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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2019
    Assessment and Monitoring of Neuromotor Function through Advanced Dynamic Pose Estimation

    Study Rationale:
    Parkinson’s disease (PD) begins well before movement symptoms appear, and many people have a long journey to diagnosis. No objective test for Parkinson’s exists. If we are able to...

  • Alpha-synculein Biology and Therapies, 2018
    Ordering the Earliest Neuronal Response Events to Native Alpha-synuclein Exposure

    Study Rationale:
    The protein alpha-synuclein forms aggregates in the brains of people with Parkinson’s. Here, we will not look at the end stage of protein aggregation and cell death, which has been...

  • Alpha-synculein Biology and Therapies, 2018
    Structure and Function of Alpha-synuclein at the Pre-synapse

    Study Rationale:
    Current therapeutic strategies against synucleinopathies aim to either stabilize a native form of alpha-synuclein or to reduce its levels in patients. However, the normal...

  • Research Grant, 2019
    Measurement of BMP and NAG Activity in CSF Samples

    Study Rationale:
    Mutations in the LRRK2 gene are a common cause of dominantly inherited Parkinson’s disease (PD). Previous studies showed that urine levels of a lipid [di-22:6-bis(monoacylglycerol...

  • Aligning Science Across Parkinson's, 2019
    Global Parkinson’s Genetics Program (GP2)
    GP2 Logo

    GP2 is a resource of the Aligning Science Across Parkinson's (ASAP) InitiativeIt is an ambitious five-year program to genotype >150,000 volunteers around the world to further understand the genetic...

  • Research Grant, 2019
    Developing New 18F-based Brain Tracers for Imaging Synapse in the Human Brain

    Study Rationale:
    A synapse is a structure that allow nerve cells (neurons) to communicate with one another or with target cells. In the brain, changes in synaptic density are associated with a variety...

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