The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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The Role of Protein Degradation in Parkinson's Disease, 2002Characterization of Dopaminergic Neurons in a Proteasome-transgenic Pre-Clinical Model
Almost all cells in the human body are constantly degrading old, often damaged proteins, a process that prevents the formation of protein aggregates and is vital to keep the cell alive and functioning...
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The Role of Protein Degradation in Parkinson's Disease, 2002In vivo functional and molecular studies in a new model of Parkinson's disease generated usingviral vectors to deliver human alpha-synuclein
Parkinson's disease (PD) is a progressive neurological disorder characterized by degeneration of the dopaminergic neurons of the substantia nigra. Although the majority of the cases appear...
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Biomarkers, 2002Metabolomic Profiling to Develop Biomarkers for Parkinson's Disease
Metabolomics is the comprehensive study of the repertoire of small molecules present in cells and tissues. The identities, concentrations, and fluxes of these molecules are a final product of...
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Biomarkers, 2002Assessing the Role of a-Synuclein, a Biomarker for Parkinson's Disease
Alpha-synuclein was first implicated in familial Parkinson's disease but is also a major component of the Lewy body pathology, found in sporadic disease. Over-expression of the gene in fruit flies is...
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Biomarkers, 2002Ultra High Field MRS Assessment of MPTP, Rotenone, & BSO Effects in Rodents
Recent technical developments with magnetic resonance spectroscopy (MRS) have provided an extraordinary ability to non-invasively monitor brain function in humans. The neurochemical biopsy afforded...
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Biomarkers, 2002Non-Invasive Markers of Oxidatvie Stress in Human Brain
Many current theories on the development of Parkinson's disease include the notion that changes in the biochemistry of the brain usually precede any structural changes, which can be picked up by MRI...
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Our funding programs support basic, translational and clinical research from academia and industry.