The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2025Scamps: Endosomal Membrane Proteins that Control Alpha-synuclein Traffic
Study Rationale: Parkinson’s Disease progresses with the death of nerve cells in the brain. Some forms of the disease run in families due to mutations in important genes. One of these genes is called...
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Research Grant, 2025Analysis of 18F-DPA714 Dynamic Data with Arterial Sampling Obtained at UAB
Study Rationale: The study will analyze clinical PET data from 5 subjects imaged dynamically with 18F-DPA714, an imaging larker for brain inflammation. The purpose of the study is to ensure that...
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Research Grant, 2025Analysis of a Potential Alpha-synuclein PET Tracer (18F-FD4) in HC, PD and MSA
Study Rationale: 18F-FD4 is a new imaging agent that has the potential to image alpha-synuclein in the living human brain with Positron Emission Tomography (PET). Given alpha-synuclein’s central role...
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Circuits & Cellular Targets for PD’s Symptoms, 2025Role of B2*-Nicotinic Receptors in Parkinson’s Disease Related Circuits and Symptoms
Study Rationale: One pathological hallmark of Parkinson’s disease (PD) is the degeneration of dopamine neurons innervating the striatum. Dopamine loss is associated with several adaptive changes in...
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MRI Biomarkers Program, 2025Molecular MRI Correlates of Parkinsonian Neurodegeneration
Study Rationale: New imaging tools for Parkinson’s disease (PD) are urgently needed to help accelerate the development of new treatments. A special type of MRI scan, CEST MRI, can detect changes in...
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MRI Biomarkers Program, 2025Validate Diffusion MRI Biomarkers of Early PD: A Multi-cohort Study of Free-water and CDM Measure
Study Rationale: Parkinson’s disease and related synucleinopathies, such as Dementia with Lewy Bodies, are challenging to diagnose at their earliest stages due to subtle initial symptoms. Our research...
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Our funding programs support basic, translational and clinical research from academia and industry.