The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Translational Pipeline Program, 2023Inhibiting Faulty DNA Repair as a Strategy for Preventing Neuronal Loss in Parkinson’s Disease
Study Rationale: Cells have mechanisms for repairing damaged DNA. Unfortunately, these repair mechanisms can themselves become inefficient and error-prone as we age — leading to the accumulation of...
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Biomarkers to Support Therapeutic Trials Program, 2023Using Neurophysiology as a Stratification Tool for Synucleinopathy
Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...
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Research Grant, 2022Extending Assessment of WATCH-PD Remote Digital Technology
Study Rationale: Digital tools can provide objective, sensitive, real-world measures of Parkinson’s disease (PD). Better measures could lead to more efficient, patient-centric and timely evaluation of...
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Translational Pipeline Program, 2022Investigating GPR55 as a Novel Neuroprotective Target in Preclinical Models of Parkinson’s Disease
Study Rationale: Cannabinoids — substances derived from the cannabis plant — have demonstrated neuroprotective properties useful for the treatment of neurodegenerative disorders. Although these...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Effects of Chemical Modifications on Aggregation of Alpha-synuclein
Study Rationale: Evidence suggests that alpha-synuclein causes the death of neurons in the brains of people with Parkinson’s disease (PD) by forming clusters (or ‘aggregates’) on the surface of...
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Expanding Biological Understanding of Parkinson's Disease, 2022Characterization of the Contributions of Alpha-synuclein and Tau Aggregation in a Preclinical Model of Parkinson’s Disease Progression
Study Rationale: Motor difficulties are not the only symptoms experienced by people with Parkinson’s disease (PD); up to 80% eventually develop dementia. This progression to dementia is associated...
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Our funding programs support basic, translational and clinical research from academia and industry.