The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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LRRK2 Target Engagement Ligand, 2011Development of LRRK2 Target Engagement Ligands
Objective/Rationale:
The overall objective of this project is to generate the data necessary to ultimately identify a small organic molecule capable of binding to a sub-domain of the LRRK2 protein... -
MJFF Research Grant, 2011Development of Functional Imaging for CB-1 and 5-HT1a in PD Participants with Dyskinesia
Objective/Rationale:
The goal of this proposal is to develop two imaging tests, [18F]MK-9470 and [18F]MPPF, to assess the function of two receptors (cannabinoid – CB-1 and serotonin receptor – 5-HT1a... -
MJFF Research Grant, 2011Evaluation of LRRK2-derived Bioportides as Functional Protein Modulators and Potential Therapeutics
Objective/Rationale:
The therapeutic actions of most existing drugs are the result of their binding to molecules known as proteins that are associated with certain cells of the human body. However... -
MJFF Research Grant, 2011Analysis of Adhesion and Chemotactic Factor Expression Possibly Involved in T Cell Brain Extravasation in Parkinson's Disease: A Human Postmortem Analysis
Objective/Rationale:
Brain infiltration of T cells has been identified in patients with Parkinson's disease and implicated in neurodegeneration in pre-clinical models. We hypothesize that peripheral T... -
MJFF Research Grant, 2011Assessing and Diagnosing Anxiety in Patients with Parkinson's Disease
Promising Outcomes of Original Grant:
A previous MJFF sponsored study showed that the available anxiety questionnaires are not suitable to assess anxiety in Parkinson’s disease (PD). The different... -
MJFF Research Grant, 2011Multimodal MRI Markers for Parkinson's Disease
Objective/Rationale:
A measurement tool which accurately reflects not only motor deficits but also a host of cognitive dysfunctions seen frequently in Parkinson’s disease (PD) would improve diagnosis...
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Our funding programs support basic, translational and clinical research from academia and industry.