To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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TH-GFP Rat (non-X-linked)
Rat Model
Rats expressing green fluorescent protein (GFP) under the rat tyrosine hydroxylase (TH) promotor. This is a non-X-linked mutation.
Thy-1 Wild Type Human Alpha-Synuclein Mouse (Line 15)
Mouse Model
Transgenic mice expressing wild type human alpha-synuclein directed by the murine Thy-1 promoter. Two separate founder lines with different expression levels are available. RRID:IMSR_JAX:017682
Thy-1 Wild Type Human Alpha-Synuclein Mouse (Line 61)*
Mouse Model
Transgenic mice expressing wild type human alpha-synuclein cDNA driven by the mouse Thy1 promoter. Model was developed by Eliezer Masliah and deposited by Robert Rissman at University of California San Diego, and made available through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:038796
TMEM115 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse TMEM115 for immunoprecipitation of endogenous golgi.
Estimated Availability: Mid 2026
TMEM175 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse TMEM175 for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
TMEM175 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in TMEM175, including heterozygous and homozygous M393T mutations. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by Aligning Science Across Parkinson's (ASAP). *Heterozygous and homozygous Q65P mutations are currently in development. Estimated Availability: Q1 2026.
TMEM192 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse TMEM192 for immunoprecipitation of endogenous lysosomes.
Estimated Availability: Late 2025
TOMM20 Ubiquitinated at K56/61 Antibody
Antibody
Rabbit monoclonal antibody directed against the K56/61-ubiquitinated TOMM20.
Estimated Availability: Late 2025
Total DJ-1 Antibody
Antibody
Mouse monoclonal antibody directed against full length DJ-1. Ideal for use in immunoblotting or immunoassays.
Total Parkin Antibody
Antibody
Monoclonal mouse antibody directed against human Parkin. Suitable for immunoblot experiments.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic