The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Non-pharmacological Interventions for Gait and Balance, 2019Optimizing Vibration Therapy to Improve Gait and Balance in Parkinson's Disease
Study Rationale:
Many people who have Parkinson's disease experience freezing of gait, which is an inability to walk despite intention to walk. Unfortunately, drugs rarely help with this problem... -
Non-pharmacological Interventions for Gait and Balance, 2019Project Holocue: Smart Wearable Assistive Cueing Device for Reducing Freezing of Gait
Study Rationale:
Cues, such as stripes on the ground, may help alleviate and sometimes even prevent freezing of gait in people with Parkinson's disease. However, different people prefer different... -
Non-pharmacological Interventions for Gait and Balance, 2019Vibrating Socks: A Novel Cueing Intervention to Reduce Freezing of Gait in Parkinson's Disease
Study Rationale:
Freezing of gait is a common and disabling symptom in Parkinson's disease. With freezing of gait, patients have the feeling that their feet are suddenly glued to the floor when they... -
Biomarkers of Protein Handling/Autophagy, Exosomes and Lipid, 2019Studying Blood Proteins to Improve Diagnosis and Tracking of Parkinson's Disease
Study Rationale:
Mutations (changes) in protein LRRK2 is the main genetic cause of Parkinson's disease (PD). In the past, we found that LRRK2 interacts with ribosomes, cellular protein factories. We... -
Alpha-synculein Biology and Therapies, 2018Ordering the Earliest Neuronal Response Events to Native Alpha-synuclein Exposure
Study Rationale:
The protein alpha-synuclein forms aggregates in the brains of people with Parkinson’s. Here, we will not look at the end stage of protein aggregation and cell death, which has been... -
Alpha-synculein Biology and Therapies, 2018Structure and Function of Alpha-synuclein at the Pre-synapse
Study Rationale:
Current therapeutic strategies against synucleinopathies aim to either stabilize a native form of alpha-synuclein or to reduce its levels in patients. However, the normal...
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Our funding programs support basic, translational and clinical research from academia and industry.