The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2024Developing A Resource for Exploring the Molecular Markers of Parkinson’s Disease
Study Rationale: Our understanding of the genetic, immunological and molecular determinants of Parkinson’s disease (PD) has advanced significantly over the past decade. Using this extensive body of...
-
Research Grant, 2024(SUPPLEMENT) Cataloguing Proteomic Differences in LRRK2-Associated Parkinsonism With and Without Evidence of Pathologic Neuronal Alpha-synuclein
Study Rationale: Alpha-synuclein is a protein found throughout the brain and body. In most people with Parkinson’s disease (PD), an accumulation of abnormal alpha-synuclein is thought to contribute to...
-
Data-Driven Subtyping and Stratification Program, 2023Longitudinal Investigation of Statistical Subtype Analysis in Genetic Forms of Parkinson’s Disease
Study Rationale: People with Parkinson’s disease (PD) experience different symptoms and disease course, even individuals with the same genetic form of PD. Because we do not yet understand the range of...
-
Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023SUPPLEMENT | Reducing Expression of the Gene for Alpha-synuclein in an Advanced Preclinical Model of Parkinson’s Disease
Study Rationale: Numerous genetic studies of families with parkinsonism and mutations in the alpha-synuclein gene suggest that an excess of alpha-synuclein leads to neurodegeneration and Parkinson’s...
-
Lysosomal Biomarkers Program, 2023Developing a Targeted Proteomic Test to Monitor Blood Samples for Lysosomal Signatures of Parkinson’s Disease
Study Rationale: Lysosomes are structures that help clear cells of molecular debris, and lysosomal dysfunction has been linked to neurodegeneration in Parkinson’s disease (PD). In this study, we will...
-
Lysosomal Biomarkers Program, 2023Measurement of Neuronal Extracellular Vesicles as a Blood-based Biomarker for Lysosomal Function
Study Rationale: Parkinson’s disease (PD) is associated with the aggregation of toxic proteins, a buildup due partly to the reduced ability of lysosomes to degrade these proteins. Improving lysosome...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.