Funded Studies

The project will use multipotent neural stem cells as starting material. These cells, which reside in the central nervous system, will be isolated from the developing brains of five- to eight-week-old...

We have recently succeeded in differentiating adult human and animal bone marrow stromal stem cells (BMSCs) into neurons (nerve cells). A subpopulation of the neurons activates functions that are...

There is growing evidence that certain areas of the adult central nervous system retain the capacity to generate new neurons from endogenous immature progenitor cells. Our preliminary results show...

We intend to develop lines of clonal, stable and self-renewing human dopamine-producing neuronal progenitor cells. These will be derived from the part of the midbrain that gives rise to dopamine...

Study Rationale: Proteasomes are cylinder-like structures inside cells that breakdown unnecessary or damaged proteins. When proteasomes do not work properly, the unwanted proteins may accumulate and...

Study Rationale: Parkinson’s disease is often diagnosed using tests that require spinal fluid, which is collected through an invasive procedure called a lumbar puncture. However, this method can be...