The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Epidemiological Parkinson's Risk Modifiers, 2019Association of Dietary Patterns with Parkinson’s Symptoms and Pathology
Study Rationale:
Currently there is no preventive treatment for Parkinson’s disease. Our recent analyses has indicated that healthy dietary patterns such as the MIND (Mediterranean-DASH Intervention... -
Research Grant, 2019Assessment and Monitoring of Neuromotor Function through Advanced Dynamic Pose Estimation
Study Rationale:
Parkinson’s disease (PD) begins well before movement symptoms appear, and many people have a long journey to diagnosis. No objective test for Parkinson’s exists. If we are able to... -
Improved Biomarkers and Clinical Outcome Measures, 2019International Validation of Two Non-motor Symptom Scales in Parkinson’s Disease
Study Rationale:
Non-motor Parkinson’s symptoms can fluctuate with dopaminergic medication effectiveness. Anxiety, sadness, lack of energy and fatigue are common symptoms during the off-medication... -
Target Advancement Program, 2019Identifying Protein Sequence of Potential Drug Target Synuclein Nitrase
Study Rationale:
We have found that alpha-synuclein nitration and aggregation — which may play a role in Parkinson’s disease — is catalyzed by an enzyme that we have termed synuclein nitrase. In this... -
Target Advancement Program, 2019Chaperone-mediated Autophagy to Counteract Alpha-synuclein Pathology
Study Rationale:
A hallmark of Parkinson’s disease (PD) is aggregates of the protein alpha-synuclein. One of the main pathways to remove excess amounts of alpha-synuclein, which can be toxic for the... -
Research Grant, 2019Parkinson’s Digital Biomarker DREAM Challenges to Develop Measures of Symptoms and Severity
Study Rationale:
The use of wearable sensors to detect and measure Parkinson’s disease shows great promise. However how to convert the raw data to specific measures is poorly understood. We propose a...
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Our funding programs support basic, translational and clinical research from academia and industry.