The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2007Potential Utility of Novel CNS-active Experimental Therapeutics for Parkinson's Disease
Objective/Rationale:
Evidence suggests that overproduction of inflammatory molecules, called proinflammatory cytokines, from glial cells in the brain can contribute to nerve cell death and accelerate... -
Rapid Response Innovation Awards, 2007Neuroprotective effects of isradipine in a pre-clinical model of Parkinson’s disease
Objective/Rationale:
Recent work by our group has shown that blocking L-type Ca2+ channels protects vulnerable dopaminergic neurons in three animal models Parkinson’s disease (PD). Isradipine, a high... -
Rapid Response Innovation Awards, 2007Genetic characterization of Omi/Htra2 (PARK13) in autosomal dominant and sporadic Parkinson’s disease
Objective/Rationale:
Identification of DNA variations that cause familial/sporadic parkinsonism has provided insight into the biological pathways involved in disease. Thirteen loci (PARK1-13) have... -
Target Validation, 2007Development of Lentiviral DN-TNF Vectors: A Novel Anti-inflammatory Gene Therapy to Block Nigrostriatal Degeneration
Objective/Rationale:
A growing number of epidemiological and experimental animal studies implicate neuroinflammatory mechanisms in the progressive death of midbrain dopamine (DA) neurons in Parkinson’s...
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Clinical Intervention Awards, 2007Serotonin and Sleep Disordered Breathing in Parkinson Disease
Objective/Rationale:
Sleep related problems are a major cause of impairment in Parkinson's disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing... -
Clinical Intervention Awards, 2007The PARKFIT Study: Effectiveness of an Active Lifestyle Promotion Program for Patients with Parkinson’s disease
Objective/Rationale:
Parkinson's patients are inclined toward a sedentary lifestyle. This is due to a combination of both physical handicaps (e.g. walking difficulties) and mential impairments (e.g...
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Our funding programs support basic, translational and clinical research from academia and industry.