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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fall 2020 RFA: Therapeutic Pipeline Program-Pre-Clinical, 2022
    Targeting Colony-stimulating Factor 1 Receptor (CSF1R) to Modify Disease Progression in Preclinical Experimental Models of Parkinson’s Disease

    Study Rationale: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by pronounced neuroimmune dysfunction. Although the disease is very common, no therapy is available...

  • Rapid Response Innovation Awards, 2014
    Reduced Habitual Intrusions: An Early Marker of Parkinson's Disease?

    Study Rationale:                   
    Parkinson's disease is characterized by the loss of a neurotransmitter called dopamine in a part of the brain called the basal ganglia. Parts of this region are...

  • PD Subtypes, 2007
    Prediction of Death, Dementia, Disability, Depression from the Time Course of UPDRS Motor Status

    Parkinson’s disease is progressive. Early on, its effects are relatively minor, affecting mainly movement and causing shaking of the limbs. Later on, serious events -- early death, dementia...

  • Prescott Family Initiative at the Arizona Parkinson's Diseas, 2009
    Arizona Parkinson's Disease Consortium: Predictors of Parkinson’s Disease and Parkinson’s Disease-Dementia

    Promising Outcomes of Original Grant: 
    The goals of the original grant were to expand the number of PD patients enrolled, incorporate new questionnaires for recording non-motor manifestations of PD...

  • Rapid Response Innovation Awards, 2014
    Mirtazapine as a Treatment for Pathological Gambling

    Objective/Rationale:             
    Pramipexole (Mirapex®) is a drug that is effective at alleviating movement deficits associated with Parkinson’s disease. However, pramipexole can induce compulsive...

  • Research Grant, 2022
    Expanding Genetic Analyses in Parkinson’s Disease

    Study Rationale: There is a critical need for greater understanding of the genetic component of Parkinson’s disease, both to predict and diagnose disease, but also to inform drug development efforts...

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