The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers to Support Therapeutic Trials Program, 2022Identifying Biomarkers for a Mitochondrial Subtype of Parkinson’s Disease
Study Rationale: Increasing evidence suggests that the disorder we refer to as Parkinson’s disease (PD) might represent several diseases, each driven by different biological mechanisms. The...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2022Advancing Biological Understanding of PINK1 and Parkin Rodent Models of Parkinson’s Disease
Study Rationale: Although loss-of-function mutations in the PINK1 and Parkin genes are known to cause early onset Parkinson’s disease (PD), the cellular and molecular mechanisms remain uncertain. We...
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Translational Pipeline Program, 2022Prevention of Dementia in GBA-associated Parkinson’s Disease
Study Rationale: Whereas motor symptoms can be well controlled by dopamine-enhancing drugs and deep brain stimulation, dementia represents a key milestone in the course of Parkinson’s disease (PD)...
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Research Grant, 2022Establishing a Parkinson’s Disease Registry in West Virginia
Study Rationale: The state of West Virginia has one of the nation’s highest rates of Parkinson’s disease (PD), a condition for which the causes are not well understood and there is no cure. In April...
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Translational Pipeline Program, 2022Development of a Nurr1 Activator as a Novel Therapeutic for Parkinson’s Disease
Study Rationale: Nurr1 is a protein that works in the nucleus of dopamine-producing nerve cells in the brain to keep these cells functioning normally. Emerging evidence suggests that impaired function...
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Research Grant, 2022Longitudinal Endpoint Optimization to Provide an Assessment of Relevant Drugs in Parkinson’s Disease (LEOPARD-PD)
Study Rationale: The Parkinson’s Disease-Health Index (PD-HI) is a novel, disease specific patient-reported outcome (PRO) measure designed for use in clinical trials to track clinically meaningful...
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Our funding programs support basic, translational and clinical research from academia and industry.