease Using Sense of Smell (Supplement)

    Study Rationale:
    It has been described that people with Parkinson’s disease have a specific signature odor. This odor arises from an oily skin secretion called sebum. Odor detection in the nose is...

  • Priority Biology, 2021
    Developing New Therapeutic Drugs for Parkinson’s in Human Stem Cell Neurons

    Study Rationale:
    Neurons derived from stem cells from people with Parkinson’s disease offer an opportunity to perform drug and target discovery. We completed a screen of 4,000 drug compounds in such...

  • Research Grant, 2020
    Studying the Effects of TMEM175 and CTSB on Glucocerebrosidase Activity and Alpha-synuclein Properties

    Promising Outcomes of Original Grant:
    The aim of the original grant was to study if there are genes that modify the risk of Parkinson’s disease (PD) or the age at onset of PD, among people who carry...

  • Priority Biology, 2020
    Effects of LRRK2 Variants on GCase Activity in iPSC-derived Dopamine Neurons and Microglia

    Study Rationale:
    There is contradictory evidence on whether the LRRK2 and GBA genes, and the proteins that they encode, interact in their effects on Parkinson’s disease. Some studies suggest that...

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Our funding programs support basic, translational and clinical research from academia and industry.

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