The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2011Blood-Brain Barrier Modification Using Heterotopic Nasal Mucosal Grafting for Enhanced Symptoms & Side Effects and Macromolecular Disease Modifying Drug Delivery in Parkinson's Disease
Objective/Rationale:
One of the most significant problems in the treatment of Parkinson’s disease is the inability to provide continuous and high molecular weight drug delivery to the central nervous... -
LEAPS, 2011Supplement to 'Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD'
Promising Outcomes of Original Grant:
Activation or potentiation of metabotropic glutamate receptor 4 (mGluR4) is a promising new strategy for both Symptoms & Side Effects and disease-modifying... -
Rapid Response Innovation Awards, 2011A New Strategy to Ameliorate Chemically-induced Parkinson-like Symptoms by Engaging the Spinal Locomotor Circuitry with Epidural Stimulation
Objective/Rationale:
Our objective is to determine if we can change the level of excitability of the spinal cord circuitry that controls posture and locomotion so that the sensory information derived... -
MJFF Research Grant, 2011Generation of Alpha-synuclein Filament Protein and Characterization of Alpha-synuclein Rabbit Monoclonal Antibodies
Objective/Rationale:
Aggregation of alpha-synuclein plays a pivotal role in the development of Parkinson’s disease. This subproject focuses on supporting the MJFF initiative of generating monoclonal... -
Research Grant, 2011Effect of Novel Neuronal Nicotinic Receptor Compounds on Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease
Promising Outcomes of Original Grant:
The aim of the original grant was to identify compounds specifically targeting one or more neuronal nicotinic receptors (NNRs) in the central nervous system for... -
MJFF Research Grant, 2011In Vivo Validation of the AAV-alpha-synuclein Vectors Generated by UNC for Distribution to MJFF Supported Research Community
Objective/Rationale:
The Michael J. Fox Foundation would like to generate those tools and reagents that can be of greatest use to PD researchers. Working with Dr. R. Jude Samulski at The University...
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Our funding programs support basic, translational and clinical research from academia and industry.