The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2020Targeting of the Raphe-Cortical Pathway to Reduce Levodopa-Induced Psychosis
Study Rationale:
Parkinson’s disease is best known as a movement disorder, yet non-motor symptoms such as anxiety, depression and psychosis afflict over 50 percent of patients and severely impact... -
Research Grant, 2020More Than Pretty Pictures: Ion Imaging of Lipid Content and Flux Kinetics in Models of Parkinson’s Disease
Study Rationale:
Glycosphingolipids are natural cellular fats. They are components of cellular membranes that fulfill multiple functional roles, from cell structure and transport to signaling. The... -
Research Grant, 2020Identification of Therapeutic Circuits to Address Anxiety and Depression Symptoms in Parkinson’s Disease
Study Rationale: Parkinson’s disease patients often experience depression and anxiety. Addressing these non-motor symptoms has not been the focus of Parkinson’s disease research though psychiatric...
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Aligning Science Across Parkinson's, 2020Dissecting the Mechanisms Underlying Disease Progression
Study Rationale:
The progression of Parkinson’s disease is very variable, with some individuals having a rapid course and others having a longer and more benign course. We believe that by... -
Aligning Science Across Parkinson's, 2020Mapping the LRRK2 Signaling Pathway and Its Interplay with Other Parkinson’s Disease Components
Study Rationale:
Genetic mutations that lead to the activation of the enzyme LRRK2 are a major cause of inherited Parkinson's disease. We aim to combine the complementary expertise of our four... -
Aligning Science Across Parkinson's, 2020Role of PD-related Proteins as Drivers of Disease through Modulation of Innate and Adaptive Immunity
Study Rationale:
The hallmark motor impairments in Parkinson’s disease patients are due to the progressive loss of a special type of neuron in the brain using the chemical messenger dopamine. The...
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Our funding programs support basic, translational and clinical research from academia and industry.