The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Identifying and Characterizing Genetic Causes of REM Sleep Behavior Disorder and Parkinson’s Disease
Study Rationale:
During the rapid eye movement (REM) phase of sleep, when we dream, our voluntary muscles are paralyzed so that we would not act out our dreams. In REM sleep behavior... -
Dyskinesia Challenge, 2014Gene-to-gene Interaction Analysis of Levodopa-induced Dyskinesia
Study Rationale:
Long-term treatment for Parkinson’s with levodopa can cause dyskinesia or involuntary movements. Other drugs like anti-dopaminergics can cause similar abnormal... -
Research Grant, 2014Neuromelanin in Circulating Phagocytes May Reveal Early Neurodegeneration in Parkinson's Disease Supplement
Promising Outcomes of Original Grant:
The pigment neuromelanin is specifically found in the nerves destroyed by Parkinson’s disease. We developed a way to measure neuromelanin and then looked for... -
Research Grant, 2014Phase IB Follow-up Study to Assess Boost Immunization with AFFITOPE® PD01A
Study Rationale:
PD01A is an alpha-synuclein-targeting vaccine. Accumulation and/or aggregation of alpha-synuclein is central to the pathogenesis of Parkinson’s disease, and its reduction is expected... -
Access to Data and Biospecimens, 2014Diurnal Fluctuations in Secreted Inflammatory Factors
Study Rationale/Hypothesis:
The goal of this study is to determine the extent to which inflammatory factors in biofluids (cerebrospinal fluid, plasma and serum) vary throughout the course of a given... -
Access to Data and Biospecimens, 201414-3-3 Phosphorylation as a Biomarker for Parkinson’s Disease
Study Rationale:
Disruption of 14-3-3 proteins is implicated in PD, and we have previously demonstrated that increasing 14-3-3 expression is protective in PD models. Recently, we...
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