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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Aligning Science Across Parkinson's, 2021
    Basal Ganglia Networks in Parkinson's Disease
    ASAP logo

    Study Rationale:
    People with Parkinson's disease have long been known to display remarkable motor abilities under special circumstances such as smooth walking with certain visual or auditory cues...

  • Aligning Science Across Parkinson's, 2021
    Distributed Circuit Dysfunction Underlying Motor and Sleep Deficits in a Progressive Model of Parkinson’s Disease
    ASAP logo

    Study Rationale:
    Parkinson’s disease (PD) begins decades before it compromises the ability to move about in the world and sleep through the night. Understanding how the dysfunction of brain circuits...

  • Aligning Science Across Parkinson's, 2021
    Activity and Connectivity Drive Neuronal Vulnerability and Disease Progression in Parkinson’s Disease
    ASAP logo

    Study Rationale:
    Specific brain circuits that are highly melanized (build-up of the dark pigment neuromelanin) with age are primarily affected, particularly early, in Parkinson's disease. Models...

  • Aligning Science Across Parkinson's, 2021
    Cortical Pathophysiology of Parkinsonism
    ASAP logo

    Study Rationale:
    The outer mantle of the brain, the cerebral cortex, plays a significant role in selecting and controlling movements. Changes in the activity of cortical neurons are key to disorders...

  • Fall 2021 RFP: Expanding Biological Understanding of PD, 2021
    Using Human iPSC to Explore the Role of the STING Pathway in Parkinson's Disease

    Study Rationale: Inflammation is recognized as a factor in the progression of Parkinson’s disease (PD). The PD-associated genes PINK1 and Parkin are involved in eliminating damaged cell components...

  • Fall 2021 RFP: Outcome Measures, 2021
    Use of Image-enhancement Techniques to Assess Anatomical Changes in Parkinson’s Disease

    Study Rationale: Parkinson’s disease (PD) has several subtypes. Identification of these subtypes in individuals with PD is important for understanding disease progression, developing new therapies...

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