The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2012VPS35 as a Novel Target for Parkinson's Disease
Objective/Rationale:
Mutations in the VPS35 gene were recently identified as a cause of autosomal dominant familial Parkinson's disease (PD). How mutations in VPS35 precipitate the demise of...
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Research Grant, 2015Development of a Radioligand for Imaging of Alpha-synuclein with Positron Emission Tomography
Study Rationale:
The visualization of alpha-synuclein deposition in the living human brain is of high need as a biomarker for Parkinson´s disease (PD). Positron emission tomography... -
Target Validation, 2015Synapsin III: A Novel Therapeutic Target for Parkinson’s Disease
Objective/Rationale:
In Parkinson’s disease (PD) accumulation of alpha-synuclein at striatal synapses, the neuronal sites of dopamine release, is believed to trigger cell degeneration. We have found... -
Research Grant, 2015Delivery of Cerebral Dopamine Neurotrophic Factor with Microbubbles and MRI-guided Focused Ultrasound (Supplement)
Promising Outcomes of Original Grant:
We achieved our key goal of non-invasive, targeted delivery of therapeutic doses of CDNF drug to the brain regions affected by Parkinson’s [striatum (ST) and... -
Research Grant, 2014Role of LRRK2 in Alpha-synuclein-induced Neurodegeneration: Supplement
Promising Outcomes of Original Grant:
We seek to develop a robust and standardized pre-clinical model relevant to late-onset Parkinson’s disease (PD) that will identify clinically viable LRRK2 kinase... -
LRRK2 Cohort Consortium Resource Request, 2013Peripheral Blood-based Transcript Biomarkers for Prediction of Parkinson Disease in LRRK2 Mutation Carriers
Objective/Rationale:
Currently, there is no known marker that can be found in the human blood that can help to predict Parkinson's disease (PD). There is also no marker that can help...
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Our funding programs support basic, translational and clinical research from academia and industry.