To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
AAV Mouse SNCA 3xmiR/GFP Plasmid
DNA Plasmids
Viral transgene plasmid used in the AAV Mouse SNCA 3xmiR/GFP viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit groups only. RRID:Addgene_194248
AAV2/5 Empty Vector Control
DNA Plasmids
Viral transgene plasmid used in the AAV empty vector control viral vector for the AAV WT human alpha-synuclein viral vector, both available through Charles River Labs (see viral vector section). This plasmid is available to non-profit and for-profit groups. RRID:Addgene_194245
AAV2/5 CBh WT Alpha-Synuclein Plasmid
DNA Plasmids
Viral transgene plasmid used in the AAV2/5 WT alpha-synuclein viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit and for-profit groups. RRID:Addgene_194244
ATP13A2 Antibody
Antibody
Rabbit monoclonal antibody directed against mouse ATP13A2 for immunoblotting, immunostaining, and immunoprecipitation applications.
Estimated Availability: Early 2026
Floxed S69R Rab32 Mouse
Mouse Model
Mouse expressing the S69R point mutation in the mouse Rab32 gene (corresponds to the S71R mutation in human Rab32). LoxP sites flank the Rab32 gene to enable conditional Cre-mediated knockout.
Estimated Availability: Early 2026
iMCI-PARK Mouse*
Mouse Model
Inducible MCI-PARK (iMCI-PARK) mice, based on the ESR-NDUFS2 strain described by Fernández-Agüera, 2015, were generated by crossing mice carrying a floxed allele of mouse Ndufs2 with mice that broadly express tamoxifen-inducible cre recombinase (Tg(CAG-cre/Esr1*)5Amc that result in a conditional, body-wide knock-out of Ndufs2 following tamoxifen induction. Model was originally designed by deleting Ndufs2 only from dopaminergic neurons by D. James Surmeier at Northwestern University and made available through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:038571
LRRK2 KO Rat
Rat Model
CRISPR/Cas9 genome targeting strategy to knockout LRRK2 on a Sprague Dawley rat background.
Estimated Availability: Early 2026
Parkin KO x Polg Mutator Mouse*
Mouse Model
Parkin KO x Polg Mutator mice were generated by crossing PolgAD257A mutant mice, lacking mitochondria polymerase proofreading function, with Parkin KO mice. Model was designed by Kelly Stauch and Howard Fox at University of Nebraska Medical Center and made available through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:036670
PINK1 KO Rat
Rat Model
CRISPR/Cas9 genome targeting strategy to knockout PINK1 on a Sprague Dawley rat background.
Estimated Availability: Late 2025
Parkin KO Rat
Rat Model
CRISPR/Cas9 genome targeting strategy to knockout Parkin on a Sprague Dawley rat background.
Estimated Availability: Late 2025
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic