The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Novel PET Tracer Development Program, 2023Development of a PET Tracer for Imaging of Neuroinflammation in Parkinson’s Disease
Study Rationale: Neuroinflammation plays a key role in the degeneration of dopamine-producing neurons and is critical in the pathogenesis of Parkinson’s disease (PD). Positron Emission Tomography (PET...
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Biomarkers to Support Therapeutic Trials Program, 2023Blood Test for Stratifying People with Parkinson’s Disease based on Extracellular Vesicles Derived from Neurons
Study Rationale: Parkinson’s disease (PD) and other synucleinopathies are diagnosed based on symptoms and clinical testing. However, these tests can be inaccurate, and postmortem analysis reveals that...
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Spring 2022 RFP: Proof-of-Concept Testing of PD Therapeutics, 2022Preclinical Models and Therapies for the Gastrointestinal Symptoms of Parkinson’s Disease
Study Rationale: In addition to the well-recognized movement abnormalities associated with Parkinson’s disease (PD), gastrointestinal symptoms such as constipation, leaky gut and inflammation are also...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Inhibiting Programmed Cell Death to Reduce Axonal Degeneration and Brain Inflammation in Parkinson's Disease
Study Rationale: The degeneration of neuronal axons is an early pathological feature of Parkinson’s disease (PD) and an attractive target for therapeutic intervention. We have demonstrated that a...
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Research Grant, 2022Establishing a Parkinson’s Disease Registry in West Virginia
Study Rationale: The state of West Virginia has one of the nation’s highest rates of Parkinson’s disease (PD), a condition for which the causes are not well understood and there is no cure. In April...
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Translational Pipeline Program, 2023Inhibiting Faulty DNA Repair as a Strategy for Preventing Neuronal Loss in Parkinson’s Disease
Study Rationale: Cells have mechanisms for repairing damaged DNA. Unfortunately, these repair mechanisms can themselves become inefficient and error-prone as we age — leading to the accumulation of...
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Our funding programs support basic, translational and clinical research from academia and industry.