The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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LRRK2 LEAPS, 2014Link between LRRK2, Alpha-synuclein and Lysosomal Function
Study Rationale:
Our goal is to test whether Parkinson’s disease (PD) patients carrying a LRRK2 mutation have an abnormality in their lysosomes, a part of a cell that is necessary for degrading waste... -
Alpha-synuclein Pathology, 2014Contrasting Pathological Versus Normal Alpha-synuclein Assemblies
Study Rationale:
Parkinson’s disease (PD) is characterized by Lewy bodies composed of the protein alpha-synuclein in dopamine-producing nerve cells. The protein aggregates are also... -
Research Grant, 2015VPAC2 Agonists Neuroprotective and Anti-inflammatory Effects in Parkinson's Disease
Study Rationale:
The adaptive and innate immune responses play intricate roles in modulating neuroinflammation and may be harnessed for neuroprotection from Parkinson’s disease. We... -
Alpha-synuclein Pathology, 2014Characterization and Validation of Disease-specific Alpha-synuclein Species
Study Rationale
Alpha-synuclein aggregates called Lewy bodies are the hallmark of Parkinson’s disease (PD). Methods to measure alpha-synuclein in cerebrospinal fluid do exist today. However, these... -
Alpha-synuclein Pathology, 2014Characterization and Validation of Disease-specific Alpha-synuclein Species in Cerebrospinal Fluid
Study Rationale:
The protein alpha-synuclein plays a major role in Parkinson’s disease (PD). Quantification of alpha-synuclein in biological fluids (e.g., cerebrospinal fluid) could... -
Access to Data and Biospecimens, 2014Purine Biomarkers of LRRK2 PD
Objective/Rationale:
Oxidative damage to brain cells — akin to rust on car parts — can build up in Parkinson’s disease (PD) and leads to break down of brain functions. Urate is a natural...
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Our funding programs support basic, translational and clinical research from academia and industry.