The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2020Mapping the LRRK2 Signaling Pathway and Its Interplay with Other Parkinson’s Disease Components
Study Rationale:
Genetic mutations that lead to the activation of the enzyme LRRK2 are a major cause of inherited Parkinson's disease. We aim to combine the complementary expertise of our four... -
Aligning Science Across Parkinson's, 2020Role of PD-related Proteins as Drivers of Disease through Modulation of Innate and Adaptive Immunity
Study Rationale:
The hallmark motor impairments in Parkinson’s disease patients are due to the progressive loss of a special type of neuron in the brain using the chemical messenger dopamine. The... -
Aligning Science Across Parkinson's, 2020Tracing the Origin and Progression of Parkinson’s Disease through the Neuro-immune Interactome
Study Rationale:
While inflammation of the brain caused by immune cells has been implicated in Parkinson’s disease (PD), it is unknown whether these cells attacking the brain initiate the disease... -
Aligning Science Across Parkinson's, 2020Mechanisms Overwhelming Protein and Organelle Quality Control in Parkinson’s Disease
Study Rationale:
Abnormal protein aggregation and prion-like aggregate spreading are hallmarks of the degenerative cascades of sporadic and familial Parkinson’s disease (PD) and can damage cells... -
Aligning Science Across Parkinson's, 2020In Vivo Approach to Elucidate the Pathobiology of Parkinson’s-associated Genes Using Human Diseased Neurons
Study Rationale:
Several genes are known to be associated with Parkinson’s disease, although how they impact the disease process is not fully understood. Here we will use stem cells from patients in... -
Aligning Science Across Parkinson's, 2020Senescence in Parkinson’s Disease and Related Disorders
Study Rationale:
While aging is the greatest risk factor for development of Parkinson’s disease (PD), how aging promotes PD is not fully understood. Examining the role of cellular senescence...
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Our funding programs support basic, translational and clinical research from academia and industry.