To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
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AAV Human SNCA 3xmiR/GFP Plasmid
DNA Plasmids
Viral transgene plasmid used in the AAV Human SNCA 3xmiR/GFP viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit groups only. RRID:Addgene_194247
Progranulin Antibody
Antibody
Rabbit monoclonal antibody directed against human progranulin. Developed for use in immunoblotting, immunocytochemistry and immunoprecipitation applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative. Anticipated Availability: Q4 2027
EIF2AK1 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse EIF2AK1. Developed for use in immunoblotting and immunocytochemistry applications. Anticipated Availability: Q4 2027
Alpha-Synuclein O-GlcNAc T72 Antibody
Antibody
Rabbit monoclonal antibody specific to human and mouse alpha-synuclein when modified with O-GlcNAc at Threonine 72 (O-GlcNAc T72 aSyn). Developed for use in immunoblotting, immunofluorescence, and ELISA applications. This antibody development project is part of the MJFF Targets to Therapies (T2T) Initiative. Anticipated Availability: Q4 2027
AAK1 pS623 Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 623 of AAK1. This antibody failed validation and will not be made available.
ITPKB Antibody
Antibody
Rabbit monoclonal antibody directed against human ITPKB. Developed for use in immunoblotting, immunocytochemistry, and immunoprecipitation applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative. Anticipated Availability: Q4 2027
LRRK2 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse LRRK2. Developed for use in immunocytochemistry applications. Anticipated Availability: Q4 2027
CLN3 Antibody
Antibody
Rabbit monoclonal antibody directed against human CLN3. Developed for use in immunoblotting, immunocytochemistry, and immunoprecipitation applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative. Anticipated Availability: Q4 2027
TOMM20 Ubiquitinated at K56/61 Antibody
Antibody
Rabbit monoclonal antibody directed against the K56/61-ubiquitinated TOMM20. This antibody failed development as it lacked sensitivity to detect endogenous ubiquitinated TOMM20.
Ubiquitinated-K266 VDAC1 Antibody
Antibody
Monoclonal antibody directed against ubiquitinated-K266 VDAC1. This antibody failed development due to a lack of sensitivity.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic