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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2019
    Inhibition of LRRK2 Roc-COR GTPase

    Study Rationale:
    The LRRK2 protein is overactive in people with Parkinson’s and a mutation in the LRRK2 gene. Recent research shows LRRK2 may be overactive in a sporadic (cause unknown) Parkinson’s...

  • Therapeutic Pipeline Program, 2019
    Managing Levodopa-induced Dyskinesias by Targeting Dopamine D1 Receptor Signaling

    Study Rationale:
    Parkinson’s is a complex brain disease caused by the gradual loss of brain cells producing the neurotransmitter dopamine, which controls movement, emotion and affect. However...

  • Research Grant, 2019
    Tool to Identify Parkinson’s Disease Using Digital Facial Expression Biomarkers

    Study Rationale:
    Traditional Parkinson’s disease (PD) detection and monitoring systems lack objective biomarkers and are often reliant on late-stage symptoms. By contrast, a masked face is often seen...

  • Epidemiological Parkinson's Risk Modifiers, 2019
    Study in Finnish Population to Identify Therapies with Repurposing Potential for Parkinson’s Disease

    Study Rationale:
    Effective treatments for slowing the progression of Parkinson’s disease are urgently needed. Searching for possible treatments among drugs already used for other indications is a...

  • Epidemiological Parkinson's Risk Modifiers, 2019
    Study in Norwegian Population to Identify Therapies with Repurposing Potential for Parkinson’s Disease

    Study Rationale:
    There are not yet medicines that can prevent or slow Parkinson’s disease. Developing a new therapeutic can cost up to 2.6 billion dollars and takes many years of screening, chemistry...

  • Therapeutic Pipeline Program, 2019
    Biomaterial-enhanced Cellular Brain Repair for Parkinson's Disease

    Study Rationale:
    One promising approach for the treatment of Parkinson’s is to replace the cells that have died in the disease through transplantation of healthy cells into the brain. However, this...

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