The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Fall 2021 RFP: Expanding Biological Understanding of PD, 2021Characterizing the Impact of a Protective LRRK2 Variant on Biochemical and Cellular Function
Study Rationale: The LRRK2 gene is one of the most important genes involved in increasing the risk of Parkinson’s disease (PD). Changes in the gene, called mutations, can cause people to develop PD –...
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Research Grant, 2021Evaluation of Digital Mobility Data to Identify Individuals at Risk of Developing Parkinson’s Disease
Study Rationale: Gait disturbances play a major role in the motor manifestation of Parkinson’s disease (PD). Traditional clinical assessments aimed at measuring motor deficits do not sufficiently...
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Fall 2021 RFP: Outcome Measures, 2022Use of Integrated, Multi-omic Data Analysis for Screening and Treatment of Parkinson’s Disease
Study Rationale: Current diagnostic criteria and treatment options are designed for the “average” person with Parkinson’s disease (PD). This one-size-fits-all approach ignores the huge biological and...
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Summer 2021 RFP: Expanding Biological Understanding of PD, 2021Assessment of LRRK2 Activity and Neurodegeneration Markers in Postmortem Brain Samples of Idiopathic and LRRK2-associated Parkinson’s Disease
Study Rationale: Genetic variance at the LRRK2 gene locus is associated with risk of Parkinson’s disease (PD). Most evidence suggests that this variation increases the activity of the encoded LRRK2...
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Fall 2021 RFP: Expanding Biological Understanding of PD, 2022Evaluation of Gene Products that Counteract the Action of LRRK2
Study Rationale: Although most cases of Parkinson’s disease (PD) are of unknown origin, some forms can be inherited. Mutations that activate the enzyme LRRK2 are a major cause of inherited PD, and...
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Fall 2021 RFP: Outcome Measures, 2022Development of Standardized Measurements for Monitoring the Progression of Parkinson’s Disease via MRI
Study Rationale: One of the difficulties in research towards new treatments in Parkinson’s disease (PD) is the diversity of disease presentations and the lack of tools to measure the effect of a...
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Our funding programs support basic, translational and clinical research from academia and industry.