The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2022Assessing the Effects of USP30 Inhibitors on the Removal of Damaged Mitochondria in Nerve Cells
Study Rationale: Mitochondrial dysfunction is extensively associated with genetic and sporadic forms of Parkinson’s disease (PD). Yet there are currently no clinical trials that specifically aim to...
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Research Grant, 2022Monitoring Prodromal and De Novo Parkinson’s Disease (PRONOVO) Using Multi-modal Imaging
Study Rationale: Individuals with Parkinson’s disease (PD) display variable impairment of the brain and peripheral nervous system, suggesting that PD includes a range of subtypes. Yet the underlying...
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Research Grant, 2022Using Integrated Biomarkers of Prodromal Parkinson’s Disease to Assess the Efficacy of Exercise Intervention in the Earliest Phase of Disease
Study Rationale: In individuals with Parkinson’s disease (PD), the pathological processes are already advanced by the time a clinical diagnosis is made. This delay contributes to the difficulty in...
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Research Grant, 2022LEARN-ATMP – Using the Patient Voice to Develop a Framework for Accessible ATMP Trials
Study Rationale: New therapies for Parkinson’s disease (PD) that involve the use of cells or genes — sometimes called advanced therapy medicinal products (ATMP) — are being developed and tested in...
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Accelerating the Translation of Parkinson's Disease Therapies, 2022Testing Small Molecules that Activate Removal of Cellular Debris for the Treatment of Parkinson’s Disease
Study Rationale:
People with Parkinson’s disease (PD) exhibit a diminished ability to remove cellular trash — including old and damaged molecules and organelles — from the brain. This impairment is... -
Research Grant, 2022Development of PET Tracer for Imaging SV2C in Parkinson's Disease
Study Rationale: Cells in the brain uses molecules such as dopamine, the neurotransmitter that is depleted in people with Parkinson’s disease (PD), to transmit signals from one to another. The...
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Our funding programs support basic, translational and clinical research from academia and industry.